Results 121 to 130 of about 37,318 (237)
Presumed TP53 mosaicism: variants detected using a NGS hereditary cancer multigene panel [PDF]
Aims/Context: NGS multigene panels are routinely used to identify germline pathogenic variants in cancer susceptibility genes. In addition, NGS allows the identification of low-level mosaicism events that may not be detectable by conventional Sanger ...
Gonçalves, João +5 more
core
ABSTRACT Background Buccinator myomucosal flaps (BMFs) have been proposed as a reconstructive solution for defects of the tongue and oral floor; however, their harvest requires preservation of the facial artery and vein. This study aimed to evaluate the oncologic safety of this approach compared with free fasciocutaneous flaps (FFF).
Luigi Angelo Vaira +24 more
wiley +1 more source
Bowel obstruction caused by intraluminal colorectal cancer metastasis to the small bowel is a very rare event. Clinical symptoms are nonspecific and vary greatly. Most cases are diagnosed as metachronous metastasis after primary curative cancer treatment.
M. Fickenscher +2 more
doaj +1 more source
What's New? Patients with esophageal or gastroesophageal junction (GEJ) cancer with residual disease after treatment with neoadjuvant chemoradiotherapy (nCRT) and resection frequently experience poor survival. Improvements in outcome, however, may be possible using adjuvant treatment with nivolumab.
Rob H. A. Verhoeven +9 more
wiley +1 more source
Background/Aims : To identify the risk factors for metachronous gastric neoplasms in patients who underwent an endoscopic resection of a gastric neoplasm.
doaj +1 more source
Simultaneous Head and Neck and Lung Cancers: Implications and Therapeutic Management Timing
ABSTRACT Objectives This study aims to describe the characteristics of patients with simultaneous head and neck squamous cell carcinomas (HNSCCs) and lung cancer and to assess the impact of diagnosis‐to‐treatment interval (DTI) and treatment choices on outcomes. Design and Setting A bicentric retrospective observational study conducted between 2003 and
Dario Ebode +9 more
wiley +1 more source
Abstract Background The expansion of treatment options for prostate cancer (PC) has improved disease‐specific and overall survival outcomes but has also raised questions about the optimal level of treatment needed for patients based on their individual prognosis and accounting for potential toxicity, incorporating quality of life considerations ...
Rana R. McKay +18 more
wiley +1 more source
Experiences of metastatic prostate cancer patients with a mainstream genetic testing pathway
What's new? Germline genetic testing can direct cancer patients towards more optimal treatment options and relatives towards targeted cancer screening or preventive measures. In the case of prostate cancer, many patients are eligible for such testing, though little is known about its psychosocial impacts.
Michiel Vlaming +21 more
wiley +1 more source
ABSTRACT Background In recent years, the incidence of early upper gastric cancer has increased, leading to a wider adoption of proximal gastrectomy (PG) as a possible treatment option. PG is preferred over total gastrectomy (TG) due to its superior postoperative nutritional status and improved surgical safety.
Linchuan Li +6 more
wiley +1 more source

