Results 11 to 20 of about 130,679 (320)

Intravenous methadone for pain management in cardiac surgery: a randomised controlled trial with plasma concentration analysis. [PDF]

Anaesthesia
Summary Introduction Postoperative pain after cardiac surgery remains significant despite the administration of opioids. Methadone may improve pain control and decrease the need for postoperative opioids. Randomised controlled trials, however, are limited and the effects of cardiopulmonary bypass on methadone pharmacokinetics are unclear.
Wong HMK, Lai VKW, Chiu SLC, Wong WT, Wo SK, Zuo JZ, Liu X, Wong RHL, Ho KM.   +8 more
europepmc   +4 more sources

Opioid treatment program and community pharmacy collaboration for methadone maintenance treatment: Results from a feasibility clinical trial.

Addiction, 2021
BACKGROUND AND AIMS Pharmacy administration and dispensing of methadone for methadone maintenance treatment (MMT) can expand treatment access for opioid use disorder (OUD).
Li-Tzy Wu, W. John, Eric D. Morse, Steve Adkins, J. Pippin, R. Brooner, R. Schwartz   +6 more
semanticscholar   +1 more source

Research priorities for expanding access to methadone treatment for opioid use disorder in the United States: A National Institute on Drug Abuse Clinical Trials Network Task Force report

Substance Abuse, 2021
In the US, methadone treatment can only be provided to patients with opioid use disorder (OUD) through federal and state-regulated opioid treatment programs (OTPs).
P. J. Joudrey, G. Bart, R. Brooner, Lawrence S. Brown, Julia Dickson-Gomez, A. Gordon, S. Kawasaki, J. Liebschutz, E. Nunes, D. McCarty, R. Schwartz, José Szapocnik, M. Trivedi, J. Tsui, A. Williams, Li-Tzy Wu, D. Fiellin   +16 more
semanticscholar   +1 more source

Interest without uptake: A mixed-methods analysis of methadone utilization in Kyrgyz prisons.

PLoS ONE, 2022
HIV incidence continues to increase in Eastern Europe and Central Asia (EECA), in large part due to non-sterile injection drug use, especially within prisons. Therefore, medication-assisted therapy with opioid agonists is an evidence-based HIV-prevention
Amanda R Liberman, Daniel J Bromberg, Taylor Litz, Ainura Kurmanalieva, Samy Galvez, Julia Rozanova, Lyu Azbel, Jaimie P Meyer, Frederick L Altice   +8 more
doaj   +1 more source

Methadone for Opioid Use Disorder-Decades of Effectiveness but Still Miles Away in the US.

JAMA psychiatry, 2020
In 1974, President Nixon signed the Narcotic Addiction Treatment Act, which gave statutory authority to the regulations governing the provision of methadone for the treatment of opioid use disorder (OUD) in the US.
P. J. Joudrey, E. J. Edelman, E. Wang
semanticscholar   +1 more source

The nature of methadone diversion in England: a Merseyside case study

Harm Reduction Journal, 2012
Background Methadone maintenance treatment (MMT) is a key element in treatment for opiate addiction; however concerns about the diversion of methadone remain. More current empirical data on methadone diversion are required. This research investigated the
Duffy Paul, Baldwin Helen
doaj   +1 more source

Psychopathology and urine toxicology in methadone patients

Mental Illness, 2015
Several studies reported high rates of psychiatric commorbidity among methadone patients. We examined the relationships of measures of psychopathology to outcomes of screening urine tests for cocaine, opiates, and benzodiazepines in a sample of 56 ...
Gamal Sadek, Zack Cernovsky, Simon Chiu
doaj   +1 more source

Toward precision prescribing for methadone: Determinants of methadone deposition.

PLoS ONE, 2020
BackgroundDespite the World Health Organization listing methadone as an essential medication, effective dose selection is challenging, especially in racial and ethnic minority populations.
Andrew H Talal, Yuxin Ding, Charles S Venuto, Lindsay M Chakan, Anthony McLeod, Arpan Dharia, Gene D Morse, Lawrence S Brown, Marianthi Markatou, Evan D Kharasch   +9 more
doaj   +1 more source

Simultaneous determination of methadone and morphine at a modified electrode with 3D β-MnO2 nanoflowers: application for pharmaceutical sample analysis

RSC Advances, 2020
The present research synthesized manganese dioxide nano-flowers (β-MnO2-NF) via a simplified technique for electro-catalytic utilization. Moreover, morphological characteristics and X-ray analyses showed Mn in the oxide form with β-type crystallographic ...
S. Akbari, S. Jahani, M. Foroughi, Hadi Hassani Nadiki   +3 more
semanticscholar   +1 more source

Sedative and antinociceptive effects of different combinations of detomidine and methadone in standing horses [PDF]

, 2017
Objective To evaluate intravenous (IV) detomidine with methadone in horses to identify a combination which provides sedation and antinociception without adverse effects. Study design Randomized, placebo-controlled, blinded, crossover.
Crosignani, N, Gozalo-Marcilla, M, Luna, S P L, Pelligand, L, Possebon, F S, Puoli Filho, J N P, Taylor, P M   +6 more
core   +2 more sources