Results 71 to 80 of about 7,923 (211)
A GC-based metabonomics investigation of type 2 diabetes by organic acids metabolic profile
, 2007 "Metabonomics" method requires the development of rapid, advanced analytical tools and GC will play an important role for its special advantage. In this study we shown the application of GC-based metabonomics to investigate the control and type 2 ...
Yuan, Kailong +5 more
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Twenty years of metabonomics: so what has metabonomics done for toxicology? [PDF]
, 2019 In 1999 the journal Xenobiotica published a perspective article detailing the new concept of metabonomics and its application to toxicology. The approach was to apply analytical chemistry techniques, and in particular 1 H NMR spectroscopy, to profile ...
Griffin, Julian L
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Drug Design, Development and Therapy, 2023 Li Chen,1 Wang-Yang Xu,2 Hao Chen,1 Yan-Quan Han,1 Yu-Ting Zhang1 1The First Affiliated Hospital, Anhui University of Traditional Chinese Medicine, Hefei, People’s Republic of China; 2The College of Pharmacy, Anhui University of Traditional Chinese ...
Chen L, Xu WY, Chen H, Han YQ, Zhang YT
doaj
MedComm, Volume 7, Issue 7, July 2026.Proposed mechanism of middle‐dose sorafenib modulates redox homeostasis via c‐Raf/HSP90/G6PD axis to attenuate hepatic IRI. This study demonstrates that middle‐dose sorafenib mitigates hepatic IRI through the c‐Raf/HSP90/G6PD axis to enhance pentose phosphate pathway‐mediated antioxidant defense and redox homeostasis, thereby alleviating inflammatory ...
Fengqiang Gao +13 more
wiley +1 more source
CURRENT ISSUES AND STRATEGY FOR METABONOMICS USING GC×GC-TOFMS
, 2008 CURRENT ISSUES AND STRATEGY FOR METABONOMICS USING GC×GC ...
许国旺, 李响, 孔宏伟, 路鑫
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The Application of Chromatography-Mass Spectrometry: Methods to Metabonomics
, 2009 The widespread availability, suitability, and high sensitivity of chromatogrophy-mass spectrometry for chemical profiling analysis of multi-component biosamples are demonstrated by the comprehensive analysis of metabolites in all kind of biofluids or ...
Zhao, Chunxia +5 more
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AntioxidantsCognitive impairment (CI) causes severe impairment of brain function and quality of life of patients, which brings a great burden to society. Cerebral hypoxia is an important factor in the pathogenesis of CI.
Zhen Li +8 more
doaj +1 more source
Aging Cell, Volume 25, Issue 7, July 2026.Oxidative stress induces GLS2‐dependent IL‐1β secretion in senescent macrophages, promoting SCC invasion through the IL‐1β/IL‐1R2 axis. Targeting IL‐1β suppresses invasion more effectively than GLS2 inhibition, highlighting a potential therapeutic strategy for SCC.
Shimeng Wang +7 more
wiley +1 more source
LC-MS based Metabonomics: Effect of Preanalytical Procedures
, 2010 LC-MS based Metabonomics: Effect of Preanalytical ...
陈世礼 +6 more
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Research progress on biomarkers of traumatic brain injury
Animal Models and Experimental Medicine, Volume 9, Issue 6, Page 1065-1104, June 2026.Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen +8 more
wiley +1 more source