Set of 13 representative metalloproteases of the MA Clan. [PDF]
, 2015 Set of 13 representative metalloproteases of the MA Clan.
Olga Iranzo (799057) +3 more
core +1 more source
Copper forms a PPII helix-like structure with the catalytic domains of bacterial zinc metalloproteases [PDF]
, 2023 The rapid spread of antibiotic-resistant bacteria continuously raises concerns about the future ineffectiveness of current antimicrobial treatments against infectious diseases.
Valensin, D +9 more
core +1 more source
Oxidative and Fibrinolytic Mechanisms: Two Important Processes to Consider in Platelet Storage
Turkish Journal of Hematology, 2023 Objective: Platelet-rich plasma (PRP) is used in multiple coagulation disorders. Its therapeutic effectiveness relies on technical procedures related to PRP procurement and preservation because free radicals induce platelet activation and aging.
Jesus Javier Garcia-Bañuelos +6 more
doaj +1 more source
Inhibition of bacterial and human zinc-metalloproteases [PDF]
, 2021 Antibiotic resistance is one of the major challenges in the present era and it is drastically increasing with the increase in time because of the overuse and misuse of antibiotics.
Chaulagain, Bibek
core
Modulating Matrix Metalloproteases and Inflammation in Huntington’s Disease [PDF]
, 2020 Huntington’s disease (HD) is a rare and incurable autosomal neurodegenerative disease affecting 1-10 in every 100,000 people in the world. There is no cure for HD and treatments available alleviate certain symptoms for short periods of time.
Lopez Ramirez, Alejandro
core +2 more sources
Frontiers in Immunology, 2019 A wide array of immune cells, including lymphocytes, is known to be present and to play a pathogenetic role in atherosclerotic lesions. However, limited information is currently available regarding the presence of Natural Killer (NK) cell subsets within ...
Irene Bonaccorsi +18 more
doaj +1 more source
Reviving the use of inhibitors of matrix metalloproteases in spinal cord injury: a case for specificity [PDF]
, 2023 At present, there are no restorative therapies in the clinic for spinal cord injury, with current treatments offering only palliative treatment options.
Zubair Ahmed, Ahmed, Zubair; id_orcid
core +1 more source
Identification of membrane proteins regulated by ADAM15 by SUSPECS proteomics
Frontiers in Molecular Biosciences, 2023 ADAM15 is a member of the disintegrin-metalloproteinase family of sheddases, which plays a role in several biological processes including cartilage homeostasis. In contrast with well-characterized ADAMs, such as the canonical sheddases ADAM17 and ADAM10,
Matteo Calligaris +12 more
doaj +1 more source
An Integrated Analysis of the Response of Colorectal Adenocarcinoma Caco-2 Cells to X-Ray Exposure
Frontiers in Oncology, 2021 Colorectal cancer is among the three top cancer types for incidence and the second in terms of mortality, usually managed with surgery, chemotherapy and radiotherapy.
Isabella Guardamagna +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source