Results 31 to 40 of about 554,810 (355)

Role of KCNMA1 gene in breast cancer invasion and metastasis to brain

BMC Cancer, 2009
Background The prognosis for patients with breast tumor metastases to brain is extremely poor. Identification of prognostic molecular markers of the metastatic process is critical for designing therapeutic modalities for reducing the occurrence of ...
Couraud Pierre-Olivier, Romero Ignacio A, Meister Edward A, Weksler Babette, Sankpal Umesh T, Khaitan Divya, Ningaraj Nagendra S   +6 more
doaj   +1 more source

Biopsy confirmation of metastatic sites in breast cancer patients:clinical impact and future perspectives [PDF]

, 2014
Determination of hormone receptor (estrogen receptor and progesterone receptor) and human epidermal growth factor receptor 2 status in the primary tumor is clinically relevant to define breast cancer subtypes, clinical outcome,and the choice of therapy ...
A Santinelli, AJ Montero, Alastair M Thompson, AM Thompson, Angela Esposito, Aron Goldhirsch, B Weigelt, BG Mobbs, C Liedtke, C Simmons, C Tapia, CA Gomez-Roca, Carmen Criscitiello, CH Lu, D Gancberg, DS Seah, E Amir, E Amir, E Brogi, EA Mittendorf, EA Perez, EA Perez, EE Lower, EE Lower, F Andre, F André, F Liebens, Fabrice André, Franco Orsi, G Aurilio, G Bogina, G Curigliano, G Viale, Giuseppe Curigliano, HJ Chang, Ida Minchella, J Carlsson, JM Wu, L Ding, L Pusztai, LD Hoefnagel, LM Bender, LS Lindstrom, LS Steelman, Luca Fumagalli, Lucia Gelao, M Scaltriti, Marzia Locatelli, Michele De Laurentiis, MJ Higgins, N Niikura, PJ Stephens, PK Idirisinghe, R Fisher, R Simon, RJ Broom, RJ Leary, S Gupta, S Vignot, SJ Aitken, SM Edgerton, SP Shah, ST Wong, T Forshew, U Wilking, V Guarneri, W Onstenk, Y Gong, Y Nagata, YM Lo   +69 more
core   +5 more sources

Serum atrial natriuretic peptide: a suspected biomarker of breast cancer

Contemporary Oncology, 2017
Aim of the study : To assess serum levels of ANP in breast cancer female patients and its relationship to metastasis and some clinical parameters among those patients.
Maha E. Houssen, Hayam F. Ghazy, Kamel Farag, Mona Abo Bakr El-Hussiny, Mohamed A. El Ghaffar, Sahar Alsayed Mohamed Alsayed, Omar Farouk   +6 more
doaj   +1 more source

Clinical relevance of soluble c-erbB-2 for patients with metastatic breast cancer predicting the response to second-line hormone or chemotherapy [PDF]

, 2002
Concentrations of soluble c-erbB-2 were determined in the sera of 64 patients with distant metastasis from advanced breast cancer receiving second-line hormone or chemotherapy in comparison to 35 breast cancer patients without detectable recurrent ...
Classen, S., Eiermann, W., Kopp, R., Possinger, K., Weidenhagen, R., Wilmanns, W.   +5 more
core   +1 more source

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis [PDF]

, 2011
Macrophages abundantly found in the tumor microenvironment enhance malignancy(1). At metastatic sites a distinct population of metastasis associated macrophages (MAMs) promote tumor cell extravasation, seeding and persistent growth(2).
AB Al-Mehdi, AD Borowsky, AJ Minn, AM Havens, B Brandt, B Qian, Bin-Zhi Qian, BS Nielsen, DR Getts, DR Rhodes, Elizabeth A. Kaiser, F Geissmann, F Geissmann, F Geissmann, FK Swirski, H Saji, HP Gerber, Hui Zhang, Jeffrey W. Pollard, JH Im, Jinghang Zhang, Jiufeng Li, JM Carton, Liam R. Campion, Linda A. Snyder, MD Abramoff, P Stern, P Tsui, RT Palframan, T Ueno, T Valkovic, Takanori Kitamura, Y Huang   +32 more
core   +2 more sources

Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics

Frontiers in Oncology, 2018
Metastatic breast cancer is currently incurable. It has recently emerged that different metabolic pathways support metastatic breast cancer. To further uncover metabolic pathways enabling breast cancer metastasis, we investigated metabolic differences in
Shao Thing Teoh, Martin P. Ogrodzinski, Martin P. Ogrodzinski, Christina Ross, Kent W. Hunter, Sophia Y. Lunt, Sophia Y. Lunt   +6 more
doaj   +1 more source

Human adipocytes stimulate invasion of breast cancer MCF-7 cells by secreting IGFBP-2. [PDF]

PLoS ONE, 2015
A better understanding of the effects of human adipocytes on breast cancer cells may lead to the development of new treatment strategies. We explored the effects of adipocytes on the migration and invasion of breast cancer cells both in vitro and in vivo.
Chen Wang, Chao Gao, Kui Meng, Haishi Qiao, Yong Wang   +4 more
doaj   +1 more source

Metastatic rectal cancer to the breast

Rare Tumors, 2009
Rectal cancer metastatic to the breast is an exceedingly rare event with around 15 cases reported in the literature. A metastatic breast deposit from the rectum signifies diffuse disseminated disease or a highly aggressive tumor such that surgical intervention other than palliation has a limited role.
Payal Kapur, Hsiao C. Li, Prapti A. Patel, Sergio Huerta   +3 more
openaire   +3 more sources

Sclerostin inhibition alleviates breast cancer-induced bone metastases and muscle weakness [PDF]

, 2019
Breast cancer bone metastases often cause a debilitating non-curable condition with osteolytic lesions, muscle weakness and a high mortality. Current treatment comprises chemotherapy, irradiation, surgery and anti-resorptive drugs that restrict but do ...
Brandt, Diana, Hesse, Eric, Pamperin, Jenny, Saito, Hiroaki, Schröder, Saskia, Taipaleenmäki, Hanna   +5 more
core   +1 more source

Network meta-analysis of eribulin versus other chemotherapies used as second- or later-line treatment in locally advanced or metastatic breast cancer

BMC Cancer, 2021
Background Eribulin mesylate (ERI; Halaven®) is a microtubule inhibitor approved in the United States for metastatic breast cancer patients with at least two prior chemotherapy regimens for metastatic breast cancer, and in the European Union in locally ...
Qi Zhao, Rachel Hughes, Binod Neupane, Kristin Mickle, Yun Su, Isabelle Chabot, Marissa Betts, Ananth Kadambi   +7 more
doaj   +1 more source