Results 51 to 60 of about 32,111 (260)
Matrix Metallopeptidase 9 Expression in Tumoral and Marginal Tissues of Cholesteatoma [PDF]
ImmunoAnalysisBackground: Cholesteatoma, a serious, expanding otolaryngologic condition, is challenging to otolaryngologists worldwide. The purpose of the present study was to evaluate the expression of MMP-9 gene in cholesteatoma patients.
Yalda Jabbari Moghaddam +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Skeletal muscle cell hypertrophy induced by inhibitors of metalloproteases; myostatin as a potential mediator [PDF]
, 2001 Cell growth and differentiation are controlled in many tissues by paracrine factors, which often require proteolytic processing for activation. Metalloproteases of the metzincin family, such as matrix metalloproteases and ADAMs, recently have been shown ...
Clotilde Huet +5 more
core +1 more source
Facet joint degeneration in adolescent idiopathic scoliosis
JOR Spine, 2018 Adolescent idiopathic scoliosis (AIS) is a poorly understood deformity of the thoracolumbar spine which affects the intervertebral discs (IVDs) and the articular facet joints.
Daniel G. Bisson +6 more
doaj +1 more source
Revista Científica, 2021 Cuaima (Lachesis muta muta)(Lmm) is responsible for particular envenomations that occur mainly in people who are exploring forest areas, in logging activities, mining exploitation (mainly gold and diamonds) or indigenous people who live in small ...
Yuyibeth Montero +5 more
doaj +1 more source
Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines
Advanced Functional Materials, EarlyView.Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang +13 more
wiley +1 more source
Molecular analysis of astacin-like metalloproteases of Ostertagia ostertagi [PDF]
, 2005 In this study, we describe the Molecular analysis of zinc-metalloproteases from the abomasal nematode Ostertagia ostertagi which were exclusively recognized by local antibodies of immune cattle. Full-length or partial coding sequences of 4 different zinc-
I. VERCAUTEREN +11 more
core +1 more source
Exploring the Potential Role of ADAM 17 and ADAM 22 in the Etiology of Autism Spectrum Disorders
Brain Sciences, 2023 Background: Autism spectrum disorder (ASD) encompasses a group of disorders characterized by difficulties with social interaction and repetitive behavior. The condition is supposed to originate from early shifts in brain development, while the underlying
Sarah H. Al-Mazidi +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Metalloproteases of the Inner Mitochondrial Membrane [PDF]
Biochemistry, 2017 The inner mitochondrial membrane (IM) is among the most protein-rich cellular compartments. The metastable IM subproteome where the concentration of proteins is approaching oversaturation creates a challenging protein folding environment with a high probability of protein malfunction or aggregation.
Roman M. Levytskyy +2 more
openaire +2 more sources