Results 11 to 20 of about 51,515 (279)

Taar1 gene variants have a causal role in methamphetamine intake and response and interact with Oprm1

open access: yeseLife, 2019
We identified a locus on mouse chromosome 10 that accounts for 60% of the genetic variance in methamphetamine intake in mice selectively bred for high versus low methamphetamine consumption. We nominated the trace amine-associated receptor 1 gene, Taar1,
Alexandra M Stafford   +9 more
doaj   +1 more source

Reciprocal Substitution Between Methamphetamine and Heroin in Terms of Reinforcement Effects in Rats

open access: yesFrontiers in Psychiatry, 2020
Heroin and methamphetamine are both popular illicit drugs in China. Previous clinical data showed that habitual users of either heroin or methamphetamine abuse the other drug for substitution in case of unavailability of their preferred drug. The present
Di-sen Mei   +9 more
doaj   +1 more source

Plasma inflammatory factors are associated with anxiety, depression, and cognitive problems in adults with and without methamphetamine dependence: An exploratory protein array study

open access: yesFrontiers in Psychiatry, 2015
Objectives: It is hypothesized that immune factors influence addictive behaviors and contribute to relapse. The primary study objectives were to: 1) compare neuropsychiatric symptoms across adults with active methamphetamine dependence, in early ...
Marilyn eHuckans   +10 more
doaj   +1 more source

Executive Control and Striatal Resting-State Network Interact with Risk Factors to Influence Treatment Outcomes in Alcohol-Use Disorder

open access: yesFrontiers in Psychiatry, 2017
Alterations within mesocorticolimbic terminal regions commonly occur with alcohol use disorder (AUD). As pathological drug-seeking behavior may arise as a consequence of alcohol-induced neuroadaptations, it is critical to understand how such changes ...
Milky Kohno   +13 more
doaj   +1 more source

Effects of Dopamine- and Serotonin-Related Compounds on Methamphetamine-Induced Self-Injurious Behavior in Mice

open access: yesJournal of Pharmacological Sciences, 2004
Methamphetamine induces hyperlocomotion, and high doses of methamphetamine induce self-injurious behavior (SIB) in rodents. It is well known that the monoaminergic system is involved in methamphetamine-induced behavior.
Tomohisa Mori   +3 more
doaj   +1 more source

Methamphetamine-induced encephalopathy in the absence of hyperammonemia

open access: yesBMC Psychiatry, 2023
Background Methamphetamine is an addictive drug with various effects on the neurotransmitters in the central nervous system. Methamphetamine-induced encephalopathy in the absence of hyperammonemia presents a unique challenge in a clinical setting ...
Jessica M Rabbany   +4 more
doaj   +1 more source

Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity. [PDF]

open access: yesPLoS ONE, 2012
Methamphetamine abuse continues to be a worldwide problem, damaging the individual user as well as society. Only minimal information exists on molecular changes in the brain that result from methamphetamine administered in patterns typical of human ...
Gurudutt Pendyala   +2 more
doaj   +1 more source

Prenatal Exposure to Methamphetamine Causes Vascular Dysfunction in Adult Male Rat Offspring

open access: yesFrontiers in Cardiovascular Medicine, 2022
Methamphetamine use during pregnancy can have negative consequences on the offspring. However, most studies investigating the impact of prenatal exposure to methamphetamine have focused on behavioral and neurological outcomes.
Hasitha Chavva   +5 more
doaj   +1 more source

Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs.

open access: yesPLoS ONE, 2020
Methamphetamine use has increased over the past decade and the first use of methamphetamine is most often when women are of reproductive age. Methamphetamine accumulates in the liver; however, little is known about the effect of methamphetamine use on ...
Jia Yin Soo   +6 more
doaj   +1 more source

Treatment utilization and barriers to treatment: Results of a survey of dependent methamphetamine users

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2011
Background Australia has one of the highest rates of methamphetamine use in the world; however, treatment access for methamphetamine is comparatively low.
Lee Nicole K   +3 more
doaj   +1 more source

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