Results 31 to 40 of about 1,437,206 (304)

Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism. [PDF]

open access: yes, 2017
Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of ...
Bordbar, Aarash   +5 more
core   +1 more source

Pro-197-Ser Mutation and Cytochrome P450-Mediated Metabolism Conferring Resistance to Flucarbazone-Sodium in Bromus japonicus

open access: yesPlants, 2022
In crop fields, resistance to acetolactate synthase (ALS)-inhibiting herbicides found in many troublesome weed species, including Bromus japonicus Thunb, is a worldwide problem. In particular, the development of herbicide resistance in B.
Yuning Lan   +7 more
doaj   +1 more source

Natriuretic peptides and cardiovascular damage in the metabolic syndrome. Molecular mechanisms and clinical implications [PDF]

open access: yes, 2010
Natriuretic peptides are endogenous antagonists of vasoconstrictor and salt- and water-retaining systems in the body's defence against blood pressure elevation and plasma volume expansion, through direct vasodilator, diuretic and natriuretic properties ...
ALONZO, ALESSANDRO   +4 more
core   +1 more source

From Global to Local—New Insights into Features of Pyrethroid Detoxification in Vector Mosquitoes

open access: yesInsects, 2021
The threat of mosquito-borne diseases continues to be a problem for public health in subtropical and tropical regions of the world; in response, there has been increased use of adulticidal insecticides, such as pyrethroids, in human habitation areas over
William C. Black   +4 more
doaj   +1 more source

Is acetylation a metabolic rheostat that regulates skeletal muscle insulin action? [PDF]

open access: yes, 2015
Skeletal muscle insulin resistance, which increases the risk for developing various metabolic diseases, including type 2 diabetes, is a common metabolic disorder in obesity and aging.
LaBarge, Samuel   +2 more
core   +2 more sources

Investigation of glutathione transferases at the gene regulation level in flufenacet resistant black-grass populations (Alopecurus myosuroides Huds.)

open access: yesJulius-Kühn-Archiv, 2022
The herbicide flufenacet, applied in pre-emergence, acts as an inhibitor of the synthesis of very long-chain fatty acids (HRAC group 15) and is an important component in the control of grasses in winter cereals, especially when resistance to other ...
Parcharidou. Evlampia   +2 more
doaj   +1 more source

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

open access: yes, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A   +2 more
core   +2 more sources

Role of a Critical Visceral Adipose Tissue Threshold (CVATT) in Metabolic Syndrome: Implications for Controlling Dietary Carbohydrates: A Review [PDF]

open access: yes, 2004
There are likely many scenarios and pathways that can lead to metabolic syndrome. This paper reviews mechanisms by which the accumulation of visceral adipose tissue (VAT) may contribute to the metabolic syndrome, and explores the paradigm of a critical ...
Freedland, Eric S.
core   +5 more sources

Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models. [PDF]

open access: yes, 2016
Metabolic syndrome (MetS), characterized as obesity, insulin resistance, and non-alcoholic fatty liver diseases (NAFLD), is associated with vitamin D insufficiency/deficiency in epidemiological studies, while the underlying mechanism is poorly addressed.
Cai, Linbi   +19 more
core   +2 more sources

Candidate Genes Involved in Tolerance to Fenoxaprop-P-Ethyl in Rice Induced by Isoxadifen-Ethyl Hydrolysate

open access: yesAgronomy, 2023
The metabolic resistance of plants to herbicides is similar to the herbicide metabolism process accelerated by safeners. The tolerance to fenoxaprop-P-ethyl (FE) is distinct among different varieties of rice in which phytotoxicity forms easily, resulting
Yaning Zhao   +6 more
doaj   +1 more source

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