Results 41 to 50 of about 118,303 (321)

Methadone ameliorates multiple-low-dose streptozotocin-induced type 1 diabetes in mice [PDF]

Type 1 diabetes is an autoimmune disease characterized by inflammation of pancreatic islets and destruction of β cells by the immune system. Opioids have been shown to modulate a number of immune functions, including T helper 1 (Th1) and T helper 2 ...
امیرشاهرخی, کیوان, حاجتی, جمشيد, دهپور, احمدرضا, ستوده, مسعود, قاضی خوانساری, محمود   +4 more
core   +1 more source

Methadone treatment and patient-directed hospital discharges among patients with opioid use disorder: Observations from general medicine services at an urban, safety-net hospital

Drug and Alcohol Dependence Reports, 2022
Introduction: People with opioid use disorder (OUD) have high rates of discharge against medical advice from the hospital. Interventions for addressing these patient-directed discharges (PDDs) are lacking.
Hannah R. Tierney, Christopher L. Rowe, Diana A. Coffa, Shashi Sarnaik, Phillip O. Coffin, Hannah R. Snyder   +5 more
doaj   +1 more source

Intraoperative Methadone in Same-Day Ambulatory Surgery: A Randomized, Double-Blinded, Dose-Finding Pilot Study

Anesthesia and Analgesia, 2019
BACKGROUND: Approximately 50 million US patients undergo ambulatory surgery annually. Postoperative opioid overprescribing is problematic, yet many patients report inadequate pain relief.
H. Komen, L. Michael Brunt, E. Deych, J. Blood, Evan D. Kharasch   +4 more
semanticscholar   +1 more source

Awareness of the need for safe storage of Methadone at home is not improved by the use of protocols on recording information giving

Harm Reduction Journal, 2008
Background Methadone is a synthetic, narcotic analgesic used in the treatment of drug misuse. Tragedies involving children being poisoned by the accidental ingestion of methadone are no longer a rare occurrence. Following an audit of the effectiveness of
Crome Ilana B, Watts Derrett J, McAuley Rosanna J, Mullin Annemarie, Bloor Roger N   +4 more
doaj   +1 more source

Intraoperative Methadone Use in Patients Undergoing Minimally Invasive Colorectal Surgical Procedures

World Journal of Colorectal Surgery, 2023
Background: Postoperative pain control is an important aspect in the recovery of patients. Recent literature suggests that the extended half-life of methadone may reduce overall opioid utilization in postoperative patients.
Nathan S Kau
doaj   +1 more source

The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom

Addiction, 2018
Aims To estimate whether opioid substitution treatment (OST) with buprenorphine or methadone is associated with a greater reduction in the risk of all‐cause mortality (ACM) and opioid drug‐related poisoning (DRP) mortality.
M. Hickman, C. Steer, K. Tilling, A. Lim, J. Marsden, T. Millar, J. Strang, Maggie Telfer, P. Vickerman, J. Macleod   +9 more
semanticscholar   +1 more source

A Study to Validate a Self-Reported Version of the ONS Drug Dependence Questionnaire [PDF]

, 2011
Aim: A prospective study to establish the reliability of a self-completion version of the Office for National Statistics (ONS) questionnaire for assessing drug dependence of substance misuse clients.
Christo G., Darke S., Gossop M., Jehanli A., Lundy A., Luty J., M. Uddin, Marsden J., McLellan A. T., Poole W. K., R. Holland, Rosen C. S., Schwartz R. H., Sherman M. F., Simpson D. D., Singleton N., V. Maskrey, Vivancos R.   +17 more
core   +1 more source

Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]

, 2009
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S., Robson , Noorzurani, Vicknasingam, B.   +2 more
core  

Ethanol reversal of tolerance to the respiratory depressant effects of morphine [PDF]

, 2015
Opioids are the most common drugs associated with unintentional drug overdose. Death results from respiratory depression. Prolonged use of opioids results in the development of tolerance but the degree of tolerance is thought to vary between different ...
A Fugelstad, A Fugelstad, Abi Lyndon, AJ Ruttenber, Anne Lingford-Hughes, AR Lingford-Hughes, B Levine, BM Mathers, CA Paronis, Chris Bailey, CK Kuo, CN Lessov, CP Bailey, CP Bailey, CP Bailey, E Kelly, E Valjent, Eamonn Kelly, EB Rex, EJ Waite, F Chen, FL Smith, FL Smith, Graeme Henderson, GS Ling, H Sakakibara, HW Matthes, HY Lin, I Rodriguez-Martin, J Llorente, J McPherson, J Reneau, JM White, Joanne Roberts, John MacLachlan, JT Williams, JW Lewis, KL McGilliard, L He, LC Hull, LC Saland, LJ Sim-Selley, LM Bohn, LQ Hong-Brown, M Aliczki, M Hickman, M Hickman, M Inoue, M Pierce, Matthew Hickman, N Quillinan, NG Shah, R Cornish, R Romberg, Rob Hill, S Darke, S Darke, S Kishioka, Sarah Withey, SJ Slater, SV Dighe, TC Green, Yvonne Kershaw   +62 more
core   +3 more sources

Analysis of Methadone-Related Poisoning Cases

Fayixue Zazhi
ObjectiveTo analyze the characteristics of methadone-related poisoning cases and provide a reference for forensic identification.MethodsA total of 71 cases of methadone-related poisoning reported from 1998 to 2023 in China and 26 cases of methadone ...
LI Ze-qi, XING Lei, ZHANG Hui-ge, HE Li-rou, ZHANG Jia-yi, WANG Jia-qi, LIU Shi-hao, YANG Wei-hong   +7 more
doaj   +1 more source