Results 91 to 100 of about 3,241,184 (308)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Active Learning for Basic Metabolic Pathways
Journal of Microbiology & Biology Education, 2014 Understanding the basic cellular function of metabolic pathways and how those pathways interact in cellular metabolism is a foundational concept in microbiology and general biology.
Sonja B. Yung, Todd P. Primm
doaj +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
The metabolic network profile based on the known metabolic pathways.
, 2016 The metabolic network profile based on the known metabolic pathways.
Pei Liu (93392) +8 more
core +1 more source
Stability of metabolic pathways with irreversible reactions [PDF]
, 2014 By making minimal assumptions on the kinetics of chemical reactions we study the stability of steady states in metabolic pathways in relation to the topology of the metabolic network.
van der Schaft, A.J.; id_orcid +2 more
core +4 more sources
Single-cell analysis of lung cancer metabolism and its clinical implications
Cancer Treatment and Research CommunicationsBackground: Lung cancer is a highly prevalent and invasive malignancy, characterized by profound metabolic reprogramming as one of its key features.
Xinglong Li +7 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Correlation between genera and metabolic secondary pathways.
, 2020 Correlation between genera and metabolic secondary pathways.
Haibo Chang (4691578) +8 more
core +1 more source
BMC Medical GenomicsBackground Osteogenesis imperfecta (OI) is a rare genetic bone disorder for which treatment options remain limited. Disease-specific induced pluripotent stem cells (iPSCs) offer a valuable model to investigate its underlying pathological mechanisms ...
Ruijun Guo +7 more
doaj +1 more source