Diverse mechanisms associated with cyhalofop-butyl resistance in Chinese sprangletop (Leptochloa chinensis (L.) Nees): Characterization of target-site mutations and metabolic resistance-related genes in two resistant populations [PDF]
Frontiers in Plant Science, 2022 Resistance of Chinese sprangletop (Leptochloa chinensis (L.) Nees) to the herbicide cyhalofop-butyl has recently become a severe problem in rice cultivation. However, the molecular mechanisms of target-site resistance (TSR) in cyhalofop-butyl-resistant L.
Yi Zhang +5 more
doaj +2 more sources
Cytochrome P450 and Glutathione S-Transferase Confer Metabolic Resistance to SYP-14288 and Multi-Drug Resistance in Rhizoctonia solani [PDF]
Frontiers in Microbiology, 2022 SYP-14288 is a fungicide as an uncoupler of oxidative phosphorylation, which is effective in controlling fungal pathogens like Rhizoctonia solani. To determine whether R.
Xingkai Cheng +9 more
doaj +2 more sources
Metabolic Resistance in Permethrin-Resistant Florida Aedes aegypti (Diptera: Culicidae) [PDF]
Insects, 2021 Aedes aegypti is the principal mosquito vector for many arthropod-borne viruses (arboviruses) including dengue, chikungunya, and Zika. In the United States, excessive permethrin use has led to a high frequency of resistance in mosquitoes.
Sierra M. Schluep, Eva A. Buckner
doaj +2 more sources
Metabolic Plasticity in Chemotherapy Resistance [PDF]
Frontiers in Oncology, 2020 Resistance of cancer cells to chemotherapy is the first cause of cancer-associated death. Thus, new strategies to deal with the evasion of drug response and to improve clinical outcomes are needed.
Maria Andrea Desbats +5 more
doaj +3 more sources
Metabolic checkpoint of ferroptosis resistance [PDF]
Molecular & Cellular Oncology, 2021 The metabolic checkpoint of ferroptosis remains obscure. We find that glucose favors system xc− inhibitor-induced ferroptosis by activating pyruvate oxidation, thereby promoting fatty acid synthesis and subsequent lipid peroxidation.
Jiao Liu, Rui Kang, Daolin Tang
doaj +3 more sources
Nutrient Scarcity in a New Defined Medium Reveals Metabolic Resistance to Antibiotics in the Fish Pathogen Piscirickettsia salmonis [PDF]
Frontiers in Microbiology, 2021 Extensive use of antibiotics has been the primary treatment for the Salmonid Rickettsial Septicemia, a salmonid disease caused by the bacterium Piscirickettsia salmonis. Occurrence of antibiotic resistance has been explored in various P.
Javiera Ortiz-Severín +14 more
doaj +2 more sources
Metabolic Resistance in Bed Bugs [PDF]
Insects, 2011 Blood-feeding insects have evolved resistance to various insecticides (organochlorines, pyrethroids, carbamates, etc.) through gene mutations and increased metabolism. Bed bugs (Cimex lectularius) are hematophagous ectoparasites that are poised to become
Omprakash Mittapalli +2 more
doaj +3 more sources
Metabolic mechanisms of immunotherapy resistance [PDF]
Exploration of Targeted Anti-tumor TherapyImmunotherapy has revolutionized cancer treatment, yet its efficacy is frequently compromised by metabolic mechanisms that drive resistance. Understanding how tumor metabolism shapes the immune microenvironment is essential for developing effective ...
Luis Cabezón-Gutiérrez +4 more
doaj +3 more sources
Monitoring Insecticide Susceptibility in Aedes Aegypti Populations from the Two Biggest Cities, Ouagadougou and Bobo-Dioulasso, in Burkina Faso: Implication of Metabolic Resistance [PDF]
Tropical Medicine and Infectious Disease, 2020 In West Africa, Aedes aegypti remains the major vector of dengue virus. Since 2013, dengue fever has been reemerging in Burkina Faso with annual outbreaks, thus becoming a major public health problem.
Moussa Namountougou +16 more
doaj +2 more sources
Pathogens, 2022 Malaria remains a major public health concern in Africa. Metabolic resistance in major malaria vectors such as An. funestus is jeopardizing the effectiveness of long-lasting insecticidal nets (LLINs) to control malaria.
Benjamin D. Menze +5 more
doaj +1 more source