Results 81 to 90 of about 893,574 (181)
The set of oligonucleotide primers was designed to identify β-lactam-resitance determinats in isolates of pathogenic Burkholderia using PCR. Simultaneously identified was certain molecular class of detected β-lactamases.
A. V. Romanova +3 more
doaj +1 more source
Environmental reservoirs in Bangladeshi hospitals harbor phylogenetically diverse, multidrug‐resistant Pseudomonas aeruginosa with extensive biofilm‐forming capacity and class 1 integron‐associated resistance genes. These findings highlight hospital environments as persistent sources of antimicrobial resistance dissemination and underscore the need for
S. M. Kador +9 more
wiley +1 more source
NDM-1 and its variants are the most prevalent types of metallo-β-lactamases, hydrolyze almost all antibiotics of β-lactam group leading to multiple-drug resistance in bacteria.
Asad U. Khan +4 more
doaj +1 more source
Sclerotinia sclerotiorum, a devastating necrotrophic fungal pathogen of many crops, recruits a specific microbiome to necrotic, diseased leaf tissue. The interaction between plant formation and fungal degradation of aliphatic glucosinolate‐derived defence metabolites nearly completely controls this recruitment. ABSTRACT Foliar necrotic fungal pathogens
Shubhangi Sharma +2 more
wiley +1 more source
Progress toward inhibitors of metallo-β-lactamases
The global overuse of antibiotics has led to the emergence of drug-resistant pathogenic bacteria. Bacteria can combat β-lactams by expressing β-lactamases.
Ross P McGeary +5 more
core +1 more source
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng +11 more
wiley +1 more source
Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors
Metallo-β-lactamases (MBL) are zinc containing enzymes that cause resistance to β-lactam antibiotics. Here the authors show that the anti-Helicobacter pylori drug colloidal bismuth subcitrate inhibits MBLs by displacing the zinc ions with Bi(III), which ...
Runming Wang +9 more
doaj +1 more source
The graphical abstract outlines that samples from milk, faeces and soil were tested for Enterococcus avium using culture, PCR and genome sequencing.2. Overall, prevalence of E. avium was 56.3%, and 93.5% of isolates were multidrug‐resistant.3. Genomic analysis revealed six ARGs, 43–45 VFGs and 4–6 bacteriocins.4.
Monira Rahaman +10 more
wiley +1 more source
Metallo-β-lactamases (Ambler’s class B, Bush-Jacoby’s classification group 3) are zinc-dependent enzymes able to hydrolyze a wide variety of β-lactam antibiotics, including oxyimino cephalosporins and carbapenems, while they are not inhibited by ...
DOCQUIER, JEAN DENIS
core +1 more source
This study reports the first clinical isolate of the monophasic variant of Salmonella typhimurium (serotype 1,4,[5],12:i:‐) ST34 harbouring a chromosomally integrated blaNDM‐5. The ~11 kb resistance region is flanked by two directly oriented IS26 elements, forming an IS26‐composite transposon.
Shihan Zeng +4 more
wiley +1 more source

