Results 1 to 10 of about 297,887 (387)

AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome [PDF]

open access: yes, 2016
Impairment in adenosine monophosphate-activated protein kinase (AMPK) activity and NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome activation are associated with several metabolic and inflammatory diseases.
Alcocer-Gómez, Elísabet   +5 more
core  

Effect of metformin on the level of aqueous humor inflammatory cytokines in patients with cataract

open access: yesScientific Reports
This study investigated the content of inflammatory cytokines in the aqueous humor (AH) of cataract patients with type 2 diabetes (T2DM) and explored the effect of metformin on the level of cytokines.
Jiaxi Li   +3 more
doaj   +1 more source

An update on pharmacotherapy for type 2 diabetes [PDF]

open access: yes, 2014
Glucose lowering drugs have been available for clinical use for over the past 60 years or so with the last 2 decades seeing a significant number of new agents being developed making treatment increasingly complex and also somewhat controversial.
Agius, Rachel
core  

Revealing the role of metformin in gastric intestinal metaplasia treatment

open access: yesFrontiers in Pharmacology
ObjectiveGastric intestinal metaplasia (IM) is a precancerous stage associated with gastric cancer. Despite the observed beneficial effects of metformin on IM, its molecular mechanism remains not fully elucidated.
Ruoyu Hu   +14 more
doaj   +1 more source

Pharmacologic effects of metformin in relation to its disposition in alloxan diabetic rats.

open access: bronze, 1983
Masawo Kakemi   +5 more
openalex   +2 more sources

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