Injury in Aged Animals Robustly Activates Quiescent Olfactory Neural Stem Cells [PDF]
While the capacity of the olfactory epithelium (OE) to generate sensory neurons continues into middle age in mice, it is presumed that this regenerative potential is present throughout all developmental stages.
Brann, Jessica H. +4 more
core +2 more sources
Flavin-containing monooxygenases: mutations, disease and drug response [PDF]
NOTICE: this is the author’s version of a work that was accepted for publication in Trends in Pharmacological Sciences. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Phillips, IR, Shephard, EA
core +1 more source
Management and monitoring of hyperthyroid cats:a survey of Australian veterinarians [PDF]
Objectives This study sought to evaluate how Australian veterinarians approach management and monitoring of feline hyperthyroidism and compare these results with a similar survey recently performed in the UK.
Harvey, Andrea M +4 more
core +2 more sources
Effects of methimazole-induced hypothyroidism on immunohistochemical, stereomorphometric and some ultrastructural characteristics of pancreatic β-cells [PDF]
The function of pancreatic β-cells is to produce and secrete insulin, a crucial hormone in carbohydrate metabolism. The transcription factor PDX1 is required for insulin gene transcription and mature β-cell function.
Glišić Radmila +6 more
core +1 more source
Case Report A 26-year-old female with no significant medical history presented with palpitations and shortness of breath. Two weeks prior, she experienced rhinorrhea and congestion.Vital signs on admission were temperature 96.6°F, heart rate 252 beats ...
Merrill, MD, Eve
core +2 more sources
Prognostic value of thyrotropin receptor antibodies (TRAb) in Graves' disease: a 120 months prospective study [PDF]
In most trials, at least 30-60% of patients with Graves' disease treated with antithyroid drugs relapse within 2 years after therapy withdrawal. At present, there are no prognostic parameters available early in treatment to indicate patients likely to ...
AGABITI ROSEI E +8 more
core +1 more source
Stroke Mimic: A Case of Unilateral Thyrotoxic Hypokalemic Periodic Paralysis [PDF]
Thyrotoxic hypokalemic periodic paralysis (THPP) is a condition that results in transient skeletal muscle paralysis secondary to intracellular potassium sequestration.
Lajeunesse, Michael, Young, Scott
core
The clinical photograph shows bilateral leg swelling with right‐sided predominance and cutaneous changes. CT images (A–C) demonstrate abdominal and retroperitoneal lymphadenopathy, and image D shows a hypodense lytic spinal lesion, suggesting multifocal disease involving the abdomen, retroperitoneum, and spine.
Aishwarya Holi +5 more
wiley +1 more source
Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes [PDF]
The reduced drug accumulation based on enhanced drug efflux and metabolic capacity, identified in triclabendazole (TCBZ)-resistant Fasciola hepatica may contribute to the development of resistance to TCBZ.
Laura Ceballos +5 more
core +1 more source
ABSTRACT Aim Reduced placental mTOR signaling is associated with intrauterine growth restriction and impaired maternal and placental metabolism. Since maternal hypothyroidism induces intrauterine growth restriction, and maternal treatment with kisspeptin‐10 (Kp10) has been shown to improve feto‐placental development in hypothyroid rats, this study ...
Bianca Reis Santos +9 more
wiley +1 more source

