Results 71 to 80 of about 98,733 (348)
Cerebral low-molecular metabolites influenced by intestinal microbiota: a pilot study
Frontiers in Systems Neuroscience, 2013 Recent studies suggest that intestinal microbiota influences gut-brain communication. In this study, we aimed to clarify the influence of intestinal microbiota on cerebral metabolism. We analyzed the cerebral metabolome of germ-free (GF) mice and ex-germ-
Mitsuharu eMatsumoto +6 more
doaj +1 more source
mSphere, 2020 The contribution of human gastrointestinal (GI) microbiota and metabolites to host health has recently become much clearer. However, many confounding factors can influence the accuracy of gut microbiome and metabolome studies, resulting in ...
Yali Liang +10 more
doaj +1 more source
Metabolites, 2022 Prenatal exposure to phthalates, a family of endocrine-disrupting plasticizers, is associated with disruption of maternal metabolism and impaired neurodevelopment.
Mariana Parenti +8 more
doaj +1 more source
Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset
Science Translational Medicine, 2021 Peripheral blood dynamics in the 100 days before delivery reveal a transition from pregnancy maintenance to prelabor biology. Toward better prediction of labor Current methods to predict spontaneous labor are fairly inaccurate.
I. Stelzer +37 more
semanticscholar +1 more source
Advanced Science, EarlyView.In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu +10 more
wiley +1 more source
PlantsCinnamomum osmophloeum Kanehira (CO) is an endemic species of Taiwan. This study elucidated the composition of CO hydrosol, revealing trans-cinnamaldehyde (65.03%), trans-cinnamyl acetate (7.57%), and coumarin (4.31%) as the main volatile compounds ...
Chung-Hsuan Wang +4 more
doaj +1 more source
Metabolomics for the masses: The future of metabolomics in a personalized world [PDF]
European Journal of Molecular & Clinical Medicine, 2017 Current clinical practices focus on a small number of biochemical directly related to the pathophysiology with patients and thus only describe a very limited metabolome of a patient and fail to consider the interations of these small molecules.
Trivedi, Drupad +2 more
openaire +3 more sources
Advanced Science, EarlyView.The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou +11 more
wiley +1 more source
Accelerometer-Based Sedentary Time, Physical Activity, and Serum Metabolome in Young Men
Metabolites, 2022 Physical activity (PA) has been shown to associate with many health benefits but studies with metabolome-wide associations with PA are still lacking. Metabolome studies may deepen the mechanistic understanding of PA on the metabolic pathways related to ...
Jani P. Vaara +5 more
doaj +1 more source
Forage Crop Research in the Modern Age
Advanced Science, EarlyView.Forage crops are increasingly vital to sustainable agriculture, yet urgent demands for transformative innovations create unprecedented opportunities and challenges. This review synthesizes the latest advances in forage research, spotlighting cutting‐edge breeding technologies and their transformative potential.
Qikun Liu +11 more
wiley +1 more source