Results 101 to 110 of about 58,396 (229)

Emergence and Polyclonal Dissemination of blaNDM-7–Carrying InX3 Plasmid in Enterobacter cloacae Complex, France, 2021–2023

Emerging Infectious Diseases
Among 3,367 New Delhi metallo-β-lactamase–producing Enterobacterales isolates collected in France during 2021–2023, we found the blaNDM-7 gene systematically localized on 2 closely related InX3 plasmids known to harbor antimicrobial resistance and ...
Ines Rezzoug, Delphine Girlich, Aurelien Birer, Richard Bonnet, Josephine Poiraud, Pierre Bogaerts, Cécile Emeraud, Laurent Dortet   +7 more
doaj   +1 more source

Metallo-β-lactamase and genetic diversity of Pseudomonas aeruginosa in intensive care units in Campo Grande, MS, Brazil

Brazilian Journal of Infectious Diseases, 2011
Infection by Pseudomonas aeruginosa has spread worldwide, with limited options for treatment. The purpose of this study was to investigate metallo-β-lactamase-producing P.
Ana Claudia Souza Rodrigues, M.D., Marilene Rodrigues Chang, Ph.D., Gabriela Dorn Nóbrega, Mayara Souza Rodrigues, Nadia Cristina Pereira Carvalho, Beatriz Garcia Gomes, Dênio Lopes de Almeida, Karyne Rangel Carvalho, M.D., Marise Dutra Asensi, Ph.D.   +8 more
doaj   +1 more source

Plasmid-Borne AFM Alleles in Pseudomonas aeruginosa Clinical Isolates from China

Microbiology Spectrum, 2022
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a pathogen of global concern due to the fact that therapeutic drugs are limited. Metallo-β-lactamase (MBL)-producing P. aeruginosa has become a critical part of CRPA.
Minhua Chen, Heng Cai, Yue Li, Nanfei Wang, Piaopiao Zhang, Xiaoting Hua, Yunsong Yu, Renhua Sun   +7 more
doaj   +1 more source

Metallo-β-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism

Biomolecules, 2020
β-Lactam antibiotics are the most widely prescribed antibacterial drugs due to their low toxicity and broad spectrum. Their action is counteracted by different resistance mechanisms developed by bacteria.
A.R.O. Palacios, M. Rossi, Graciela Mahler, A. Vila   +3 more
semanticscholar   +1 more source

Antibiotic Resistance, Biofilm Genes, and smeDEF Efflux Pump in Clinical Stenotrophomonas maltophilia Isolates From Iran

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Iranian clinical Stenotrophomonas maltophilia isolates showed high susceptibility to trimethoprim/sulfamethoxazole, minocycline, and levofloxacin, but marked resistance to ceftazidime and ticarcillin‐clavulanate, alongside widespread biofilm production and resistance genes.
Haneen Fadhil Jasim, Nisreen Salah Majeed, Asmaa A. Salam, Rania Hameed Hamad, Yeganeh Behrouzi, Erta Rajabi, Razieh Shahbazi   +6 more
wiley   +1 more source

Spectroscopic Studies on \u3cem\u3eArabidopsis\u3c/em\u3e ETHE1, a Glyoxalase II-like Protein [PDF]

, 2008
ETHE1 (ethylmalonic encephalopathy protein 1) is a β-lactamase fold-containing protein that is essential for the survival of a range of organisms. In spite of the apparent importance of this enzyme, very little is known about its function or biochemical ...
Bennett, Brian, Crowder, Michael W., Holdorf, Meghan M., Makaroff, Christopher A.   +3 more
core   +1 more source

Rapid detection of carbapenemase-producing Enterobacteriaceae. [PDF]

, 2012
To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of a carbapenem, imipenem.
Dortet, L, Nordmann, P, Poirel, L
core   +1 more source

Design of Primers for Detection and Typing of β-Lactamase Genes from Pathogenic Species of Burkholderia

Проблемы особо опасных инфекций, 2012
The set of oligonucleotide primers was designed to identify β-lactam-resitance determinats in isolates of pathogenic Burkholderia using PCR. Simultaneously identified was certain molecular class of detected β-lactamases.
A. V. Romanova, I. B. Zakharova, V. S. Zamaraev, D. V. Viktorov   +3 more
doaj   +1 more source

Evaluation of the EDTA-Modified Carbapenem Inactivation Method for Detecting Metallo-β-Lactamase-Producing Pseudomonas aeruginosa

Journal of Clinical Microbiology, 2020
The prevalence of carbapenem-resistant Pseudomonas aeruginosa is increasing. Identification of carbapenemase-producing P. aeruginosa will have therapeutic, epidemiological, and infection control implications.
C. Gill, Maxwell J. Lasko, T. Asempa, D. Nicolau   +3 more
semanticscholar   +1 more source

Antibacterial Activity of Estragole From Ocimum tenuiflorum, and Tagetes lucida and Synergistic Effect With Meropenem and Tobramycin Against Multidrug‐ and Extensively Drug‐Resistant (MDR‐XDR) Gram‐Negative Bacteria

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study reveals estragole's bactericidal activity against MDR/XDR Gram‐negative pathogens. Synergy with meropenem and tobramycin was observed in > 88% of strains, reducing antibiotic MICs up to 16‐fold. Estragole represents a promising therapeutic adjuvant to enhance antibiotic efficacy and combat antimicrobial resistance.
María Araque, Luis B. Rojas
wiley   +1 more source