Results 31 to 40 of about 4,135 (162)
Interactions of Methionine and Selenomethionine with Methionine Adenosyltransferase and Ethylene-generating Systems [PDF]
Plant Physiology, 1979 Since selenomethionine appears to be a better precursor of ethylene in senescing flower tissue of Ipomoea tricolor and in indole acetic acid-treated pea stem sections than is methionine (Konze JR, N Schilling, H Kende 1978 Plant Physiol 62: 397-401), we compared the effectiveness of selenomethionine and methionine to participate in reactions which may ...
J R, Konze, H, Kende
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Cell Reports, 2017 Summary: S-adenosylmethionine (SAM) is an important metabolite as a methyl-group donor in DNA and histone methylation, tuning regulation of gene expression. Appropriate intracellular SAM levels must be maintained, because methyltransferase reaction rates
Hiroki Shima +9 more
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Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA
Signal Transduction and Targeted Therapy, 2022 Folic acid, served as dietary supplement, is closely linked to one-carbon metabolism and methionine metabolism. Previous clinical evidence indicated that folic acid supplementation displays dual effect on cancer development, promoting or suppressing ...
Jin-Tao Li +15 more
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Methionine regulates self-renewal, pluripotency, and cell death of GIC through cholesterol—rRNA axis
BMC Cancer, 2022 Background Glioma-initiating cells (GICs) are the source of glioma cells that can self-renew, have pluripotency, and are treatment-resistant, so are the starting point for relapse and eventual death despite multimodality therapy.
Kiyotaka Yokogami +6 more
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Specific interaction of methionine adenosyltransferase with free radicals [PDF]
BioFactors, 1998 AbstractAlthough free radicals have been traditionally implicated in cell injury, and associated to pathophysiological processes, recent data implicate them in cell signaling events. Free radicals are naturally occurring oxygen‐, nitrogen‐ and sulfur‐derived species with an unpaired electron, such as superoxide, hydroxyl radical or nitric oxide.
Corrales, F.J. (Fernando José) +6 more
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Methionine adenosyltransferases in liver health and diseases
Liver Research, 2017 Methionine adenosyltransferases (MATs) are essential for cell survival because they catalyze the biosynthesis of the biological methyl donor S-adenosylmethionine (SAMe) from methionine and adenosine triphosphate (ATP). Mammalian cells express two genes, MAT1A and MAT2A, which encode two MAT catalytic subunits, α1 and α2, respectively.
Ramani, Komal, Lu, Shelly C
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S-adenosylmethionine metabolism and liver disease
Annals of Hepatology, 2013 Methionine is an essential amino acid that is metabolized mainly by the liver where it is converted to S-adenosylmethionine (SAMe) by the enzyme methionine adenosyltransferase.
José M. Mato +2 more
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Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice
Redox Biology, 2022 The metastasis-associated lung adenocarcinoma transcript1 (MALAT1) is a long noncoding RNA (lncRNA) and is known for its role in cancer development and prognosis.
Jingshu Chen +11 more
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Frontiers in Bioengineering and Biotechnology, 2018 Methylated chemicals are widely used as key intermediates for the syntheses of pharmaceuticals, fragrances, flavors, biofuels and plastics. In nature, the process of methylation is commonly undertaken by a super-family of S-adenosyl methionine-dependent ...
M. Kalim Akhtar +7 more
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The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases
PLOS ONE, 2016 Methionine adenosyltransferases MAT I and MAT III (encoded by Mat1a) catalyze S-adenosylmethionine synthesis in normal liver. Major hepatic diseases concur with reduced levels of this essential methyl donor, which are primarily due to an expression switch from Mat1a towards Mat2a.
Claudia Pérez +5 more
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