Results 131 to 140 of about 118,303 (321)

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Cardiovascular Complications Following Acute Methadone Poisoning in Patients with and Without a History of Long-term Methadone Use

Journal of Research in Pharmacy Practice
Objective: Given the prevalence of methadone poisoning, this study was conducted to compare the cardiovascular complications following acute methadone poisoning in patients with and without a history of long-term methadone use.
Gholamali Dorooshi, Mahbod Shirmohammadi, Farzad Gheshlaghi, Arman Otroshi, Shafeajafar Zoofaghari, Nastaran Eizadi-Mood   +5 more
doaj   +1 more source

Looking at a Blind Spot: Using a Longitudinal Population Cohort Study to Examine Inequalities in Child Social Worker Contact Among Mothers Experiencing Domestic Abuse in Scotland

Child &Family Social Work, EarlyView.
ABSTRACT Research on inequalities in children's services in the UK highlights a lack of systematic data on parental demographics, obstructing analysis of structural factors influencing children's outcomes. Using Growing Up in Scotland, a nationally representative longitudinal child cohort study of children born in 2004–2005, we investigate social ...
Valeria Skafida, Eve Mullins, John Devaney   +2 more
wiley   +1 more source

Patient and Prescriber characteristics associated with return to daily-dispense methadone: A multilevel cohort study.

PLOS Mental Health
Early in the SARS-Cov-2 pandemic, modified clinical guidance recommended the provision of take-home methadone doses for those previously ineligible to facilitate social distancing.
Ria Garg, Shaleesa Ledlie, Daniel McCormack, Nikki Bozinoff, Jennifer Wyman, Beth Sproule, Pamela Leece, Mina Tadrous, Ashley Smoke, Charlotte Munro, Tara Gomes   +10 more
doaj   +1 more source

Needle tenoscopy of the digital flexor tendon sheath in four horses

Equine Veterinary Education, EarlyView.
Summary Background Tenoscopy, performed under general anaesthesia (GA), remains the gold standard diagnostic modality for assessment of the digital flexor tendon sheath (DFTS). A cadaver study described needle tenoscopy of the DFTS in a standing horse model, but the procedure has not been reported in clinical cases.
L. J. Breen, C. M. Baldwin, J. R. Vos, A. M. Gillen, J. D. Stack   +4 more
wiley   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Possible association of short‐term complications and antimicrobial use in standing equine cheek tooth extractions 2018–2022

Equine Veterinary Journal, EarlyView.
Abstract Background Despite growing concerns about antimicrobial resistance, prophylactic antimicrobials continue to be routinely administered in many procedures, including dental extractions. Further evidence‐based research is needed on whether their use influences post‐operative complication rates.
Marlies Schnierer, Omid Nekouei, Lisa Christina Huber, Matthias Jehle, Nora Biermann   +4 more
wiley   +1 more source

The Five Factor Model of personality and evaluation of drug consumption risk

, 2017
The problem of evaluating an individual's risk of drug consumption and misuse is highly important. An online survey methodology was employed to collect data including Big Five personality traits (NEO-FFI-R), impulsivity (BIS-11), sensation seeking (ImpSS)
A. Terracciano, A.N. Gorban, A.N. Gorban, A.N. Kopstein, C.A. Ventura, D.N. Gujarati, D.W. Hosmer Jr, D.W. Scott, E.M. Mirkes, E.M. Mirkes, F. Bulut, G. Biau, G.P. McCabe, H.F. Kaiser, I.D. Dinov, J. Hoare, J.R. Quinlan, K. Pearson, K.L. Clarkson, L. Guttman, M. Linting, M. Zuckerman, M.J. Cleveland, M.S. Stanford, P.T. Costa, Q. Li, R. Beaglehole, R.A. Fisher, R.R. McCrae, S. Arlot, S. Russell, S. Valeroa, S.Y. Lee, T. Bogg, T. Hastie, T. Hastie, V. Egan, Y. Benjamini, Y. Koren   +38 more
core   +1 more source

Cardiac Assessment of Individuals with Opioid Use Disorder under Methadone Treatment

Journal of Research in Pharmacy Practice
Objective: Methadone treatment is effective for managing opioid use disorder (OUD) but raises concerns about its impact on cardiac function. This study aimed to assess the prevalence of cardiac dysfunction among individuals under methadone treatment ...
Hoda Barkhordari, Mohammad Masoumi, Mansour Moazenzadeh, Hamidreza Esmaili, Hamidreza Rashidinejad   +4 more
doaj   +1 more source

Reduction of opioid and barbiturate use following initiation of rimegepant for migraine in the United States

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The primary objective of this study was to evaluate opioid and barbiturate utilization before and after the first prescription of the calcitonin gene–related peptide receptor antagonist rimegepant in individuals with migraine. Background Although not recommended in migraine treatment guidelines, opioids and barbiturates are often ...
Noah Rosen, Aaron Jenkins, Karin Hygge Blakeman, Feng Dai, Lucy Abraham, Chelsea Leroue, Josh Brown   +6 more
wiley   +1 more source