Results 71 to 80 of about 179,944 (271)

The derivation of the formyl-group oxygen of chlorophyll b in higher plants from molecular oxygen. [PDF]

open access: yes, 1994
The mechanism of formation of the formyl group of chlorophyll b has long been obscure but, in this paper, the origin of the 7-formyl-group oxygen of chlorophyll b in higher plants was determined by greening etiolated maize leaves, excised from dark-grown
Abraham R. J.   +27 more
core   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

open access: yesAdvanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao   +6 more
wiley   +1 more source

Cynodon dactylon methanol extract potentiates stress mitigation in response to acidic stress in Labeo calbasu fingerlings

open access: yesIndian Journal of Animal Sciences, 2019
A 30-day feeding trial was conducted to study the antistress ability of dietary Cynodon dactylon methanol extract against acid stress in Labeo calbasu fingerlings.
THONGAM IBEMCHA CHANU   +6 more
doaj   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Characterization of the extracellular lipase of Bacillus subtilis and its relationship to a membrane-bound lipase found in a mutant strain [PDF]

open access: yes, 1979
Bacillus subtilis CMK33 is a mutant that is more osmotically fragile than the wild type when it is converted to the protoplast form. The protoplasts of this mutant contain a membrane-bound lipase, which is not found in protoplasts of the wild type ...
Kennedy, Mary B., Lennarz, W. J.
core  

Glycolytic reprograming in Salmonella counters NOX2-mediated dissipation of ΔpH. [PDF]

open access: yes, 2020
The microbial adaptations to the respiratory burst remain poorly understood, and establishing how the NADPH oxidase (NOX2) kills microbes has proven elusive. Here we demonstrate that NOX2 collapses the ΔpH of intracellular Salmonella Typhimurium.
Chakraborty, Sangeeta   +7 more
core  

Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells. [PDF]

open access: yes, 2017
Metformin is a widely used agent for the treatment of diabetes and infertility, however, it has been found to have anti-cancer effects in a variety of malignancies including high grade serous ovarian cancer (HGSC).
Aspuria, Paul-Joseph P   +6 more
core   +1 more source

Characteristics of Methanol Production Derived from Methane Oxidation by Inhibiting Methanol Dehydrogenase

open access: yesJournal of Korean Society of Environmental Engineers, 2011
This study was conducted to biologically convert methane into methanol. Methane contained in biogas was bio-catalytically oxidized by methane monooxygenase (MMO) of methanotrophs, while methanol conversion was observed by inhibiting methanol dehydrogenase (MDH) using MDH activity inhibitors such as phosphate, NaCl, , and EDTA.
Yeon-Sun Yoo   +8 more
openaire   +1 more source

Purification and properties of methanol dehydrogenase and aldehyde dehydrogenase from Methylobacillus glycogenes. [PDF]

open access: yesAgricultural and Biological Chemistry, 1990
Methanol dehydrogenase (MDH) and aldehyde dehydrogenase (ALDH) were purified to a homogenous state from Methylobacillus glycogenes, an obligate methylotroph. MDH (Mr 140,000) was composed of two different subunits (Mr 60,000 and 9,000) forming an α2β2 structure.
Osao Adachi   +3 more
openaire   +2 more sources

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

open access: yesAdvanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang   +16 more
wiley   +1 more source

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