Rapid Methadone Metabolism in Opioid Use Disorder: A Case Report of Clinical Challenges and Individualized Treatment Approaches [PDF]
ReportsRapid methadone metabolism in patients with opioid use disorder could complicate methadone treatment. Toxicology screenings to monitor methadone levels may show negative for methadone, even with regular adherence to a regimen.
Farhana Nazmin +3 more
doaj +2 more sources
Harm Reduction Journal, 2023 Background During COVID-19, the Substance Abuse and Mental Health Services Administration (SAMHSA) allowed Methadone Maintenance Treatment (MMT) programs to relax in-person MMT requirements to reduce COVID-19 exposure.
Sarah Brothers +6 more
doaj +1 more source
Canadian Family Physician, 2021 As a pharmacist who has been dispensing methadone for more than 20 years to patients in and out of Ontario provincial jails, I read the article by Raski et al in the November issue[1][1] with interest (and gratitude to one of the doctors on our team, who thoughtfully clipped this article out of ...
openaire +2 more sources
Interest without uptake: A mixed-methods analysis of methadone utilization in Kyrgyz prisons.
PLoS ONE, 2022 HIV incidence continues to increase in Eastern Europe and Central Asia (EECA), in large part due to non-sterile injection drug use, especially within prisons. Therefore, medication-assisted therapy with opioid agonists is an evidence-based HIV-prevention
Amanda R Liberman +8 more
doaj +1 more source
Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients. [PDF]
PLoS Genetics, 2016 Methadone maintenance treatment (MMT) is commonly used for controlling opioid dependence, preventing withdrawal symptoms, and improving the quality of life of heroin-dependent patients.
Hsin-Chou Yang +7 more
doaj +1 more source
The nature of methadone diversion in England: a Merseyside case study
Harm Reduction Journal, 2012 Background Methadone maintenance treatment (MMT) is a key element in treatment for opiate addiction; however concerns about the diversion of methadone remain. More current empirical data on methadone diversion are required. This research investigated the
Duffy Paul, Baldwin Helen
doaj +1 more source
Psychopathology and urine toxicology in methadone patients
Mental Illness, 2015 Several studies reported high rates of psychiatric commorbidity among methadone patients. We examined the relationships of measures of psychopathology to outcomes of screening urine tests for cocaine, opiates, and benzodiazepines in a sample of 56 ...
Gamal Sadek, Zack Cernovsky, Simon Chiu
doaj +1 more source
Toward precision prescribing for methadone: Determinants of methadone deposition.
PLoS ONE, 2020 BackgroundDespite the World Health Organization listing methadone as an essential medication, effective dose selection is challenging, especially in racial and ethnic minority populations.
Andrew H Talal +9 more
doaj +1 more source
Sedative and antinociceptive effects of different combinations of detomidine and methadone in standing horses [PDF]
, 2017 Objective To evaluate intravenous (IV) detomidine with methadone in horses to identify a combination which provides sedation and antinociception without adverse effects. Study design Randomized, placebo-controlled, blinded, crossover.
Crosignani, N +6 more
core +2 more sources
Scientific Reports, 2021 The search continues for improved therapy for acute lymphoblastic leukemia (aLL), the most common malignancy in children. Recently, d,l-methadone was put forth as sensitizer for aLL chemotherapy.
JungKwon Lee +3 more
doaj +1 more source