Results 61 to 70 of about 7,923 (211)

Primary Anylasis on the Methodology and Strategies for Studying Mechanisms of Acu-moxibustion by Using Metabonomics

针刺研究, 2011
Metabonomics is a newly emerging modern technology in the Post-genome era and has been being used widely in the study on modern Chinese medicine.But it have been rarely used in the study on acupuncture therapy.In the present paper,the authors introduce ...
GAO Jun, LIU Xu-guang, YAN Xian-zhong1, YU Shu-guang, WU Qiao-feng, DU Huai-bin, LIANG Fan-rong   +6 more
doaj   +2 more sources

Advances in the Application of Metabolomics in Cereal Foods

Shipin gongye ke-ji
Cereal foods are the primary source of daily energy, protein, and dietary fiber intake for humans. With the continuous improvement of people's living standards, cereal foods' nutritional value, safety, and food quality have attracted much attention ...
Qiqi FAN, Xiangxiang ZHAO, Ming WU, Xiang LI, Shuai ZHANG, Jiang YU, Xiaofei LIU, Na ZHANG   +7 more
doaj   +1 more source

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

Single nucleotide and copy number polymorphisms of the SULT1A1 gene in a South African Tswana population group

South African Journal of Science, 2011
Previous studies on gene mapping have firmly established variation in segments of the DNA structure amongst different population groups. SULT1A1 is one of four SULT1A genes that maps to the short arm of chromosome 16, and this area has been shown to ...
Hlengiwe Mbongwa, Petrus Pretorius, Annemarie Kruger, Gerhard Koekemoer, Carolus Reinecke   +4 more
doaj  

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, Volume 7, Issue 4, August 2026.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Network-based pharmacology-based research on the effect and mechanism of the Hedyotis diffusa–Scutellaria Barbata pair in the treatment of hepatocellular carcinoma

Scientific Reports
The Hedyotis diffusa–Scutellaria officinalis pair (HD–SB) has therapeutic effects on a variety of cancers. Our study was to explore the mechanism of HD–SB in the treatment of hepatocellular carcinoma (HCC).
Changmiao Hou, Xiao Wen, Shifan Yan, Xiaoxiao Gu, Yu Jiang, Fang Chen, Yanjuan Liu, Yimin Zhu, Xiehong Liu   +8 more
doaj   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, Volume 13, Issue 42, 28 July 2026.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Advances in separation science applied to metabonomics

, 2008
Metabonomics focuses on metabolite profile changes in diverse living systems caused by a biological perturbation. These metabolite signatures can be achieved with techniques such as gas chromatography, high-performance liquid chromatography (ultra-high ...
Legido-Quigley, Cristina
core   +1 more source

Metabonomics in Drug risk Assessment [PDF]

, 2013
Metabonomics in drug risk assessment J.-M. Colet Department of Human Biology & Toxicology / UMons In the last decade, the metabonomics approach has been extensively applied in the pharmaceutical industry in order to accelerate drug development. Most of
Colet, Jean-Marie
core   +1 more source

Momordica charantia Ethanol Extract Alleviates Type 2 Diabetes Mellitus Through Gut Microbiota‐Derived Tryptophan Metabolism

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Type 2 diabetes mellitus (T2DM) poses a significant global public health challenge. Dietary interventions rich in plant extracts of bioactive substances show promise for alleviating the symptoms of Type 2 diabetes. Previous studies have reported the excellent efficiency of Momordica charantia L.
Qiaojun Huang, Ziqing Liang, Yanting Zeng, Chenyan Yao, Jingtong He, Yong Cao, Yunjiao Chen   +6 more
wiley   +1 more source