Results 81 to 90 of about 107,783 (244)

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Methanol fermentation increases the production of NAD(P)H-dependent chemicals in synthetic methylotrophic Escherichia coli

Biotechnology for Biofuels, 2019
Background Methanol has attracted increased attention as a non-food alternative carbon source to sugar for biological production of chemicals and fuels.
Xin Wang, Xuelin Wang, Xiaolu Lu, Chen Ma, Kequan Chen, Pingkai Ouyang   +5 more
doaj   +1 more source

Biosensor-Based Directed Evolution of Methanol Dehydrogenase from Lysinibacillus xylanilyticus. [PDF]

Int J Mol Sci, 2021
Le TK, Ju SB, Lee HW, Lee JY, Oh SH, Kwon KK, Sung BH, Lee SG, Yeom SJ.   +8 more
europepmc   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

Advanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li, Cheng Huang, Liangqi Jiang, Zhen Li, Qing Liu, Minghua Wu   +5 more
wiley   +1 more source

Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway

Microbial Cell Factories, 2012
Βackground The methylotrophic yeast Pichia pastoris has become an important host organism for recombinant protein production and is able to use methanol as a sole carbon source.
Krainer Florian W, Dietzsch Christian, Hajek Tanja, Herwig Christoph, Spadiut Oliver, Glieder Anton   +5 more
doaj   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

Genomic Insights into Moderately Thermophilic Methanotrophs of the Genus Methylocaldum

Microorganisms
Considering the increasing interest in understanding the biotic component of methane removal from our atmosphere, it becomes essential to study the physiological characteristics and genomic potential of methanotroph isolates, especially their traits ...
Nathalie A. Delherbe, David Pearce, Sergey Y. But, J. Colin Murrell, Valentina N. Khmelenina, Marina G. Kalyuzhnaya   +5 more
doaj   +1 more source

Endogenous methanol regulates mammalian gene activity.

PLoS ONE, 2014
We recently showed that methanol emitted by wounded plants might function as a signaling molecule for plant-to-plant and plant-to-animal communications.
Tatiana V Komarova, Igor V Petrunia, Anastasia V Shindyapina, Denis N Silachev, Ekaterina V Sheshukova, Gleb I Kiryanov, Yuri L Dorokhov   +6 more
doaj   +1 more source

Preferential Binding of Lanthanides to Methanol Dehydrogenase Evaluated with Density Functional Theory. [PDF]

J Phys Chem B, 2021
Friedman R.
europepmc   +1 more source

Characteristics of Methanol Production Derived from Methane Oxidation by Inhibiting Methanol Dehydrogenase

Journal of Korean Society of Environmental Engineers, 2011
This study was conducted to biologically convert methane into methanol. Methane contained in biogas was bio-catalytically oxidized by methane monooxygenase (MMO) of methanotrophs, while methanol conversion was observed by inhibiting methanol dehydrogenase (MDH) using MDH activity inhibitors such as phosphate, NaCl, , and EDTA.
Yeon-Sun Yoo, Ji-Sun Han, Chang-Min Ahn, Dong-Hee Min, Woo-Jong Mo, Soon-Uk Yoon, Jong-Gyu Lee, Jong-Yeon Lee, Chang-Gyun Kim   +8 more
openaire   +1 more source