Results 11 to 20 of about 33,548 (283)

Pathogenic Detection by Metagenomic Next-Generation Sequencing in Osteoarticular Infections [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Objectives: To evaluate metagenomic next-generation sequencing (mNGS) as a diagnostic tool in detecting pathogens from osteoarticular infection (OAI) samples.Methods: 130 samples of joint fluid, sonicate fluid, and tissue were prospectively collected ...
Zi-da Huang   +8 more
doaj   +3 more sources

Anncaliia algerae Microsporidiosis Diagnosed by Metagenomic Next-Generation Sequencing, China

open access: yesEmerging Infectious Diseases, 2022
We report a case of Anncaliia algerae microsporidia infection in an immunosuppressed kidney transplant recipient in China. Light microscopy and transmission electron microscopy initially failed to identify A.
Chen Liu   +3 more
doaj   +3 more sources

Application of Metagenomic Next-Generation Sequencing in Mycobacterium tuberculosis Infection

open access: yesFrontiers in Medicine, 2022
The fight against Mycobacterium tuberculosis (MTB) has been going on for thousands of years, while it still poses a threat to human health. In addition to routine detections, metagenomic next-generation sequencing (mNGS) has begun to show presence as a ...
Yaoguang Li   +7 more
doaj   +3 more sources

Clinical application of metagenomic next-generation sequencing in tuberculosis diagnosis

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
ObjectiveThe purpose of this study was to evaluate the clinical diagnostic value of metagenomic next-generation sequencing (mNGS) for tuberculosis (TB).MethodsThis retrospective study included 52 patients with suspected TB infection.
Ying Liu   +7 more
doaj   +3 more sources

Direct detection and identification of periprosthetic joint infection pathogens by metagenomic next-generation sequencing

open access: yesScientific Reports, 2023
This study assessed the application of metagenomic next-generation sequencing in pathogen detection of periprosthetic joint infections. A total of 95 cases who previously had undergone hip and knee replacement undergoing revision from January 2018 to ...
Linjie Hao   +7 more
doaj   +1 more source

The microbiological diagnostic performance of metagenomic next-generation sequencing in patients with sepsis

open access: yesBMC Infectious Diseases, 2021
Background In this study, we aimed to perform a comprehensive analysis on the metagenomic next-generation sequencing for the etiological diagnosis of septic patients, and further to establish optimal read values for detecting common pathogens. Methods In
Di Ren   +18 more
doaj   +1 more source

Trends and Developments in the Detection of Pathogens in Central Nervous System Infections: A Bibliometric Study

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
IntroductionRapid, sensitive, and specific laboratory assays are critical for the diagnosis and management of central nervous system (CNS) infections. The purpose of this study is to explore the intellectual landscape of research investigating methods ...
Yangyang Guo   +6 more
doaj   +1 more source

Polymicrobial Anaerobic Meningitis Detected by Next-Generation Sequencing: Case Report and Review of the Literature

open access: yesFrontiers in Medicine, 2022
BackgroundAnaerobic meningitis is a severe central nervous system infection associated with significant neurological sequelae and high mortality. However, the precise detection of causative pathogen(s) remains difficult because anaerobic bacteria are ...
Xiaoqiang Li   +4 more
doaj   +1 more source

Epileptic Seizure after Use of Moxifloxacin in Man with Legionella longbeachae Pneumonia

open access: yesEmerging Infectious Diseases, 2020
Legionellosis caused by Legionella longbeachae is diagnosed mainly by PCR. We report a case of L. longbeachae infection in mainland China, which was diagnosed by metagenomic next-generation sequencing, in a man who developed an epileptic seizure after ...
Jin-Yong Wang   +3 more
doaj   +1 more source

Metagenomic Next-Generation Sequencing for Periprosthetic Joint Infections

open access: yesCureus, 2023
Periprosthetic joint infection (PJI) after arthroplasty is a major complication, which requires significant resources, resulting in high costs for the medical system. In recent years, significant progress has been made in the diagnosis and treatment of periprosthetic infections, the identification of the pathogen being the central element in the ...
Cretu, Bogdan   +6 more
openaire   +2 more sources

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