Results 51 to 60 of about 161,779 (333)

Integrated analysis of the oral and intestinal microbiome and metabolome of elderly people with more than 26 original teeth: a pilot study

Frontiers in Microbiology, 2023
Elderly subjects with more than 20 natural teeth have a higher healthy life expectancy than those with few or no teeth. The oral microbiome and its metabolome are associated with oral health, and they are also associated with systemic health via the oral-
Yuichiro Nishimoto, Felix Salim, Felix Salim, Kazuma Yama, Kota Kumagai, Ryutaro Jo, Minori Harada, Yuki Maruyama, Yuto Aita, Narumi Fujii, Takuya Inokuchi, Ryosuke Kawamata, Misato Sako, Yuko Ichiba, Kota Tsutsumi, Mitsuo Kimura, Yuka Mori, Shinnosuke Murakami, Shinnosuke Murakami, Yasushi Kakizawa, Takashi Kumagai, Shinji Fukuda, Shinji Fukuda, Shinji Fukuda, Shinji Fukuda, Shinji Fukuda   +25 more
doaj   +1 more source

Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease

Nature Communications, 2020
Chronic obstructive pulmonary disease (COPD) is the third commonest cause of death globally, and manifests as a progressive inflammatory lung disease with no curative treatment. The lung microbiome contributes to COPD progression, but the function of the
K. Bowerman, S. F. Rehman, Annalicia Vaughan, Nancy Lachner, K. Budden, R. Kim, David L A Wood, S. Gellatly, S. Shukla, L. Wood, I. Yang, P. Wark, P. Hugenholtz, P. Hansbro   +13 more
semanticscholar   +1 more source

Preterm gut microbiota and metabolome following discharge from intensive care [PDF]

, 2015
The development of the preterm gut microbiome is important for immediate and longer-term health following birth. We aimed to determine if modifications to the preterm gut on the neonatal intensive care unit (NICU) impacted the gut microbiota and ...
Berrington, Janet, Cummings, Stephen, Embleton, Nicholas, Fernstad, Sara Johansson, Marrs, Emma, Nelson, Andrew, Perry, John, Skeath, Tom, Stewart, Christopher   +8 more
core   +1 more source

Metabolome-Defined Obesity and the Risk of Future Type 2 Diabetes and Mortality.

Diabetes Care, 2022
OBJECTIVE Obesity is a key risk factor for type 2 diabetes; however, up to 20% of patients are normal weight. Our aim was to identify metabolite patterns reproducibly predictive of BMI and subsequently to test whether lean individuals who carry an obese ...
F. Ottosson, E. Smith, U. Ericson, L. Brunkwall, M. Orho-Melander, S. Di Somma, Paola Antonini, P. Nilsson, C. Fernandez, O. Melander   +9 more
semanticscholar   +1 more source

Integrated fecal microbiome–metabolome signatures reflect stress and serotonin metabolism in irritable bowel syndrome

Gut microbes, 2022
To gain insight into the complex microbiome-gut-brain axis in irritable bowel syndrome (IBS), several modalities of biological and clinical data must be combined.
Z. Mujagic, M. Kasapi, D. Jonkers, I. García-Pérez, L. Vork, Z. Z. Weerts, J. Serrano-Contreras, A. Zhernakova, A. Kurilshikov, Jamie Scotcher, E. Holmes, C. Wijmenga, D. Keszthelyi, J. Nicholson, J. Posma, A. Masclee   +15 more
semanticscholar   +1 more source

Impact of phenylpropanoid compounds on heat stress tolerance in carrot cell cultures [PDF]

, 2016
The phenylpropanoid and flavonoid families include thousands of specialized metabolites that influence a wide range of processes in plants, including seed dispersal, auxin transport, photoprotection, mechanical support and protection against insect ...
Baldan, Barbara, Ceoldo, S, Commisso, M, Guzzo, F., Levi, M, Stocchero, M, Strazzer, P, Toffali, K   +7 more
core   +3 more sources

Metabolomic Profiling of Red Blood Cells to Identify Molecular Markers of Methotrexate Response in the Collagen Induced Arthritis Mouse Model

Future Pharmacology, 2022
Although methotrexate (MTX) is the first line disease-modifying therapy used in the treatment of autoimmune arthritis, it is limited by its unpredictable and variable response profile and lack of therapeutic biomarkers to predict or monitor therapeutic ...
Yezan M. Salamoun, Kishore Polireddy, Yu Kyoung Cho, Ryan Sol Funk   +3 more
doaj   +1 more source

Gut microbiome-metabolome interactions predict host condition

Microbiome
Background The effect of microbes on their human host is often mediated through changes in metabolite concentrations. As such, multiple tools have been proposed to predict metabolite concentrations from microbial taxa frequencies.
O. Shtossel, Omry Koren, I. Shai, E. Rinott, Y. Louzoun   +4 more
semanticscholar   +1 more source

Screening and optimization of indole-3-acetic acid production and phosphate solubilization by rhizobacterial strains isolated from Acacia cyanophylla root nodules and their effects on its plant growth

Journal of Genetic Engineering and Biotechnology, 2020
Background Plant growth-promoting rhizobacteria (PGPR) are known to improve plant growth and are used as biofertilizers, thanks to their numerous benefits to agriculture such as phosphorus solubilization and phytohormone production.
Sara Lebrazi, Karsten Niehaus, Hanna Bednarz, Mouhcine Fadil, Marwa Chraibi, Kawtar Fikri-Benbrahim   +5 more
doaj   +1 more source

Blood-brain barrier disruption defines the extracellular metabolome of live human high-grade gliomas

Communications Biology, 2023
The extracellular microenvironment modulates glioma behaviour. It remains unknown if blood-brain barrier disruption merely reflects or functionally supports glioma aggressiveness.
Cecile Riviere-Cazaux, Lucas P. Carlstrom, Karishma Rajani, Amanda Munoz-Casabella, Masum Rahman, Ali Gharibi-Loron, Desmond A. Brown, Kai J. Miller, Jaclyn J. White, Benjamin T. Himes, Ignacio Jusue-Torres, Samar Ikram, Seth C. Ransom, Renee Hirte, Ju-Hee Oh, William F. Elmquist, Jann N. Sarkaria, Rachael A. Vaubel, Moses Rodriguez, Arthur E. Warrington, Sani H. Kizilbash, Terry C. Burns   +21 more
doaj   +1 more source