Ubiquitination in cancer: mechanisms and therapeutic opportunities
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu+7 more
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THE REPLACEABILITY OF dl-METHIONINE IN THE DIET OF THE RAT WITH ITS α-KETO ACID ANALOGUE
William M. Cahill, G Rudolph
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5‐thiohistidine N‐acetyltransferase from Proteiniphilum saccharofermentans
Ovothiol A is a 5‐thiohistidine derivative biosynthesized by a broad range of prokaryotic and eukaryotic organisms. Its redox‐active mercaptoimidazole side chain is believed to protect cells from oxidative stress. The three enzymes that produce ovothiol A from histidine, cysteine, and S‐adenosyl methionine have been identified and characterized.
Cangsong Liao+3 more
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Metabolism of Methionine and Pectin Esterification in a Plant Tissue
Clifford S. Sato+3 more
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Lysine and Methionine Supplementation of Corn-Soybean Oil Meal Rations for Pigs in Drylot [PDF]
D. C. Acker, D. V. Catron, V. W. Hays
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2‐oxoglutarate (2OG)‐dependent non‐heme iron (NHFe) enzymes constitute a family of enzymes that use 2OG and oxygen to catalyze the hydroxylation of unactivated C(sp3)–H bonds. These enzymes are of biological importance and therapeutic interest due to their role in regulating various cellular processes. Herein, we have rationally designed two classes of
Peter Windsor+3 more
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Molecular Alterations in Gastric Intestinal Metaplasia Shed Light on Alteration of Methionine Metabolism: Insight into New Diagnostic and Treatment Approaches. [PDF]
Gebrehiwot NT, Liu Y, Li J, Liu HM.
europepmc +1 more source
THE EFFECT OF CYSTEINE, HISTIDINE, AND METHIONINE ON THE PRODUCTION OF POLYCYTHEMIA BY COBALT
James M. Orten, Mary C. Bucciero
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THE REPLACEMENT OF PARA-AMINOBENZOIC ACID BY METHIONINE IN THE GROWTH OF A NEUROSPORA MUTANT [PDF]
Bernard L. Strehler
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A Tailored Phospho‐p53 Library Probes Antibody Specificity and Recognition Limitations
Site‐specifically phosphorylated isoforms of the tumor suppressor p53 – encompassing all seven known phosphorylation sites within the TAD1 domain –are created upon optimization of semisynthesis protocols. This “designer" p53 library enabled validation of phosphorylation‐specific p53 antibodies and revealed epitope masking by phosphorylation in commonly
Mateusz Hess+6 more
wiley +1 more source