Results 21 to 30 of about 554,810 (355)

Comparisons of Metastatic Patterns, Survival Outcomes and Tumor Immune Microenvironment Between Young and Non-Young Breast Cancer Patients

Frontiers in Cell and Developmental Biology, 2022
Background: Metastases are the main cause of breast cancer-related deaths. Breast cancer has a more aggressive phenotype and less favorable prognosis in young females than in older females.
Hengwen Sun, Wei Huang, Fei Ji, Yi Pan, Lu Yang   +4 more
doaj   +1 more source

Cure in metastatic breast cancer [PDF]

memo - Magazine of European Medical Oncology, 2018
Oligometastatic disease characterizes a distinct subgroup of metastatic breast cancer patients that might benefit from different treatment strategies to achieve long-lasting remission and potentially cure. Those long-lasting remissions are reported after locoregional treatment of the primary tumor and all metastatic sites in several case series ...
Richard Greil, Theresa Westphal, Gabriel Rinnerthaler, Simon Peter Gampenrieder   +3 more
openaire   +3 more sources

The Metabolic Mechanisms of Breast Cancer Metastasis

Frontiers in Oncology, 2021
Breast cancer is one of the most common malignancy among women worldwide. Metastasis is mainly responsible for treatment failure and is the cause of most breast cancer deaths.
Lingling Wang, Lingling Wang, Shizhen Zhang, Xiaochen Wang   +3 more
doaj   +1 more source

Detection of Tumor Cell-Specific mRNA in the Peripheral Blood of Patients with Breast Cancer-Evaluation of Several Markers with Real-Time Reverse Transcription-PCR [PDF]

, 2013
It is widely known that cells from epithelial tumors, e. g., breast cancer, detach from their primary tissue and enter blood circulation. We show that the presence of circulating tumor cells (CTCs) in samples of patients with primary and metastatic ...
Alexandra Kölbl, Alix-Panabieres, Balbin, Bergqvist, Bernard, Bolke, Braun, Braun, Chang, Christian Schindlbeck, De Cremoux, Dontu, Dydensborg, Fabre-Lafay, Fleming, Frasor, Gervasoni, Giani, Guo, Hedenfalk, Inaba, Jiang, Julia Neugebauer, Kim, Klaus Friese, Konecny, Krawczyk, Kurec, Lafleur, Livak, Markou, Matthias Ilmer, Mendoza, Mitas, Moliterni, Nikseresht, Noack, Pan, Pantel, Ring, Selvamurugan, Simone Hofmann, Slamon, Smerage, Solomayer, Stefan Hutter, Tai, Udo Jeschke, Ulrich Andergassen, Vandesompele, Verena Engelstädter, Wang, Weissenstein, Wu, Wu, Zhang   +55 more
core   +3 more sources

Prognostic factors in metastatic breast cancer: a prospective single-centre cohort study in a Finnish University Hospital

BMJ Open, 2020
Objectives Although novel early breast cancer prognostic factors are being continuously discovered, only rare factors predicting survival in metastatic breast cancer have been validated.
Peeter Karihtala, Anniina Jääskeläinen, Nelli Roininen, Arja Jukkola   +3 more
doaj   +1 more source

Up-regulation of bone marrow stromal protein 2 (BST2) in breast cancer with bone metastasis

BMC Cancer, 2009
Background Bone metastases are frequent complications of breast cancer. Recent literature implicates multiple chemokines in the formation of bone metastases in breast cancer.
Zheng Xin, Li Zhen, Cao Jie, Cai Dongqing, Yao Yao, Li Wanglin, Yuan Ziqiang   +6 more
doaj   +1 more source

Development, implementation and evaluation of an online course on evidence-based healthcare for consumers

BMC Health Services Research, 2020
Background Evidence-based healthcare (EBHC) principles are essential knowledge for patient and consumer (“consumer”) engagement as research and research implementation stakeholders.
Genie Han, Musa Mayer, Joseph Canner, Kristina Lindsley, Reva Datar, Jimmy Le, Annette Bar-Cohen, Janice Bowie, Kay Dickersin   +8 more
doaj   +1 more source

Moonshots and metastatic disease: the need for a multi-faceted approach when studying atypical responses

npj Breast Cancer, 2017
Clinical research generally focuses on results involving a statistical mean with little attention in trial design to patients who respond considerably better or worse than average.
Kristine De La Torre, Elly Cohen, Anne Loeser, Marc Hurlbert, on behalf of the Metastatic Breast Cancer Alliance   +4 more
doaj   +1 more source

Targeted next-generation sequencing assays using triplet samples of normal breast tissue, primary breast cancer, and recurrent/metastatic lesions

BMC Cancer, 2020
Background Next-generation sequencing (NGS) has shown that recurrent/metastatic breast cancer lesions may have additional genetic changes compared with the primary tumor. These additional changes may be related to tumor progression and/or drug resistance.
Toshiaki Akahane, Naoki Kanomata, Oi Harada, Tetsumasa Yamashita, Junichi Kurebayashi, Akihide Tanimoto, Takuya Moriya   +6 more
doaj   +1 more source

In silico analysis of differentially expressed genesets in metastatic breast cancer identifies potential prognostic biomarkers

World Journal of Surgical Oncology, 2021
Background Identification of specific biological functions, pathways, and appropriate prognostic biomarkers is essential to accurately predict the clinical outcomes of and apply efficient treatment for breast cancer patients.
Jongchan Kim
doaj   +1 more source