Results 81 to 90 of about 893,574 (181)

Design of Primers for Detection and Typing of β-Lactamase Genes from Pathogenic Species of Burkholderia

open access: yesПроблемы особо опасных инфекций, 2012
The set of oligonucleotide primers was designed to identify β-lactam-resitance determinats in isolates of pathogenic Burkholderia using PCR. Simultaneously identified was certain molecular class of detected β-lactamases.
A. V. Romanova   +3 more
doaj   +1 more source

Occurrence and Distribution of Environmental Pseudomonas aeruginosa From Hospitals in Bangladesh Reveals Diverse Strain Families, Multidrug Resistance, and Biofilm Formation

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Environmental reservoirs in Bangladeshi hospitals harbor phylogenetically diverse, multidrug‐resistant Pseudomonas aeruginosa with extensive biofilm‐forming capacity and class 1 integron‐associated resistance genes. These findings highlight hospital environments as persistent sources of antimicrobial resistance dissemination and underscore the need for
S. M. Kador   +9 more
wiley   +1 more source

Potential inhibitors designed against NDM-1 type metallo-β-lactamases: an attempt to enhance efficacies of antibiotics against multi-drug-resistant bacteria

open access: yesScientific Reports, 2017
NDM-1 and its variants are the most prevalent types of metallo-β-lactamases, hydrolyze almost all antibiotics of β-lactam group leading to multiple-drug resistance in bacteria.
Asad U. Khan   +4 more
doaj   +1 more source

Plant Defence Metabolite Detoxification by a Pathogenic Fungus Opens Necrotic Tissue to Diverse Bacteria in Arabidopsis thaliana

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Sclerotinia sclerotiorum, a devastating necrotrophic fungal pathogen of many crops, recruits a specific microbiome to necrotic, diseased leaf tissue. The interaction between plant formation and fungal degradation of aliphatic glucosinolate‐derived defence metabolites nearly completely controls this recruitment. ABSTRACT Foliar necrotic fungal pathogens
Shubhangi Sharma   +2 more
wiley   +1 more source

Progress toward inhibitors of metallo-β-lactamases

open access: yes, 2017
The global overuse of antibiotics has led to the emergence of drug-resistant pathogenic bacteria. Bacteria can combat β-lactams by expressing β-lactamases.
Ross P McGeary   +5 more
core   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

open access: yesAdvanced Science, Volume 13, Issue 38, 9 July 2026.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng   +11 more
wiley   +1 more source

Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors

open access: yesNature Communications, 2018
Metallo-β-lactamases (MBL) are zinc containing enzymes that cause resistance to β-lactam antibiotics. Here the authors show that the anti-Helicobacter pylori drug colloidal bismuth subcitrate inhibits MBLs by displacing the zinc ions with Bi(III), which ...
Runming Wang   +9 more
doaj   +1 more source

Genomic Insights Into Antimicrobial Resistance and Virulence of Enterococcus avium Strains From Bovine Mastitis in Some Selected Dairy Farms of Bangladesh

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
The graphical abstract outlines that samples from milk, faeces and soil were tested for Enterococcus avium using culture, PCR and genome sequencing.2. Overall, prevalence of E. avium was 56.3%, and 93.5% of isolates were multidrug‐resistant.3. Genomic analysis revealed six ARGs, 43–45 VFGs and 4–6 bacteriocins.4.
Monira Rahaman   +10 more
wiley   +1 more source

Structure and function of metallo-β-lactamases. Meet-the-Experts session “Structure, Function and Genetics of Metallo-β-Lactamases”.

open access: yes, 2011
Metallo-β-lactamases (Ambler’s class B, Bush-Jacoby’s classification group 3) are zinc-dependent enzymes able to hydrolyze a wide variety of β-lactam antibiotics, including oxyimino cephalosporins and carbapenems, while they are not inhibited by ...
DOCQUIER, JEAN DENIS
core   +1 more source

Identification and Genomic Analysis of the First Salmonella typhimurium Monophasic Variant 1,4,[5],12:i:‐ Isolate Harbouring a Chromosomally Integrated blaNDM‐5

open access: yesMicrobial Biotechnology, Volume 19, Issue 7, July 2026.
This study reports the first clinical isolate of the monophasic variant of Salmonella typhimurium (serotype 1,4,[5],12:i:‐) ST34 harbouring a chromosomally integrated blaNDM‐5. The ~11 kb resistance region is flanked by two directly oriented IS26 elements, forming an IS26‐composite transposon.
Shihan Zeng   +4 more
wiley   +1 more source

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