Results 41 to 50 of about 22,558 (250)
The ins and outs of metal homeostasis by the root nodule actinobacterium Frankia [PDF]
, 2014 Background: Frankia are actinobacteria that form a symbiotic nitrogen-fixing association with actinorhizal plants, and play a significant role in actinorhizal plant colonization of metal contaminated areas.
Furnholm, Teal R., Tisa, Louis S.
core +2 more sources
The Binding Mode of the Sonic Hedgehog Inhibitor Robotnikinin, a Combined Docking and QM/MM MD Study
Frontiers in Chemistry, 2017 Erroneous activation of the Hedgehog pathway has been linked to a great amount of cancerous diseases and therefore a large number of studies aiming at its inhibition have been carried out. One leverage point for novel therapeutic strategies targeting the
Manuel Hitzenberger +3 more
doaj +1 more source
Reactions of HNO with Metal Porphyrins: Underscoring the Biological Relevance of HNO [PDF]
, 2014 Azanone (1 HNO, nitroxyl) shows interesting yet poorly understood chemical and biological effects. HNO has some overlapping properties with nitric oxide (NO), sharing its biological reactivity toward heme proteins, thiols, and oxygen.
Bikiel, Damian Ezequiel +4 more
core +1 more source
Is the olfactory receptor a metalloprotein? [PDF]
Proceedings of the National Academy of Sciences, 2003 The sense of smell is arguably our most primal faculty and also the least understood. Even our own olfactorily impaired species is capable of detecting ≈10,000 distinct scents [Buck, L. & Axel, R. (1991)Cell65, 175–187]. To achieve that amazing diversity, mammals have ≈1,000 olfactory genes, which accounts for ≈3% of their entire genome [Mombaerts,
Zaida Luthey-Schulten +2 more
openaire +3 more sources
Mercury and selenium binding biomolecules in terrestrial mammals (Cervus elaphus and Sus scrofa) from a mercury exposed area [PDF]
, 2017 Acknowledgements The authors are grateful to Junta de Comunidades de Castilla-La Mancha (PCC-05-004-2, PAI06-0094, PCI-08-0096, PEII09-0032-5329) and the Ministerio de Economía y Competitividad (CTQ2013-48411-P) for financial support. M.J.
Fariñas, N. Rodríguez +5 more
core +1 more source
Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins
IUCrJ, 2019 An approach is demonstrated to obtain, in a sample- and time-efficient manner, multiple dose-resolved crystal structures from room-temperature protein microcrystals using identical fixed-target supports at both synchrotrons and X-ray free-electron lasers
Ali Ebrahim +14 more
doaj +1 more source
Frontiers in Chemistry, 2021 The development of accurate and efficient potential energy functions for the molecular dynamics simulation of metalloproteins has long been a great challenge for the theoretical chemistry community.
Mingyuan Xu +6 more
doaj +1 more source
Metallomics in environmental and health related research: Current status and perspectives [PDF]
, 2013 Metals and metalloids play distinct roles in human health, either beneficial or toxic, depending on their concentrations and species. There is an increasing interest in metals uptake, trafficking, function, and exertion in microorganisms to maintain and ...
G.B., J, He, B, Hu, L, Sun, H, Wang, Y
core +1 more source
Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Cofactors [PDF]
, 2019 Transition-metal catalysis is a powerful tool for the construction of chemical bonds. Here we show that a non-heme iron enzyme can catalyze olefin aziridination and nitrene C–H insertion, and that these activities can be improved by directed evolution ...
Arnold, Frances H. +3 more
core +1 more source
Advanced Materials, EarlyView.This review gives a summary on the representative bioinspired single‐atomic‐site catalysts (SACs) and their applications in heterogeneous electrocatalysis and photocatalysis. The fundamentals of bioinspired design strategies are systematically discussed in the context of the first shell coordination, the second/long‐range coordination, and the outer ...
Ying Wang +4 more
wiley +1 more source