Results 81 to 90 of about 140,358 (326)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Metabolizable energy and digestible amino acids of full-fat soybean without or with protease supplementation in diets for broilers

Ciência e Agrotecnologia
Two experiments were carried out to determine the energy values and the true ileal digestibility of amino acids of nine toasted full-fat soybeans (FFSB), without or with the addition of monocomponent protease.
Felipe Santos Dalólio, Luiz Fernando Teixeira Albino, Horácio Santiago Rostagno, Diego Ladeira da Silva, Maurílio de Lucas Xavier Júnior, Vinícius Duarte de Oliveira   +5 more
doaj   +1 more source

Partioning of dietary energy of chickens fed maize or wheat-based diets with and without a commercial blend of phytogenic feed additives [PDF]

, 2015
The aim of the study was to investigate the effects of a standardized mixture of a commercial blend of phytogenic feed additives containing 5% carvacrol, 3% cinnamaldehyde, and 2% capsicum on utilization of dietary energy and performance in broiler ...
Bravo, D., Fernándes Beccaccia, Amanda, Pirgozliev, V., Rose, S. P.   +3 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Effect of qualitative feed restriction on energy metabolism and nitrogen retention in sheep [PDF]

, 2009
Periodic restrictions in feed quality and quantity is an important phenomenon in regions where animal production should bridge the gap between periods of forage production separated by a dry season.
Kamalzadeh, A, Kiasat, A, Koops, WJ
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Effects of Nutritional Levels on Performance, Carcass Characteristics and Nutrient Digestibility of Sexed Broilers

Brazilian Journal of Poultry Science
The objective of this study was to evaluate the effects of dietary nutrient levels on performance, carcass yield, commercial cuts, digestibility and economical viability of broilers from 1 to 42 days of age.
JA Muñoz, D Suckeveris, LF Demuner, APO Saccomani, AL Silva, RT Silva, DE Faria Filho, DE Faria   +7 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Energy dynamics of broiler in thermoneutral or heat stress environments with different levels of metabolizable energy [PDF]

Ciência Rural
: Two experiments evaluated the effect of different levels of metabolizable energy (ME) on nutrient metabolizability, energy balance, and broiler performance under thermoneutral and cyclic heat stress conditions.
Maurício de Paula Ferreira Teixeira, Kamilla Ribas Soares, Ricardo Reis e Silva, Luiz Felipe Pinho Pereira, Cristiano Werneck Rocha Gondim, Mariana André Pompeu, Thiago Pajeú Nascimento, Nelson Carneiro Baião, Leonardo José Camargos Lara   +8 more
doaj   +1 more source

Density-dependent switches in diet:a likely mechanism for negative feedbacks on goose population increase? [PDF]

, 2009
Goose grazing on arctic tundra vegetation has shown both positive and negative effects on subsequent foraging conditions. To understand the potential of a density-dependent feedback on herbivore population size, the relation between grazing pressure and ...
Kuijper, Dries Pieter Jan, Loonen, M. J. J. E., Ubels, R.   +2 more
core   +1 more source