Results 1 to 10 of about 215,931 (289)

Matrix Effectors in the Pathogenesis of Keratinocyte-Derived Carcinomas

open access: yesFrontiers in Medicine, 2022
Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), referred to as keratinocyte carcinomas, are skin cancer with the highest incidence.
Rafaela-Maria Kavasi   +12 more
doaj   +1 more source

Influence of photodynamic therapy on the level of matrix metalloproteinases in squamous cell skin cancer

open access: yesBiomedical Photonics, 2022
The effect of photodynamic therapy (PDT) on the level of matrix metalloproteinases in squamous cell skin cancer (SCSC) was studied. The study involved 202 people, including 185 patients with SCSC, who were on outpatient and inpatient treatment in medical
V. V. Maslyakov   +3 more
doaj   +1 more source

Cell–Matrix Interactions in the Eye: From Cornea to Choroid

open access: yesCells, 2021
The extracellular matrix (ECM) plays a crucial role in all parts of the eye, from maintaining clarity and hydration of the cornea and vitreous to regulating angiogenesis, intraocular pressure maintenance, and vascular signaling.
Andrew E. Pouw   +8 more
doaj   +1 more source

Cosmetic Application of Cyanobacteria Extracts with a Sustainable Vision to Skincare: Role in the Antioxidant and Antiaging Process

open access: yesMarine Drugs, 2022
Nature-based and sustainably sourced cosmetics have been dominating the area of skincare products worldwide. Due to their antioxidant and antiaging properties, compounds from cyanobacteria, such as carotenoids and phycobiliproteins, may replace synthetic
Janaína Morone   +5 more
doaj   +1 more source

Skin Anti-Aging Potentials of Phytochemicals from Peperomia pellucida against Selected Metalloproteinase Targets: An In Silico Approach

open access: yesCosmetics, 2023
Skin aging and wrinkle formation are processes that are largely influenced by the overexpression of enzymes like tyrosinase, elastase, and collagenase. This study aimed to validate the skin anti-aging properties of phytochemicals from Peperomia pellucida
Babatunji Emmanuel Oyinloye   +9 more
doaj   +1 more source

Lymphangioleiomyomatosis: Searching for potential biomarkers

open access: yesFrontiers in Medicine, 2023
BackgroundVascular endothelial growth factor-D (VEGF-D) is the most commonly used biomarker for diagnosing lymphangioleiomyomatosis (LAM). However, lung biopsy is often necessary as well; therefore, defining new biomarkers for LAM is crucial.
Eva Revilla-López   +20 more
doaj   +1 more source

Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]

open access: yes, 2012
Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Djafarzadeh, Roghieh   +10 more
core   +11 more sources

Matrix Metalloproteinase 2 and 9 Enzymatic Activities are Selectively Increased in the Myocardium of Chronic Chagas Disease Cardiomyopathy Patients: Role of TIMPs

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Chronic Chagas disease (CCC) is an inflammatory dilated cardiomyopathy with a worse prognosis compared to other cardiomyopathies. We show the expression and activity of Matrix Metalloproteinases (MMP) and of their inhibitors TIMP (tissue inhibitor of ...
Monique Andrade Baron   +27 more
doaj   +1 more source

Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]

open access: yes, 2018
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila   +6 more
core   +2 more sources

Strategies to Target ADAM17 in Disease: From Its Discovery to the iRhom Revolution

open access: yesMolecules, 2021
For decades, disintegrin and metalloproteinase 17 (ADAM17) has been the object of deep investigation. Since its discovery as the tumor necrosis factor convertase, it has been considered a major drug target, especially in the context of inflammatory ...
Matteo Calligaris   +6 more
doaj   +1 more source

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