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Essays in Biochemistry, 2020 Abstract Metabolism consists of a series of reactions that occur within cells of living organisms to sustain life. The process of metabolism involves many interconnected cellular pathways to ultimately provide cells with the energy required to carry out their function.
Ayesha Judge, Michael S. Dodd
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NAD+ Metabolism, Metabolic Stress, and Infection [PDF]
Frontiers in Molecular Biosciences, 2021 Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite with wide-ranging and significant roles in the cell. Defects in NAD+ metabolism have been associated with many human disorders; it is therefore an emerging therapeutic target. Moreover, NAD+ metabolism is perturbed during colonization by a variety of pathogens, either due to the ...
Groth, Benjamin +2 more
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Fructose Metabolism and Cardiac Metabolic Stress [PDF]
Frontiers in Pharmacology, 2021 Cardiovascular disease is one of the leading causes of mortality in diabetes. High fructose consumption has been linked with the development of diabetes and cardiovascular disease. Serum and cardiac tissue fructose levels are elevated in diabetic patients, and cardiac production of fructose via the intracellular polyol pathway is upregulated.
M. Annandale +11 more
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Glucocorticoids, metabolism and metabolic diseases [PDF]
Molecular and Cellular Endocrinology, 2007 Since the discovery of the beneficial effects of adrenocortical extracts for treating adrenal insufficiency more than 80 years ago, glucocorticoids (GC) and their cognate, intracellular receptor, the glucocorticoid receptor (GR) have been characterized as critical components of the delicate hormonal control system that determines energy homeostasis in ...
Vegiopoulos, Alexandros, Herzig, Stephan
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Position Statement on COVID-19 Infection and Diabetes
Journal of the ASEAN Federation of Endocrine Societies, 2020 Coronavirus disease 2019 (COVID-19) has affected millions of lives worldwide, posing unprecedented challenges to global public health. It has infected people of different backgrounds, and from all industries, including healthcare workers.
The Philippine Society of Endocrinology, Diabetes and Metabolism (PSEDM)
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Journal of Immunology Research, 2022 Circulating CD25hi B cells, a subset of regulatory B cells in humans, are closely related to inflammation and autoimmune diseases. This study is aimed at investigating the alternation of CD25hi Bregs and their correlation with CD4 effector and regulatory
Jie Zhang +9 more
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International Journal of Endocrinology, 2022 Background. X-linked adrenoleukodystrophy (ALD) is an inherited peroxisomal metabolism disorder, resulting from the loss-of-function mutation of ATP-binding cassette protein subfamily D1 (ABCD1) gene.
Bingzi Dong +8 more
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International Journal of Endocrinology, 2022 Aims/Introduction. Sex steroid hormones play a significant role in the progression of cardiovascular and metabolic diseases, including non-alcoholic fatty liver disease (NAFLD).
Xinxin Zhang +8 more
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Journal of Diabetes Research, 2021 Insulin treatment was confirmed to reduce insulin resistance, but the underlying mechanism remains unknown. Caveolin-1 (Cav-1) is a functional protein of the membrane lipid rafts, known as caveolae, and is widely expressed in mammalian adipose tissue ...
Hangya Peng +8 more
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International Journal of Endocrinology, 2023 Antiphospholipid syndrome (APS) is an autoimmune disorder while adrenal hemorrhage could be its rare complication. Herein, we report the case of a 32-year-old unmarried woman with a history of systemic lupus erythematosus (SLE) who was hospitalized after
Weiwei Jiang +5 more
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