Results 191 to 200 of about 98,733 (348)

Positron Emission Tomography Imaging in Clinical Trials for Parkinson's Disease: Applications of Metabolic Brain Network Approach

Movement Disorders, EarlyView.
ABSTRACT Neuroimaging with positron emission tomography (PET) has been instrumental in elucidating neurobiological mechanisms behind therapeutical trials in Parkinson's disease (PD). A variety of medical and neurosurgical interventions have been evaluated using many radioligands that reveal molecular basis for target engagement and brain responses in ...
Vijay Dhawan, Shichun Peng, Phoebe G. Spetsieris, David Eidelberg, Yilong Ma   +4 more
wiley   +1 more source

Sexually dimorphic impact of prenatal hyperandrogenism on offspring growth trajectory in sheep. [PDF]

Sci Rep
Topaktas E, Ciarelli J, Domke S, Pallas B, Ghnenis A, Agarwal M, Goss C, Cho K, Shriver LP, Patti GJ, Padmanabhan V, Vyas AK.   +11 more
europepmc   +1 more source

THE CARDIAC PURINE METABOLOME DURING SEPSIS

, 2006
Wilbert Law, J. Ross, Beth A. Conlon
openalex   +1 more source

Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry [PDF]

, 2009
Akiyoshi Hirayama, Kenjiro Kami, Masahiro Sugimoto, Maki Sugawara, Naoko Toki, Hiroko Onozuka, Taira Kinoshitá, Norio Saito, Atsushi Ochiai, Masaru Tomita, Hiroyasu Esumi, Tomoyoshi Soga   +11 more
openalex   +1 more source

High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome

Gut, 2015
F. De Filippis, N. Pellegrini, L. Vannini, I. Jeffery, A. La Storia, L. Laghi, D. Serrazanetti, R. Di Cagno, I. Ferrocino, C. Lazzi, S. Turroni, L. Cocolin, P. Brigidi, E. Neviani, M. Gobbetti, P. O’Toole, D. Ercolini   +16 more
semanticscholar   +1 more source

Changes in Liver Metabolome Induced by Pterostilbene and Resveratrol in a Rat Model of Liver Steatosis

Molecular Nutrition &Food Research, EarlyView.
Resveratrol and pterostilbene reduced the steatotic status of animals fed a high‐fat, high‐sucrose diet, involving differential and specific mechanisms of action for each stilbene. Thus, changes in riboflavin metabolism, nicotinamide mononucleotide metabolism, or in the LysoPC(18:1)‐mediated effects contribute to the specific actions of pterostilbene ...
Alfredo Fernández‐Quintela, Emily P. Laveriano‐Santos, Tania Portolés, Andreu Gual‐Grau, Juan Vicente Sancho, Maria P. Portillo   +5 more
wiley   +1 more source

Inferred bi-directional interactions between vaginal microbiota, metabolome and persistent HPV infection accompanied by high-grade cervical intraepithelial neoplasia. [PDF]

BMC Microbiol
Yang Q, Dai W, Wu D, Xu R, Li C, Wu R, Du H.   +6 more
europepmc   +1 more source

Analytical Approaches toward Successful Human Cell Metabolome Studies by NMR Spectroscopy [PDF]

, 2009
Iola F. Duarte, Joana Marques, Ana Ladeirinha, Cláudia Rocha, Inês Lamego, Rita Calheiros, Tania Silva, M. Paula M. Marques, Joana Barbosa Melo, Isabel M. Carreira, Ana M. Gil   +10 more
openalex   +1 more source

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

Molecular Nutrition &Food Research, EarlyView.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang, Michelle Lee, Erika de Jesus, Katherine Weh, Connor Howard, Henriette Remmer, Amy B. Howell, Laura A. Kresty   +7 more
wiley   +1 more source

Disruption of gut microbiome and metabolome in treatment-naïve children with attention deficit hyperactivity disorder. [PDF]

BMC Microbiol
Han D, Zhang Y, Liu W, Wan R, Hu J, Pan F, Pan X, Weng W, Wang Y, Ma Z, Zhang H, Chen J.   +11 more
europepmc   +1 more source