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Engineered surface strategies to manage dental implant‐related infections
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza +7 more
wiley +1 more source
Correction: Assessment of Metagenomic Assembly Using Simulated Next Generation Sequencing Data
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Neurocysticercosis: diagnosis via metagenomic next-generation sequencing
Practical Neurology, 2023A 68-year-old Brazilian woman had 3 months of progressive fatigue, difficulty walking and 18 kg weight loss. On examination, there was gait apraxia and executive dysfunction. MR scan of brain showed communicating hydrocephalus and a cerebrospinal fluid showed 105 white cells/µL (≤5), predominantly lymphocytes, protein of 1.35 g/L (0.15–0.45) and the ...
Denison Alves, Pedrosa +6 more
openaire +2 more sources
METAGENOMIC NEXT-GENERATION SEQUENCING DETECTS PATHOGENS IN ENDOPHTHALMITIS PATIENTS
Retina, 2022Purpose: To investigate the utility of metagenomic next-generation sequencing (mNGS) in identifying the pathogens in endophthalmitis. Methods: In this prospective study, 36 cases of endophthalmitis were recruited. All patients received surgical treatment and intraocular drug lavage.
Junfeng, Zhu +9 more
openaire +2 more sources
Adenovirus metagenomic next-generation sequencing
2023We detected the adenovirus infection in nasopharyngeal swab samples from patients with respiratory tract infection. mNGS was performed on NextSeq 550 and GenoLab M sequencing platforms to study viral phylogenetics and recombination.
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Metagenomic Next-Generation Sequencing in Clinical Microbiology
Clinical Microbiology Newsletter, 2020Abstract Identification of causative pathogens in infectious disease is a critical component of health care, as infectious diseases continue to be a leading cause of mortality and morbidity worldwide. In addition, the detection of drug resistance by traditional and novel antimicrobial susceptibility testing methods is becoming ever more important as ...
George S. Watts, Bonnie L. Hurwitz
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Metagenomics Using Next-Generation Sequencing
2014Traditionally, microbial genome sequencing has been restricted to the small number of species that can be grown in pure culture. The progressive development of culture-independent methods over the last 15 years now allows researchers to sequence microbial communities directly from environmental samples.
Bragg,Lauren, Tyson, Gene W.
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Exploring Metagenomes Using Next-Generation Sequencing
2017Metagenomics or community genomics refers to the study of genomic DNA of any culture-independent analysis of microbial communities. Non-culturable microbial groups represent the huge majority of global microorganisms. Microbial populations present in every biological niche even humans body carry 10 times more bacterial cells and 100 times more ...
Jalpa R. Thakkar +2 more
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Rapid detection of pulmonary nocardiosis by metagenomic next generation sequencing
Diagnostic Microbiology and Infectious Disease, 2023We retrospectively analyzed 3 cases of pulmonary nocardiosis. Patients were identified by metagenomic next generation sequencing (mNGS) in the First Affiliated Hospital of Soochow University, from January 2019 to April 2022. All patients had underlying diseases, and were in immunocompromised state, with membranous nephropathy, acute lymphoblastic ...
Lirong Gao +4 more
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Metagenomic Next-Generation Sequencing of Viruses Infecting Grapevines
2015Next-generation sequencing (NGS) technologies, for the first time, provide a truly "complete" representation of the viral (and other) pathogens present in a host organism. This is achieved in an unbiased way, and without any prior biological or molecular knowledge of these pathogen(s).
Johan T, Burger, Hans J, Maree
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