Hierarchically-structured metalloprotein composite coatings biofabricated from co-existing condensed liquid phases [PDF]
The mussel byssus cuticle is a wear-resistant and extensible metalloprotein composite. Here, the authors probed the cuticle nanostructure and composition before, during and after fabrication revealing a crucial role of metal-binding proteins that self ...
Franziska Jehle+5 more
doaj +4 more sources
MetalProGNet: a structure-based deep graph model for metalloprotein-ligand interaction predictions. [PDF]
Metalloproteins play indispensable roles in various biological processes ranging from reaction catalysis to free radical scavenging, and they are also pertinent to numerous pathologies including cancer, HIV infection, neurodegeneration, and inflammation.
Jiang D+16 more
europepmc +2 more sources
Background Specific targeting ability and good cell penetration are two critical requirements of tumor-targeted delivery systems. In the present work, we developed a novel matrix metalloprotein-triggered, cell-penetrating, peptide-modified, star-shaped ...
Fangyuan Guo+10 more
doaj +2 more sources
Changing paradigms for the micronutrient zinc, a known protein cofactor, as a signal relaying also cellular redox state [PDF]
The micronutrient zinc (Zn) is often poorly available but toxic when present in excess, so a tightly controlled Zn homoeostasis network operates in all organisms. This review summarizes our present understanding of plant Zn homoeostasis.
Ute Krämer
doaj +2 more sources
Methanogenesis marker 16 metalloprotein is the primary coenzyme M synthase in Methanosarcina acetivorans. [PDF]
2-mercaptoethanesulfonate (Coenzyme M, CoM) is an organic sulfur-containing cofactor used for hydrocarbon metabolism in archaea and bacteria. In archaea, CoM serves as an alkyl group carrier for enzymes belonging to the alkyl-CoM reductase family ...
Grayson L Chadwick+3 more
doaj +2 more sources
Online immunocapture ICP-MS for the determination of the metalloprotein ceruloplasmin in human serum
Objective The human copper-protein ceruloplasmin (Cp) is the major copper-containing protein in the human body. The accurate determination of Cp is mandatory for the reliable diagnosis of several diseases.
Bogdan Bernevic+3 more
doaj +2 more sources
Investigation of the Ferredoxin’s Influence on the Anaerobic and Aerobic, Enzymatic H2 Production
Ferredoxins are metalloproteins that deliver electrons to several redox partners, including [FeFe] hydrogenases that are potentially a component of biological H2 production technologies.
Jamin Koo, Yeeun Cha
doaj +1 more source
Single‐atom catalysts (SACs) exhibit unparalleled atomic utilization and catalytic efficiency, yet it is challenging to modulate SACs with highly dispersed single‐atoms, mesopores, and well‐regulated coordination environment simultaneously and ultimately
Jieying Liang+13 more
semanticscholar +1 more source
Copper Cytotoxicity: Cellular Casualties of Noncognate Coordination Chemistry
Copper (Cu) is an essential micronutrient for cells, but in excess it is cytotoxic. How Cu is cytotoxic is the subject of recent work by L. Zuily, N.
Charlotte I. Z. O’Hern+1 more
doaj +1 more source
Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli
New cryo-EM structures of the formate hydrogenlyase complex from the model bacterium E. coli clarify how electrons and protons move through the complex and are combined to make H2 gas.
Ralf Steinhilper+3 more
doaj +1 more source