Results 111 to 120 of about 205,038 (298)

Chinese expert consensus statement on metformin in clinical practice

open access: yesChinese Medical Journal, 2020
Expert Group of Metformin in Clinical Practice   +1 more
doaj   +1 more source

Green Synthesis of Silver Nanoparticles: A Review of Polymer and Antimicrobial Drug Combinations for Enhanced Antimicrobial Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan   +6 more
wiley   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

open access: yesHepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger   +7 more
wiley   +1 more source

Short-Term Metformin Therapy in Clomiphene Citrate Resistant PCOS Patients Improves Fertility Outcome by Regulating Follicular Fluid Redox Balance: A Case-Controlled Study

open access: yesDiagnostics
Objectives: To determine the effect of short-term metformin administration on follicular fluid (FF) total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI) and nuclear factor kappa B (NF-kB) in women with clomiphene ...
Mustafa Tas
doaj   +1 more source

Role of Mitochondria in the Mechanism(s) of Action of Metformin

open access: yesFrontiers in Endocrinology, 2019
Metformin is a drug from the biguanide family that is used for decades as the first-line therapeutic choice for the treatment of type 2 diabetes. Despite its worldwide democratization, owing to its clinical efficacy, high safety profile and cheap cost ...
G. Vial, D. Détaille, B. Guigas
semanticscholar   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Clinical effectiveness and treatment satisfaction between two triple‐therapy regimens in treating neuropathic pain: A real‐world data

open access: yesIbrain, EarlyView., 2023
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju   +7 more
wiley   +1 more source

Individual and collective transitions: Changes in family information networks over time in life with chronic illness

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract Chronic illness represents a transition for both patients and their family members although transitions and information behavior changes have largely been explored from an individual perspective. Illness‐related transitions may be undertaken individually or collectively, but little is known about how family information networks change in the ...
Lindsay K. Brown, Tiffany C. Veinot
wiley   +1 more source

The Effect of Metformin on Pregnancy Outcome Among Filipino Women with Polycystic Ovary Syndrome

open access: yesJournal of the ASEAN Federation of Endocrine Societies, 2014
Objective.To determine the effect of metformin on maternal and neonatal outcome among pregnant Filipino women with polycystic ovary syndrome (PCOS).   Methodology.This is a retrospective cohort study of PCOS women who were on metformin treatment prior
May Uyking-Naranjo   +3 more
doaj  

Prescribing competence: The pros and cons of different methods for assessment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman   +3 more
wiley   +1 more source

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