Changes in thyroid hormone (TH) levels in rat brain at early developmental stages are correlated with adverse effects on offspring development. To characterize the ability of substances to interfere with the TH concentrations in, e.g., rat brain, it is ...
Christiane Hindrichs +6 more
doaj +1 more source
Metabolomics for Biomarker Discovery in Gastroenterological Cancer
The study of the omics cascade, which involves comprehensive investigations based on genomics, transcriptomics, proteomics, metabolomics, etc., has developed rapidly and now plays an important role in life science research.
Shin Nishiumi +5 more
doaj +1 more source
Time resolved cell painting enables rapid assessment of cell phenotypes
Cell Painting is an advanced imaging technique for drug discovery used to study cellular phenotypes by simultaneously labeling various organelles/structures and analyzing the resulting multidimensional phenotypic features through a sophisticated data ...
Franziska A. Hecker +4 more
doaj +1 more source
Metabolomic analysis by UAE-GC MS and antioxidant activity of Salvia hispanica (L.) seeds grown under different irrigation regimes [PDF]
Chia (Salvia hispanica L.) is an emerging crop with a high content of α-linolenic acid and metabolites of industrial and pharmaceutical interest but information on metabolome variations in response to agricultural management is scarce.
Amato, Mariana +4 more
core +2 more sources
MetaboTools: A comprehensive toolbox for analysis of genome-scale metabolic models [PDF]
Metabolomic data sets provide a direct read-out of cellular phenotypes and are increasingly generated to study biological questions. Our previous work revealed the potential of analyzing extracellular metabolomic data in the context of the metabolic ...
Aurich, Maike K. +2 more
core +3 more sources
Temporal effects of three-dimensional clinostat treatment on bone and serum metabolome in C57BL/J mice: a new method of simulating microgravity effect [PDF]
Chenchen Song +5 more
openalex +1 more source
From Single Constituents to Metabolomics in Food Quality Analysis [PDF]
Until now, a wide range of laboratory approaches has been employed for control of organic food quality and authenticity. In addition to widely used light isotope measurement based methods, various spectroscopic and/or chromatographic have been ...
Hajslova, Jana, Schulzova, Vera
core
Metabolomics-based biomarker discovery for bee health monitoring : a proof of concept study concerning nutritional stress in Bombus terrestris [PDF]
Bee pollinators are exposed to multiple natural and anthropogenic stressors. Understanding the effects of a single stressor in the complex environmental context of antagonistic/synergistic interactions is critical to pollinator monitoring and may serve ...
Meeus, Ivan +5 more
core +2 more sources
Environmental soil samples enriched with xanthan gum led to the discovery and isolation of a novel strain of motile Paenarthrobacter ilicis in Bielefeld, Germany, which possesses a previously uncharacterized xanthan utilization gene region on its sole ...
Michael Thomas +5 more
doaj +1 more source
Metabolome and transcriptome profiling provide insights into green apple peel reveals light- and UV-B-responsive pathway in anthocyanins accumulation [PDF]
Ruirui Ding +3 more
openalex +1 more source

