Results 41 to 50 of about 126,285 (384)
Anesthesia and Analgesia, 2019 BACKGROUND Methadone is a potent opioid exerting an analgesic effect through N-methyl-D-aspartate receptor antagonism and the inhibition of serotonin and noradrenaline reuptake. It has also been used in several procedures to reduce postoperative pain and
F. Machado +3 more
semanticscholar +1 more source
Effect of Swimming Training in Withdrawal Period on Thyroid Hormones of Addicted Rats [PDF]
Report of Health Care, 2016 Introduction: Today, drug use is increasing in the world. Physiological changes in the body are one of the most important consequences of drug use; one of the most important of these changes is the hormonal changes in the body.
Abdossaleh Zar +4 more
doaj
World Journal of Colorectal Surgery, 2023 Background: Postoperative pain control is an important aspect in the recovery of patients. Recent literature suggests that the extended half-life of methadone may reduce overall opioid utilization in postoperative patients.
Nathan S Kau
doaj +1 more source
Harm Reduction Journal, 2008 Background Methadone is a synthetic, narcotic analgesic used in the treatment of drug misuse. Tragedies involving children being poisoned by the accidental ingestion of methadone are no longer a rare occurrence. Following an audit of the effectiveness of
Crome Ilana B +4 more
doaj +1 more source
Methadone ameliorates multiple-low-dose streptozotocin-induced type 1 diabetes in mice [PDF]
Type 1 diabetes is an autoimmune disease characterized by inflammation of pancreatic islets and destruction of β cells by the immune system. Opioids have been shown to modulate a number of immune functions, including T helper 1 (Th1) and T helper 2 ...
امیرشاهرخی, کیوان +4 more
core +1 more source
Addiction, 2018 Aims To estimate whether opioid substitution treatment (OST) with buprenorphine or methadone is associated with a greater reduction in the risk of all‐cause mortality (ACM) and opioid drug‐related poisoning (DRP) mortality.
M. Hickman +9 more
semanticscholar +1 more source
Harm reduction among injecting drug users - evidence of effectiveness [PDF]
, 2010 This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Goldberg, David +5 more
core +1 more source
JAMAThis work discusses unfettering methadone from outdated regulations to empower patients to access treatment and advocate for methadone's expansion in their local communities by working with pharmacies and local health systems.
Incze, Michael A +2 more
openaire +3 more sources
Anesthesia and Analgesia, 2019 BACKGROUND: Approximately 50 million US patients undergo ambulatory surgery annually. Postoperative opioid overprescribing is problematic, yet many patients report inadequate pain relief.
H. Komen +4 more
semanticscholar +1 more source
Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]
, 2009 Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S. +2 more
core