Results 241 to 250 of about 1,386,772 (353)

SnapShot: Cancer Metabolism Pathways

Cell Metabolism, 2013
Jiangbin Ye, Craig B. Thompson, Patrick S. Ward, Lydia W.S. Finley, Ji Zhang   +4 more
openaire   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

CpG-oligodeoxynucleotides challenged macrophages ameliorate acetaminophen induced liver injury by activating TLR9/IRG1/itaconate metabolic pathway. [PDF]

Mol Med
Qu Y, Jiang Z, Chen Z, Luo S, Xie B, Wu X, Yuan G, Wu K, Chen L, Tian T, Li S, Luo H, Li Q, Yuan D, Zhang Y, Gao Y, Zhou J, Yan Z, Jiang Y.   +18 more
europepmc   +1 more source

Metabolism of chlorofluorocarbons and polybrominated compounds by Pseudomonas putida G786(pHG-2) via an engineered metabolic pathway

, 1994
Hor Gil Hur, Michael J. Sadowsky, Lawrence P. Wackett   +2 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Elucidating a novel metabolic pathway for enhanced antimicrobial glycolipid biosurfactant production in the yeast Meyerozyma guilliermondii. [PDF]

Sci Rep
Songdech P, Jayasekara LACB, Watchaputi K, Butkinaree C, Yingchutrakul Y, Soontorngun N.   +5 more
europepmc   +1 more source

Novel metabolic pathways of glutathione conjugates and their relation to toxicity.

, 1990
Hiroki Tomisawa, Mitsuru Tateishi
openalex   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Pharmacokinetic studies of mofezolac. III: Differences of metabolic pathways brought by animal differences.

, 1990
Hirotoshi MASUDA, Takashi Suzuki, Takashi Kawauchi, Takashi Shindo, Yasuro KAWAGUCHI   +4 more
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source