Results 51 to 60 of about 297,887 (387)
Drugs in R & D, 2005 Metformin extended release [Glumetza, metformin hydrochloride, metformin gastric retention, metformin GR] is a proprietary once-a-day formulation of metformin hydrochloride under development with Depomed for the treatment of diabetes mellitus. In May 2002, Depomed licensed manufacturing and marketing rights for its proprietary formulation of metformin ...
openaire +4 more sources
NeuroSci, 2022 In our previous study, metformin was able to promote nerve regeneration after sciatic nerve crushing in rats under diabetic conditions. However, a crush injury also has a strong ability to spontaneously recover.
Junxiong Ma +4 more
doaj +1 more source
Metformin use in pregnancy: promises and uncertainties [PDF]
, 2017 Metformin has been prescribed in pregnancy for over 40 years; for much of this time, use has been limited both in numbers and geographically, and the evidence base has been confined to observational studies.
Lindsay, Robert S., Loeken, Mary R.
core +1 more source
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.
New England Journal of Medicine, 2006 BACKGROUND The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term glycemic control in type 2 diabetes is not known.
S. Kahn +10 more
semanticscholar +1 more source
Diabetes Care, 2021 OBJECTIVE To determine the longer-term effects of metformin treatment and behavioral weight loss on gut microbiota and short-chain fatty acids (SCFAs). RESEARCH DESIGN AND METHODS We conducted a 3-parallel-arm, randomized trial.
N. Mueller +7 more
semanticscholar +1 more source
Metformin promotes anticancer activity of NK cells in a p38 MAPK dependent manner
OncoImmunology, 2021 Metformin, a drug prescribed to treat type 2 diabetes, has been reported to possess antitumor activity via immunity activation. However, the influence of metformin on natural killer (NK) cells is not fully understood.
Wenjiao Xia +7 more
doaj +1 more source
Long-term metformin therapy and vitamin B12 deficiency: An association to bear in mind
World Journal of Diabetes, 2021 To date, metformin remains the first-line oral glucose-lowering drug used for the treatment of type 2 diabetes thanks to its well-established long-term safety and efficacy profile. Indeed, metformin is the most widely used oral insulin-sensitizing agent,
M. Infante +3 more
semanticscholar +1 more source
Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose [PDF]
, 2013 Background Diabetes is a risk factor for respiratory infection, and hyperglycaemia is associated with increased glucose in airway surface liquid and risk of Staphylococcus aureus infection.
Ali +47 more
core +1 more source
Protein & Cell, 2021 Chaperone-mediated autophagy (CMA) is a lysosome-dependent selective degradation pathway implicated in the pathogenesis of cancer and neurodegenerative diseases. However, the mechanisms that regulate CMA are not fully understood.
Xiaoyan Xu +14 more
semanticscholar +1 more source
Use of cystatin C to inform metformin eligibility among adult veterans with diabetes. [PDF]
, 2016 AimsRecommendations for metformin use are dependent on eGFR category: eGFR >45 ml/min/1.73 m2 - "first-line agent"; eGFR 30-44 - "use with caution"; eGFR<30 - "do not use".
Grunfeld, Carl +5 more
core +2 more sources