The relationship between methadone dosage and plasma level changes with aging in methadone maintenance treatment (MMT) patients [PDF]
Substance Abuse Treatment, Prevention, and PolicyBackground As aging is associated with physiological changes, patients in methadone maintenance treatment (MMT) may require an adequate methadone dose adjustment.
Anat Sason +3 more
doaj +2 more sources
Rapid Methadone Metabolism in Opioid Use Disorder: A Case Report of Clinical Challenges and Individualized Treatment Approaches [PDF]
ReportsRapid methadone metabolism in patients with opioid use disorder could complicate methadone treatment. Toxicology screenings to monitor methadone levels may show negative for methadone, even with regular adherence to a regimen.
Farhana Nazmin +3 more
doaj +2 more sources
Perceived barriers to methadone maintenance treatment among Iranian opioid users
International Journal for Equity in Health, 2018 BackgroundOpioid use is a severe problem in Iran. Despite methadone maintenance treatment (MMT) programs being one of the most important treatment strategies for reducing individual and public harms associated with opioid use, a large proportion of ...
M. Khazaee-Pool +5 more
semanticscholar +3 more sources
Trends in Opioid Agonist Treatment for Opioid Dependence During Pregnancy: A Population-Based Study in New South Wales 2005-2021. [PDF]
Drug Alcohol RevABSTRACT Introduction The objective of this study was to examine trends in opioid agonist treatment (OAT) during pregnancy for opioid dependence, by OAT type (methadone, buprenorphine) and during‐pregnancy OAT type change. Methods Data linkage study. The cohort included pregnancies resulting in childbirth among people who received OAT within 4 years ...
Tran DT +8 more
europepmc +2 more sources
Harm Reduction Journal, 2023 Background During COVID-19, the Substance Abuse and Mental Health Services Administration (SAMHSA) allowed Methadone Maintenance Treatment (MMT) programs to relax in-person MMT requirements to reduce COVID-19 exposure.
Sarah Brothers +6 more
doaj +1 more source
Interest without uptake: A mixed-methods analysis of methadone utilization in Kyrgyz prisons.
PLoS ONE, 2022 HIV incidence continues to increase in Eastern Europe and Central Asia (EECA), in large part due to non-sterile injection drug use, especially within prisons. Therefore, medication-assisted therapy with opioid agonists is an evidence-based HIV-prevention
Amanda R Liberman +8 more
doaj +1 more source
Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients. [PDF]
PLoS Genetics, 2016 Methadone maintenance treatment (MMT) is commonly used for controlling opioid dependence, preventing withdrawal symptoms, and improving the quality of life of heroin-dependent patients.
Hsin-Chou Yang +7 more
doaj +1 more source
The nature of methadone diversion in England: a Merseyside case study
Harm Reduction Journal, 2012 Background Methadone maintenance treatment (MMT) is a key element in treatment for opiate addiction; however concerns about the diversion of methadone remain. More current empirical data on methadone diversion are required. This research investigated the
Duffy Paul, Baldwin Helen
doaj +1 more source
Toward precision prescribing for methadone: Determinants of methadone deposition.
PLoS ONE, 2020 BackgroundDespite the World Health Organization listing methadone as an essential medication, effective dose selection is challenging, especially in racial and ethnic minority populations.
Andrew H Talal +9 more
doaj +1 more source
Harm Reduction Journal, 2017 Background Methadone maintenance therapy (MMT) is a mainstay for treating opioid use disorder and preventing and managing HIV among people who inject drugs (PWID).
Kanna Hayashi +6 more
doaj +1 more source