Results 51 to 60 of about 24,294 (246)

Symptomatic Carotid Atherosclerotic Plaques Are Associated With Increased Infiltration of Natural Killer (NK) Cells and Higher Serum Levels of NK Activating Receptor Ligands

Frontiers in Immunology, 2019
A wide array of immune cells, including lymphocytes, is known to be present and to play a pathogenetic role in atherosclerotic lesions. However, limited information is currently available regarding the presence of Natural Killer (NK) cell subsets within ...
Irene Bonaccorsi, Irene Bonaccorsi, Domenico Spinelli, Claudia Cantoni, Claudia Cantoni, Chiara Barillà, Narayana Pipitò, Claudia De Pasquale, Daniela Oliveri, Daniela Oliveri, Riccardo Cavaliere, Riccardo Cavaliere, Riccardo Cavaliere, Paolo Carrega, Paolo Carrega, Filippo Benedetto, Guido Ferlazzo, Guido Ferlazzo, Guido Ferlazzo   +18 more
doaj   +1 more source

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family [PDF]

, 2015
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that have diverse roles in tissue morphogenesis and patho-physiological remodeling, in ...
A Colige, A Didangelos, A Luque, A Moncada-Pazos, A Noel, A Tan Ide, AC Jonsson-Rylander, AC Nicholson, AJ Fosang, B Joe, BH Koo, BH Koo, BV Nusgens, C Casal, C Esselens, C Gendron, C Kintakas, C Lopez-Otin, C Ricciardelli, CB Kern, CG Viloria, CH Mjaatvedt, CJ Liu, CJ Liu, CL Jacobi, CM Dancevic, CN Brocker, CR Flannery, D Wagsater, DL Russell, DL Silver, DR Edwards, DR McCulloch, DT Jones, Dylan R Edwards, EA Lin, EC Arner, ED Karagiannis, EM Majerus, F Guo, F Vazquez, FG Brunet, FX Gomis-Ruth, FX Gomis-Ruth, G Gao, G Gao, G Hashimoto, G Murphy, GC Choi, GE Lind, GG Levy, GJ Wayne, Grant N Wheeler, H Enomoto, H Jin, H Stanton, H Stanton, HL Lung, HM Brown, I Abbaszade, I Peluso, Ines Desanlis, J Dubail, J Dubail, J Felsenstein, J Hofsteenge, J Huxley-Jones, J Huxley-Jones, J Morales, JA Pyun, JC Adams, JC Rodriguez-Manzaneque, JC Rodriguez-Manzaneque, JC Rodriguez-Manzaneque, JD Sandy, JM Longpre, K Demircan, K Fujikawa, K Gopalakrishnan, K Kuno, K Kuno, K Stankunas, K Tamura, K Yamamoto, K Yamamoto, L Angerer, L Faivre, L Mittaz, L Mosyak, L Troeberg, L Troeberg, L Troeberg, L Wagstaff, LA Collins-Racie, LE Dupuis, LM Ricketts, M Cudic, M Hour El, M Kashiwagi, M Krampert, M Llamazares, MA Aldahmesh, MD Tortorella, MN Vankemmelbeke, N Dagoneau, N Hattori, N Rocks, N Rocks, N Stupka, NH Lim, NV Lee, NV Lee, P Wang, PH Lo, PJ Koshy, PS Chockalingam, R Kelwick, RC Salter, RH Song, Richard Kelwick, RL Robker, RP Somerville, RP Somerville, RS Patel, S Abdul-Majeed, S Gerhardt, S Kumar, S Kumar, S Nandadasa, S Porter, S Porter, SS Apte, SS Glasson, T Fontanil, T Shindo, TN Wight, U Auf Dem Keller, W Du, W Zeng, WE Kutz, WM Wang, X Lu, X Pu, XL Zheng, YJ Liu, YP Hsu   +145 more
core   +1 more source

ADAM10 Localization in Temporomandibular Joint Disk with Internal Derangement: An Ex Vivo Immunohistochemical Study [PDF]

