Results 1 to 10 of about 22,661 (298)
Towards the spatial resolution of metalloprotein charge states by detailed modeling of XFEL crystallographic diffraction. [PDF]
Oxidation states of individual metal atoms within a metalloprotein can be assigned by examining X-ray absorption edges, which shift to higher energy for progressively more positive valence numbers.
Holton, James M +3 more
core +3 more sources
Metalloprotein Crystallography: More than a Structure [PDF]
Metal ions and metallocofactors play important roles in a broad range of biochemical reactions. Accordingly, it has been estimated that as much as 25–50% of the proteome uses transition metal ions to carry out a variety of essential functions.
Bowman, Sarah E. J. +2 more
core +2 more sources
Background Specific targeting ability and good cell penetration are two critical requirements of tumor-targeted delivery systems. In the present work, we developed a novel matrix metalloprotein-triggered, cell-penetrating, peptide-modified, star-shaped ...
Fangyuan Guo +10 more
doaj +2 more sources
The mussel byssus cuticle is a wear-resistant and extensible metalloprotein composite. Here, the authors probed the cuticle nanostructure and composition before, during and after fabrication revealing a crucial role of metal-binding proteins that self ...
Franziska Jehle +5 more
doaj +2 more sources
Machine Learning Approaches for Metalloproteins [PDF]
Metalloproteins are a family of proteins characterized by metal ion binding, whereby the presence of these ions confers key catalytic and ligand-binding properties.
Yue Yu, Ruobing Wang, Ruijie D. Teo
doaj +2 more sources
De novo metalloprotein design involves the construction of proteins guided by specific repeat patterns of polar and apolar residues, which, upon self-assembly, provides a suitable environment to bind metals and produce artificial metalloenzymes.
Pallavi Prasad +8 more
openalex +3 more sources
Changing paradigms for the micronutrient zinc, a known protein cofactor, as a signal relaying also cellular redox state [PDF]
The micronutrient zinc (Zn) is often poorly available but toxic when present in excess, so a tightly controlled Zn homoeostasis network operates in all organisms. This review summarizes our present understanding of plant Zn homoeostasis.
Ute Krämer
doaj +2 more sources
Improving Data Representation of Metalloproteins in the Protein Data Bank [PDF]
The Protein Data Bank (PDB) was established in 1971 as the first open-access digital data resource in biology, initially comprising just seven X- ray crystal structures of proteins.
Alison Biester +6 more
doaj +2 more sources
Online immunocapture ICP-MS for the determination of the metalloprotein ceruloplasmin in human serum
Objective The human copper-protein ceruloplasmin (Cp) is the major copper-containing protein in the human body. The accurate determination of Cp is mandatory for the reliable diagnosis of several diseases.
Bogdan Bernevic +3 more
doaj +2 more sources
Methanogenesis marker 16 metalloprotein is the primary coenzyme M synthase in Methanosarcina acetivorans. [PDF]
2-mercaptoethanesulfonate (Coenzyme M, CoM) is an organic sulfur-containing cofactor used for hydrocarbon metabolism in archaea and bacteria. In archaea, CoM serves as an alkyl group carrier for enzymes belonging to the alkyl-CoM reductase family ...
Grayson L Chadwick +3 more
doaj +2 more sources

