Results 161 to 170 of about 297,887 (387)

Piper auritum (Kunth) Fungal Endophytes: A Source of Metabolites to Inhibit the Formation of Advanced Glycation End Products

open access: yesChemistry &Biodiversity, EarlyView.
Endophytic fungi of P. auritum were evaluated for their ability to produce inhibitors of formation of advanced glycation end products (AGEs). Neopestalotiopsis sp. H2 and Diaporthe sp. H5 extracts were the most active. So, we performed their chemical profiling by untargeted and phenolics‐targeted metabolomic approaches to identify the potential ...
Lory Sthephany Rochín‐Hernández   +3 more
wiley   +1 more source

Chinese expert consensus statement on metformin in clinical practice

open access: yesChinese Medical Journal, 2020
Expert Group of Metformin in Clinical Practice   +1 more
doaj   +1 more source

The role of metformin in ovulation induction: Current status

open access: yesMiddle East Fertility Society Journal, 2011
To define the exact role of metformin in ovulation induction, it is crucial to distinguish three different indications: naïve PCOS, CC-resistant PCOS and ART.
Aboubakr Mohamed Elnashar
doaj   +1 more source

The cardiovascular safety of incretin-based therapies: a review of the evidence [PDF]

open access: yes, 2013
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in people with diabetes and therefore managing cardiovascular (CV) risk is a critical component of diabetes care. As incretin-based therapies are effective recent additions to the
Petrie, J.R.
core   +2 more sources

Antioxidants and Antidiabetic Potential of Polyphenolic Fractions and Crude Extracts of Rhus typhina Fruit, Punica granatum L. Peel, and Terminalia catappa L. Leaves: In Vitro and In Vivo Evaluation

open access: yesChemistry &Biodiversity, EarlyView.
This graphical abstract represents the extraction, characterization, and biological evaluation of bioactive compounds derived from specific plant sources. The top section illustrates Rhus coriaria (sumac) fruit, Punica granatum (pomegranate) peel and Terminalia catappa (Indian almond) leaves', which are known for their rich phytochemical composition ...
Mudassir Nazir   +8 more
wiley   +1 more source

Influence of phenformin and metformin on exercise induced lactataemia in patients with diabetes mellitus [PDF]

open access: bronze, 1978
P. Bj�rntorp   +6 more
openalex   +1 more source

Metformin: a metabolic modulator

open access: yesOncotarget, 2017
Recent findings have shed new light on the mechanisms of action through which biguanides exert their anti-aging and cytostatic effects in Caenorhabditis elegans and human cell lines. The drop in energy charge resulting from the metformin mediated inhibition of mitochondrial activity affects the function of the nuclear pore complex, blocks mTOR ...
Pietrocola, Federico, Kroemer, Guido
openaire   +4 more sources

Role of Mitochondria in the Mechanism(s) of Action of Metformin

open access: yesFrontiers in Endocrinology, 2019
Metformin is a drug from the biguanide family that is used for decades as the first-line therapeutic choice for the treatment of type 2 diabetes. Despite its worldwide democratization, owing to its clinical efficacy, high safety profile and cheap cost ...
G. Vial, D. Détaille, B. Guigas
semanticscholar   +1 more source

Harnessing Organometallic Au(III) Complexes as Precision Scaffolds for Next‐Generation Therapeutic and Imaging Agents

open access: yesChemBioChem, EarlyView.
Cyclometalated gold(III) complexes offer a versatile platform for selective biological interactions, including cysteine arylation, redox modulation, and enzyme inhibition. This review explores their roles in anticancer, antimicrobial, and protein modification strategies, highlighting their ability to disrupt metabolic pathways, modulate aquaporins, and
Sophie R. Thomas, Riccardo Bonsignore
wiley   +1 more source

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