, 2016
The purpose of this study was to determine the presence of ADAM10 in temporomandibular joint disk with internal derangement. Twenty-five paraffin blocks of displaced temporomandibular joint (TMJ) disk specimens from earlier investigations were retrieved ...
Almeida, Luis Eduardo, Castrogiovanni, Paola, Chiarenza, Giovanni Paolo Salvatore, Imbesi, Rosa, Leonardi, Rosalia, Loreto, Carla, Musumeci, Giuseppe, Ruggeri, Alessandra   +7 more
core   +2 more sources

Identification of membrane proteins regulated by ADAM15 by SUSPECS proteomics

Frontiers in Molecular Biosciences, 2023
ADAM15 is a member of the disintegrin-metalloproteinase family of sheddases, which plays a role in several biological processes including cartilage homeostasis. In contrast with well-characterized ADAMs, such as the canonical sheddases ADAM17 and ADAM10,
Matteo Calligaris, Matteo Calligaris, Chun Y. Yang, Simone Bonelli, Simone Bonelli, Donatella Pia Spanò, Donatella Pia Spanò, Stephan A. Müller, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Linda Troeberg, Simone D. Scilabra   +12 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

An Integrated Analysis of the Response of Colorectal Adenocarcinoma Caco-2 Cells to X-Ray Exposure

Frontiers in Oncology, 2021
Colorectal cancer is among the three top cancer types for incidence and the second in terms of mortality, usually managed with surgery, chemotherapy and radiotherapy.
Isabella Guardamagna, Leonardo Lonati, Monica Savio, Lucia A. Stivala, Andrea Ottolenghi, Giorgio Baiocco   +5 more
doaj   +1 more source

Components of cell-matrix linkage as potential new markers for prostate cancer [PDF]

, 2011
Prostate cancer is one of the most common tumor diseases worldwide. Often being non-aggressive, prostate tumors in these cases do not need immediate treatment.
Eble, Johannes Andreas, Navdaev, Alexey
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Matrix Metallopeptidase 9 Expression in Tumoral and Marginal Tissues of Cholesteatoma [PDF]

ImmunoAnalysis
Background: Cholesteatoma, a serious, expanding otolaryngologic condition, is challenging to otolaryngologists worldwide. The purpose of the present study was to evaluate the expression of MMP-9 gene in cholesteatoma patients.
Yalda Jabbari Moghaddam, Masoud Naderpour Germi, Shabnam Noei Alamdary, Milad Emami, Dariush Shanehbandi, Saiedeh Razi Soofiyani   +5 more
doaj   +1 more source

Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases [PDF]

, 2017
Thiolutin is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Its biological targets are not known. We show that reduced thiolutin is a zinc chelator that inhibits the JAB1/MPN/Mov34 (JAMM) domain–containing ...
A Jimenez, A Joshi, A Nijnik, AC Diernfellner, Albert A Bowers, Amy E Palmer, Anton Shostak, Axel Diernfellner, B Langmead, B Li, B Sobhian, B Wang, C Dani, C Perez, DJ Tipper, DM Duda, E Malzahn, E Meulmeester, E Zeqiraj, EJ Worden, EM Cooper, F Cesbron, Frauke Melchior, GA Collins, GA Cope, GA Cope, GG Khachatourians, H Wang, Herbert Tschochner, Ibrahim Avi Cemel, J Bonnet, J Grigull, J Li, J McCullough, J Roza, JI Belle, Jing Li, JV Geisberg, K Minamiguchi, Kyle P Carter, L Davidson, Linda Lauinger, M Agromayor, M Görl, M Knop, M Vera, Michael Brunner, MS Dai, N Sivasubramanian, N Wei, Nati Ha, Nicolas Stankovic-Valentin, P D'Arcy, P Merkl, P Zhu, PG Richardson, Philipp E Merkl, R Cao, R Verma, Raymond J Deshaies, RJ Deshaies, S Dai, S Schulz, Simon Obermeyer, T Hideshima, T Schafmeier, Tobias Schafmeier, V Nandakumar, V Pelechano, W Zhou, Walter J Wever, XX Jiang, Y Jia, Y Sato, Yaru Zhang   +74 more
core   +3 more sources