Results 1 to 10 of about 271,198 (347)
The metabolic consequences of HIV/TB co-infection
Background The synergy between the human immunodeficiency virus (HIV) and Mycobacterium tuberculosis during co-infection of a host is well known. While this synergy is known to be driven by immunological deterioration, the metabolic mechanisms that ...
Chandré Herbert+3 more
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Optimising a urinary extraction method for non-targeted GC–MS metabolomics
Urine is ideal for non-targeted metabolomics, providing valuable insights into normal and pathological cellular processes. Optimal extraction is critical since non-targeted metabolomics aims to analyse various compound classes.
Cara Olivier, Bianca Allen, Laneke Luies
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HIV-1 Tat amino acid residues that influence Tat-TAR binding affinity: a scoping review
HIV-1 remains a global health concern and to date, nearly 38 million people are living with HIV. The complexity of HIV-1 pathogenesis and its subsequent prevalence is influenced by several factors including the HIV-1 subtype.
Piwai Terry Gotora+2 more
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Transcriptionally imprinted glycomic signatures of acute myeloid leukemia
Background Acute myeloid leukemia (AML) is a genetically and phenotypically heterogeneous disease that has been suffering from stagnant survival curves for decades.
Constantin Blöchl+4 more
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The highly adaptive cellular response of Mycobacterium tuberculosis to various antibiotics and the high costs for clinical trials, hampers the development of novel antimicrobial agents with improved efficacy and safety.
Kirsten E. Knoll+2 more
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The AbsoluteIDQ p400 HR kit is a commercial product for targeted metabolomics. While the kit has been validated for human plasma and serum, adherent cell lysates have not yet been evaluated.
Raphaela Fritsche-Guenther+3 more
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Background Puccinia striiformis f. sp. tritici (Pst) is an economically devasting disease that is prominent in cereal crops such as wheat (Triticum aestivum). The fungal pathogen can cause approximately 30–70% losses in crop productivity and yields.
Manamele Dannies Mashabela+5 more
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To gain confidence in results of omic-data acquisitions, methods must be benchmarked using validated quality control materials. We report data combining both untargeted and targeted metabolomics assays for the analysis of four new human fecal reference ...
Raquel Cumeras+5 more
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Serum-Urine Matched Metabolomics for Predicting Progression of Henoch-Schonlein Purpura Nephritis
Henoch-Schonlein purpura nephritis (HSPN) is a common glomerulonephritis secondary to Henoch-Schonlein purpura (HSP) that affects systemic metabolism. Currently, there is a rarity of biomarkers to predict the progression of HSPN.
Qian Zhang+7 more
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