Results 201 to 210 of about 32,111 (260)

Porphyromonas gingivalis-Derived Virulence Lipids Accelerate Osteoclastogenesis Independently of High Mobility Group Box Protein-1 Canonical Signaling. [PDF]

Mol Oral Microbiol
Yamada C, Peng G, Johnson JA, Nusbaum A, Sanz N, AlQallaf H, Nichols F, Movila A.   +7 more
europepmc   +1 more source

Protein functional site annotation using local structure embeddings. [PDF]

Proc Natl Acad Sci U S A
Derry A, Tartici A, Altman RB.
europepmc   +1 more source

An Integrated Approach of Proteomic, Cheminformatic, and In Vitro Drug Screening to Identify Potential Therapeutic Targets of <i>Taenia solium</i> Cysticerci Proteases. [PDF]

ACS Omega
Kaur R, Rawat SS, Keshri AK, Arora N, Mehra P, Chaudhary A, Sharma S, Kumar R, Mishra A, Prasad A.   +9 more
europepmc   +1 more source

A Bifunctional Protease Cleaves the Leader Peptide in the Biosynthesis of Class I Microviridins. [PDF]

Chembiochem
Brüssow N, Scholz S, Stindt A, Wiebach V, Damaszek T, Süssmuth RD, Dittmann E, Baunach M.   +7 more
europepmc   +1 more source

Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses. [PDF]

Nat Commun
Banfield JF, Valentin-Alvarado LE, Shi LD, Robinson CM, Bamert RS, Coulibaly F, Barth ZK, Aylward FO, Schoelmerich MC, Lei S, Sachdeva R, Knott GJ.   +11 more
europepmc   +1 more source

Zinc Metalloprotease SlMEP1: An Essential Factor Required for Fungal Virulence in <i>Stemphylium lycopersici</i>. [PDF]

J Fungi (Basel)
Zhang D, Chi W, Li T, Wang C, Zhang J, Pan H, Qiao N, Li J, Sun X.   +8 more
europepmc   +1 more source

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Metalloproteases and inhibitors in arthritic diseases

Best Practice and Research in Clinical Rheumatology, 2001
Controlling degradation of the extracellular matrix is crucial in arthritic diseases such as osteoarthritis (OA) and rheumatoid arthritis (RA), as conventional treatments do not positively affect the structural properties of the articular tissues. Metalloproteases, a family of zinc-dependent enzymes, and more specifically the matrix metalloproteases ...
Jean-Pierre Pelletier, Johanne Martel-Pelletier, J P Pelletier   +2 more
exaly   +3 more sources

Metalloproteases and intracranial vascular lesions

Neurological Research, 1999
Recent studies have suggested that metalloproteinases (MMP) might be involved in the pathogenesis of cerebral aneurysm formation and rupture and that elevated serum levels of MMP may effectively be considered as possible markers of cerebrovascular malformations.
Paolo Gaetani, Riccardo Rodriguez Y Baena, V Grazioli   +2 more
exaly   +3 more sources

Inhibition of bacterial and human zinc-metalloproteases by bisphosphonate- and catechol-containing compounds [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Compounds containg catechol or bisphosphonate were tested as inhibitors of the zinc metalloproteases, thermolysin (TLN), pseudolysin (PLN) and aureolysin (ALN) which are bacterial virulence factors, and the human matrix metalloproteases MMP-9 and −14 ...
Cristina Campestre, Jan-Olof Winberg, Ingebrigt Sylte   +2 more
exaly   +3 more sources