Results 211 to 220 of about 32,111 (260)
Ligand‐Directed Modification of Active Matrix Metalloproteases: Activity‐based Probes with no Photolabile Group [PDF]
Angewandte Chemie - International Edition, 2021 International audienceActivity-based probes enable discrimination between the active enzyme and its inactive or inactivated counterparts. Since metalloproteases catalysis is non-covalent, activity-based probes targeting them have been systematically ...
Olivier Lequin +2 more
exaly +4 more sources
Whole-Genome Metalloproteases in the Wheat Sharp Eyespot Pathogen Rhizoctonia cerealis and a Role in Fungal Virulence [PDF]
International Journal of Molecular Sciences, 2022 Rhizoctonia cerealis is the causal agent of sharp eyespot, a devastating disease of cereal crops including wheat. Several metalloproteases have been implicated in pathogenic virulence, but little is known about whole-genome metalloproteases in R ...
Zengyan Zhang, Wenwu Ye, Feilong Guo
exaly +2 more sources
Correlation of serum and urinary matrix metalloproteases/tissue inhibitors of metalloproteases with subclinical allograft fibrosis in renal transplantation [PDF]
Transplant Immunology, 2014 Progressive interstitial fibrosis and tubular atrophy (IF/TA) is a leading cause of chronic allograft dysfunction. Increased extracellular matrix remodeling regulated by matrix metalloproteases (MMPs) and their inhibitors (TIMPs) has been implicated in ...
Denis Grandgirard +2 more
exaly +2 more sources
The clearance of misfolded proteins in neurodegenerative diseases by zinc metalloproteases: An inorganic perspective [PDF]
Coordination Chemistry Reviews, 2014 In recent years there has been a wide interest toward zinc metalloproteases involved in neurodegenerative diseases. Enzymes such as matrix metalloproteases, neprilysin, insulin degrading enzyme, etc. play a pivotal role in the homeostasis of peptides and
Gaetano Malgieri, Giuseppe Grasso
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Metalloproteases and the Degradome
2010Metalloproteases comprise a heterogeneous group of proteolytic enzymes whose main characteristic is the utilization of a metal ion to polarize a water molecule and perform hydrolytic reactions. These enzymes represent the most densely populated catalytic class of proteases in many organisms and play essential roles in multiple biological processes.
Alejandro P, Ugalde +4 more
openaire +2 more sources
Microbial metalloproteases and pathogenesis
Microbes and Infection, 2000Zinc metalloproteases produced by human pathogenic microorganisms show a wide variety of pathological actions. In local infections, the proteases cause necrotic or hemorrhagic tissue damage through digestion of structural components of the ground substance, and also form edematous lesions through generation of inflammatory mediators, while in systemic ...
S, Miyoshi, S, Shinoda
openaire +2 more sources
Active Metalloproteases of the A Disintegrin And Metalloprotease (ADAM) Family
Journal of Proteome Research, 2011The "a disintegrin and metalloproteases" (ADAMs) are membrane-anchored metzincins of the adamalysin subfamily. This review gives an overview over the biological function and structure of ADAMs focusing on members of the family that display proteolytic activity.
Klein, Theo, Bischoff, Rainer
openaire +3 more sources
Moschcowitz, Multimers, and Metalloprotease
New England Journal of Medicine, 1998In 1924, Dr. Eli Moschcowitz described the abrupt onset of petechiae and pallor, followed rapidly by paralysis, coma, and death, in a 16-year-old girl.1 Terminal arterioles and capillaries in the d...
openaire +2 more sources
Metalloproteases in gonad formation and ovulation
General and Comparative Endocrinology, 2021Changes in expression or activation of various metalloproteases including matrix metalloproteases (Mmp), a disintegrin and metalloprotease (Adam) and a disintegrin and metalloprotease with thrombospondin motif (Adamts), and their endogenous inhibitors (tissue inhibitors of metalloproteases, Timp), have been shown to be critical for ovulation in various
openaire +2 more sources
Metalloproteases of Leptospira
2021This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
openaire +1 more source