Results 101 to 110 of about 104,643 (306)

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Impact of ABCB1 and CYP2B6 genetic polymorphisms on methadone metabolism, dose and treatment response in patients with opioid addiction: a systematic review and meta-analysis.

PLoS ONE, 2014
BackgroundGenetic variability may influence methadone metabolism, dose requirements, and risk of relapse.ObjectivesTo determine whether the CYP2B6*6 or ABCB1 (rs1045642) polymorphisms are associated with variation in methadone response (plasma ...
Brittany B Dennis, Monica Bawor, Lehana Thabane, Zahra Sohani, Zainab Samaan   +4 more
doaj   +1 more source

Neonatal outcomes after fetal exposure to methadone and buprenorphine: national registry studies from the Czech Republic and Norway [PDF]

, 2018
Blanka Nechanská, Viktor Mravčík, Svetlana Skurtveit, Ingunn Olea Lund, Roman Gabrhelík, Anders Engeland, Marte Handal   +6 more
openalex   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Accidental Methadone Toxicity in a 3-Year-Old Leading to Severe Cerebellitis and Death: A Case Report

Case Reports in Pediatrics
Methadone is a synthetic opioid used to treat pain and opioid dependence. Despite its benefits, accidental ingestion of methadone in pediatric patients can lead to significant morbidity and mortality.
Jessie Pappin, Greg Hansen, Tanya Holt
doaj   +1 more source

Looking at a Blind Spot: Using a Longitudinal Population Cohort Study to Examine Inequalities in Child Social Worker Contact Among Mothers Experiencing Domestic Abuse in Scotland

Child &Family Social Work, EarlyView.
ABSTRACT Research on inequalities in children's services in the UK highlights a lack of systematic data on parental demographics, obstructing analysis of structural factors influencing children's outcomes. Using Growing Up in Scotland, a nationally representative longitudinal child cohort study of children born in 2004–2005, we investigate social ...
Valeria Skafida, Eve Mullins, John Devaney   +2 more
wiley   +1 more source

A Case Report of Neuroleptic Malignant Syndrome during Methadone Therapy

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022
Background and Objective: Methadone is an opioid agonist used for the treatment of addiction to opioid drugs. Toxic leukoencephalopathy can cause serious problem and even be life-threatening.
MJ Nasr, AH Zohrevand, D Hosseini Talari, A Alizadeh Khatir   +3 more
doaj  

An intervention to improve provider-patient interaction at methadone maintenance treatment in China. [PDF]

, 2019
BackgroundThis study evaluated an intervention aiming to improve methadone maintenance therapy (MMT) service providers' interaction with their patients in China.MethodsSixty-eight MMT clinics were randomized to either an intervention or a control ...
Cao, Wei, Feng, Nan, Li, Li, Liang, Li-Jung, Lin, Chunqing, Wu, Zunyou   +5 more
core  

The OPRD1 rs678849 variant influences outcome of disulfiram treatment for cocaine dependency in methadone-maintained patients

, 2021
P. Thomas, Fuhr Nielsen Emil, Catherine J. Spellicy, Mark J. Harding, An Ye, Michelle A. Patriquin, Sara Hamon, Thomas R. Kosten, David A. Nielsen   +8 more
openalex   +2 more sources

Needle tenoscopy of the digital flexor tendon sheath in four horses

Equine Veterinary Education, EarlyView.
Summary Background Tenoscopy, performed under general anaesthesia (GA), remains the gold standard diagnostic modality for assessment of the digital flexor tendon sheath (DFTS). A cadaver study described needle tenoscopy of the DFTS in a standing horse model, but the procedure has not been reported in clinical cases.
L. J. Breen, C. M. Baldwin, J. R. Vos, A. M. Gillen, J. D. Stack   +4 more
wiley   +1 more source