Results 51 to 60 of about 9,301 (237)

Medication Safety in Intravenous Therapy: A Compatibility Study of Clonidine with Drugs Frequently Used in Intensive Care

open access: yesPharmaceutics, 2020
The intravenous pharmacotherapy of critically ill patients is extremely challenging due to the high number of drugs administered. We therefore evaluated the physicochemical compatibility of combinations of clonidine with drugs frequently used in an ...
Anna Katharina Koller   +2 more
doaj   +1 more source

Metamizole (dipyrone) – cytotoxic and antiproliferative effects on HeLa, HT-29 and MCF-7 cancer cell lines

open access: yesBiotechnology & Biotechnological Equipment, 2018
Cancer pain treatment is a big challenge for healthcare providers and patients as well. The wide range of non-steroidal anti-inflammatory drugs (NSAIDs) used as painkillers in cancer patients, requires in-depth characterization of their effect on the ...
Irina Nikolova   +6 more
doaj   +1 more source

Adverse drug reaction monitoring: support for pharmacovigilance at a tertiary care hospital in Northern Brazil [PDF]

open access: yes, 2013
BACKGROUND: Adverse drug reactions (ADRs) are recognised as a common cause of hospital admissions, and they constitute a significant economic burden for hospitals.
José Gerley Díaz Castro   +4 more
core   +1 more source

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]

open access: yes, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Flinspach, Armin Niklas   +5 more
core   +1 more source

Analgosedation in paediatric severe traumatic brain injury (TBI): practice, pitfalls and possibilities [PDF]

open access: yes, 2017
Analgosedation is a fundamental part of traumatic brain injury (TBI) treatment guidelines, encompassing both first and second tier supportive strategies.
de Lange, E.C.M. (E. C.M.)   +6 more
core   +3 more sources

Effects of metamizole, MAA, and paracetamol on proliferation, apoptosis, and necrosis in the pancreatic cancer cell lines PaTu 8988 t and Panc-1

open access: yesBMC Pharmacology and Toxicology, 2017
Background Adenocarcinoma of the pancreas is one of the most aggressive cancer diseases affecting the human body. Recent research has shown the importance of the perioperative phase in disease progression.
Manuela Malsy   +2 more
doaj   +1 more source

Adecuación de la seguridad del metamizol y agranulocitosis

open access: yesAtención Primaria, 2021
Resumen: Objetivo: Analizar si la nota informativa de la Agencia Española de Medicamentos y Productos Sanitarios (AEMPS), de 30 de octubre del 2018, sobre agranulocitosis y metamizol contiene la información precisa y necesaria para proteger a los ...
Cristina Garcia del Campo   +3 more
doaj   +1 more source

IgE-Mediated Reaction to Metamizole: Evaluation of a Patient with Severe Anaphylaxis

open access: yesEurasian Journal of Medicine, 2019
Metamizole, a non-steroidal anti-inflammatory drug with weak anti-inflammatory and spasmolytic effects, is used as an analgesic and antipyretic agent. Many adverse reactions to metamizole, such as early or late-onset systemic reactions and bone marrow ...
Sevket Arslan   +2 more
doaj   +1 more source

Ventral posteromedial nucleus of the thalamus as a neuroanatomical target for the anticephalalgic action of valproic acid and metamizole

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
Introduction. Valproic acid and metamizole are widely used in the treatment of primary headaches. However, despite the drugs’ proven clinical efficacy, the neurophysiological mechanisms underlying their therapeutic action are poorly understood.
A. Yu. Sokolov, O. A. Lyubashina
doaj   +1 more source

Metamizole (dipyrone) for multimodal analgesia in postoperative pain in adults

open access: yesPalliative Medicine in Practice
BACKGROUND: Metamizole (dipyrone) is a non-opioid analgesic used in perioperative analgesia in some countries. The drug has analgesic, antipyretic, and spasmolytic effects. The complex mechanism has not been fully explained yet. Presumably, the analgesic
Anna Dizner-Gołąb   +2 more
doaj   +1 more source

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