Results 31 to 40 of about 102,331 (342)

Methadone ameliorates multiple-low-dose streptozotocin-induced type 1 diabetes in mice [PDF]

Type 1 diabetes is an autoimmune disease characterized by inflammation of pancreatic islets and destruction of β cells by the immune system. Opioids have been shown to modulate a number of immune functions, including T helper 1 (Th1) and T helper 2 ...
امیرشاهرخی, کیوان, حاجتی, جمشيد, دهپور, احمدرضا, ستوده, مسعود, قاضی خوانساری, محمود   +4 more
core   +1 more source

Awareness of the need for safe storage of Methadone at home is not improved by the use of protocols on recording information giving

Harm Reduction Journal, 2008
Background Methadone is a synthetic, narcotic analgesic used in the treatment of drug misuse. Tragedies involving children being poisoned by the accidental ingestion of methadone are no longer a rare occurrence. Following an audit of the effectiveness of
Crome Ilana B, Watts Derrett J, McAuley Rosanna J, Mullin Annemarie, Bloor Roger N   +4 more
doaj   +1 more source

Methadone’s Moment [PDF]

JAMA
This work discusses unfettering methadone from outdated regulations to empower patients to access treatment and advocate for methadone's expansion in their local communities by working with pharmacies and local health systems.
Incze, Michael A, Simon, Caty, Suen, Leslie W   +2 more
openaire   +3 more sources

Magnesium Salt, a Simple Strategy to Improve Methadone Analgesia in Chronic Pain: An Isobolographic Preclinical Study in Neuropathic Mice

Frontiers in Pharmacology, 2020
Analgesic efficacy of methadone in cancer and chronic non-cancer pains is greater than that of other opioids, probably because of its unique pharmacokinetics properties and also because it targets glutamatergic receptors in addition to µ-opioid receptors.
Valeria González, Teresa Pelissier, Victoria Cazanga, Alejandro Hernández, Luis Constandil, Luis Constandil   +5 more
doaj   +1 more source

Treating Homeless Opioid Dependent Patients with Buprenorphine in an Office-Based Setting [PDF]

, 2007
CONTEXT Although office-based opioid treatment with buprenorphine (OBOT-B) has been successfully implemented in primary care settings in the US, its use has not been reported in homeless patients.
Alford, Daniel P., Cheng, Debbie M., Hohl, Carole A., LaBelle, Colleen T., O'Connell, James J., Richardson, Jessica M., Samet, Jeffrey H.   +6 more
core   +3 more sources

Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]

, 2009
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S., Robson , Noorzurani, Vicknasingam, B.   +2 more
core  

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Analysis of Methadone-Related Poisoning Cases

Fayixue Zazhi
ObjectiveTo analyze the characteristics of methadone-related poisoning cases and provide a reference for forensic identification.MethodsA total of 71 cases of methadone-related poisoning reported from 1998 to 2023 in China and 26 cases of methadone ...
LI Ze-qi, XING Lei, ZHANG Hui-ge, HE Li-rou, ZHANG Jia-yi, WANG Jia-qi, LIU Shi-hao, YANG Wei-hong   +7 more
doaj   +1 more source

An evaluation of a methadone treatment programme : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Psychology at Massey University [PDF]

, 1987
The evaluation of a methadone treatment programme was the main focus of this study. A posttest-only design, with a nonequivalent comparison group was used to evaluate both summative and formative aspects of the programme.
Clark, Jahna
core  

Ethanol reversal of tolerance to the respiratory depressant effects of morphine [PDF]

, 2015
Opioids are the most common drugs associated with unintentional drug overdose. Death results from respiratory depression. Prolonged use of opioids results in the development of tolerance but the degree of tolerance is thought to vary between different ...
A Fugelstad, A Fugelstad, Abi Lyndon, AJ Ruttenber, Anne Lingford-Hughes, AR Lingford-Hughes, B Levine, BM Mathers, CA Paronis, Chris Bailey, CK Kuo, CN Lessov, CP Bailey, CP Bailey, CP Bailey, E Kelly, E Valjent, Eamonn Kelly, EB Rex, EJ Waite, F Chen, FL Smith, FL Smith, Graeme Henderson, GS Ling, H Sakakibara, HW Matthes, HY Lin, I Rodriguez-Martin, J Llorente, J McPherson, J Reneau, JM White, Joanne Roberts, John MacLachlan, JT Williams, JW Lewis, KL McGilliard, L He, LC Hull, LC Saland, LJ Sim-Selley, LM Bohn, LQ Hong-Brown, M Aliczki, M Hickman, M Hickman, M Inoue, M Pierce, Matthew Hickman, N Quillinan, NG Shah, R Cornish, R Romberg, Rob Hill, S Darke, S Darke, S Kishioka, Sarah Withey, SJ Slater, SV Dighe, TC Green, Yvonne Kershaw   +62 more
core   +3 more sources