Results 51 to 60 of about 9,301 (237)
The intravenous pharmacotherapy of critically ill patients is extremely challenging due to the high number of drugs administered. We therefore evaluated the physicochemical compatibility of combinations of clonidine with drugs frequently used in an ...
Anna Katharina Koller +2 more
doaj +1 more source
Cancer pain treatment is a big challenge for healthcare providers and patients as well. The wide range of non-steroidal anti-inflammatory drugs (NSAIDs) used as painkillers in cancer patients, requires in-depth characterization of their effect on the ...
Irina Nikolova +6 more
doaj +1 more source
Adverse drug reaction monitoring: support for pharmacovigilance at a tertiary care hospital in Northern Brazil [PDF]
BACKGROUND: Adverse drug reactions (ADRs) are recognised as a common cause of hospital admissions, and they constitute a significant economic burden for hospitals.
José Gerley Díaz Castro +4 more
core +1 more source
Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Flinspach, Armin Niklas +5 more
core +1 more source
Analgosedation in paediatric severe traumatic brain injury (TBI): practice, pitfalls and possibilities [PDF]
Analgosedation is a fundamental part of traumatic brain injury (TBI) treatment guidelines, encompassing both first and second tier supportive strategies.
de Lange, E.C.M. (E. C.M.) +6 more
core +3 more sources
Background Adenocarcinoma of the pancreas is one of the most aggressive cancer diseases affecting the human body. Recent research has shown the importance of the perioperative phase in disease progression.
Manuela Malsy +2 more
doaj +1 more source
Adecuación de la seguridad del metamizol y agranulocitosis
Resumen: Objetivo: Analizar si la nota informativa de la Agencia Española de Medicamentos y Productos Sanitarios (AEMPS), de 30 de octubre del 2018, sobre agranulocitosis y metamizol contiene la información precisa y necesaria para proteger a los ...
Cristina Garcia del Campo +3 more
doaj +1 more source
IgE-Mediated Reaction to Metamizole: Evaluation of a Patient with Severe Anaphylaxis
Metamizole, a non-steroidal anti-inflammatory drug with weak anti-inflammatory and spasmolytic effects, is used as an analgesic and antipyretic agent. Many adverse reactions to metamizole, such as early or late-onset systemic reactions and bone marrow ...
Sevket Arslan +2 more
doaj +1 more source
Introduction. Valproic acid and metamizole are widely used in the treatment of primary headaches. However, despite the drugs’ proven clinical efficacy, the neurophysiological mechanisms underlying their therapeutic action are poorly understood.
A. Yu. Sokolov, O. A. Lyubashina
doaj +1 more source
Metamizole (dipyrone) for multimodal analgesia in postoperative pain in adults
BACKGROUND: Metamizole (dipyrone) is a non-opioid analgesic used in perioperative analgesia in some countries. The drug has analgesic, antipyretic, and spasmolytic effects. The complex mechanism has not been fully explained yet. Presumably, the analgesic
Anna Dizner-Gołąb +2 more
doaj +1 more source

