Intratumoral bacteria engineered for tumor therapy
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang +7 more
wiley +1 more source
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
Host immunogenetic variation and gut microbiome functionality in a wild vertebrate population. [PDF]
Lee CZ +6 more
europepmc +1 more source
Abstract Background The aim of this study is to determine whether the timing of metronidazole (MTZ) and amoxicillin (AMX) administration, relative to scaling and root planing (SRP), influences the clinical and microbiological outcomes of periodontal treatment.
Daiane Fermiano +10 more
wiley +1 more source
Diagnostic sensitivity and specificity of metagenomic sequencing and qPCR for detection of viruses associated with bovine respiratory disease estimated using Bayesian latent class models. [PDF]
Donbraye E +10 more
europepmc +1 more source
This meta‐analysis suggests that NGS of sonicate fluid demonstrates higher sensitivity compared to NGS of synovial fluid or periprosthetic tissue, while maintaining strong specificity, making it valuable for detecting infection. Periprosthetic tissue NGS demonstrated exceptional specificity and acceptable sensitivity, making it valuable for confirming ...
Lina Wang +6 more
wiley +1 more source
Correlation between gut microbiota and their metabolites and the efficacy of chemotherapy combined with immunotherapy for extensive-stage small cell lung cancer. [PDF]
Song W +5 more
europepmc +1 more source
Principles and Practice Guidelines of Microbiota Medicine: Statements From the CHINAGUT Conference
The 2025 CHINAGUT Conference convened a panel of 48 clinicians from 39 hospitals in 5 countries to develop 15 key statements, aimed at providing clinicians, educators, and healthcare administrators with a comprehensive framework to advance education, clinical practice, research, and public popularization in microbiota medicine.
Faming Zhang +52 more
wiley +1 more source
ABSTRACT Honey bees (Apis mellifera) are vital pollinators in fruit‐producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes.
Huan Zhong +25 more
wiley +1 more source
A novel analysis workflow for simultaneous parsing prokaryotic and eukaryotic microbial genes from metagenomes. [PDF]
Zhang W, Zheng Y, Han G, He X.
europepmc +1 more source

