Results 61 to 70 of about 10,041 (230)

‘Acetaldehyde‐enkephalins’: elucidation of the structure of the acetaldehyde adducts of methionine‐enkephalin and leucine‐enkephalin [PDF]

FEBS Letters, 1980
The two major endogenous opioid pentapeptides, methionine-enkephalin and leucine-enkephalin [ 1,2] rapidly react with acetaldehyde, under very mild conditions, to give an ‘acetaldehyde-enkephalin’ adduct, referred to as ‘acetaldehyde-enkephalin [Met’] and ‘acetaldehyde-enkephalin [Leu”], respectively 231.
Summers, Michael C., Gidley, Michael J., Sanders, Jeremy K.   +2 more
openaire   +3 more sources

Lentil Flours as Sustainable Source of Proteins for the Food Industry

Sustainable Food Proteins, Volume 3, Issue 3, September 2025.
Lentils, due to their accessibility, sustainability, and high nutritional value, emerge as a promising option as protein flour for food development. This study evaluated different functional and nutritional properties of lentil flours. ABSTRACT The growing transition toward a plant‐based diet, coupled with the need for sustainable dietary protein ...
S. M. Pontoni, A.G. Garzón, G. D. Heinen, S.R. Drago   +3 more
wiley   +1 more source

Chronic Intermittent Ethanol and Withdrawal Suppress Evoked and Spontaneous GABA Release Onto Distinct Populations of Basolateral Amygdala Principal Neurons

Addiction Biology, Volume 30, Issue 9, September 2025.
Rat basolateral amygdala principal neurons projecting to the nucleus accumbens (BLANAc) and bed nucleus of the stria terminalis (BLABNST) represent independent cell populations. In male BLANAc neurons only (left), CIE/WD decreases feedforward GABA release from lateral paracapsular interneurons.
Michaela E. Price, Hailey X. Egido‐Betancourt, Sarah E. Sizer, Brian P. Parrish, Nancy J. Alexander, Kimberly F. Raab‐Graham, Brian A. McCool   +6 more
wiley   +1 more source

Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]

, 2004
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
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Biochemical and clinical impact of organic uremic retention solutes : a comprehensive update [PDF]

, 2018
In this narrative review, the biological/biochemical impact (toxicity) of a large array of known individual uremic retention solutes and groups of solutes is summarized.
Abel, Amann, Anneleen Pletinck, Barreto, Brownlee, Cohen, Costigan, Dhaun, Drewett, Eva Schepers, Glorieux, Griet Glorieux, Hannam-Harris, Harpel, Henderson, Hur, Kassis, Kohan, Koizumi, Kuragano, Lim, Nilsson, Niwa, Niwa, Palmer, Patel, Raymond Vanholder, Rhee, Rock, Rubin, Saxena, Sheriff, Simenhoff, Tschesche, Vadas, Vallance, Vanholder, Vanholder, Vanholder, Vannucchi, Ward, Warren, Witko-Sarsat, Yan, Zoccali, Zoccali   +45 more
core   +3 more sources

Changes in Liver Metabolome Induced by Pterostilbene and Resveratrol in a Rat Model of Liver Steatosis

Molecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Resveratrol and pterostilbene reduced the steatotic status of animals fed a high‐fat, high‐sucrose diet, involving differential and specific mechanisms of action for each stilbene. Thus, changes in riboflavin metabolism, nicotinamide mononucleotide metabolism, or in the LysoPC(18:1)‐mediated effects contribute to the specific actions of pterostilbene ...
Alfredo Fernández‐Quintela, Emily P. Laveriano‐Santos, Tania Portolés, Andreu Gual‐Grau, Juan Vicente Sancho, Maria P. Portillo   +5 more
wiley   +1 more source

Opioid receptors in cardiovascular function

British Journal of Pharmacology, Volume 182, Issue 16, Page 3710-3725, August 2025.
Opioid receptors are G protein‐coupled receptors expressed by various cells in the heart, including myocytes and nerve fibres, and play a crucial role in modulating cardiac function. These receptors influence neural transmission, heart rate and myocyte contractility, offering cardioprotection.
Venkatesh Katari, Kesha K. Dalal, Narendra Kondapalli, Sailaja Paruchuri, Charles K. Thodeti   +4 more
wiley   +1 more source

Neurotrophic factors and corneal nerve regeneration [PDF]

, 2017
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Lambiase, Alessandro, Sacchetti, Marta
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Hyperpolarization Modulation of the T‐Type hCav3.2 Channel by Human Synenkephalin [1–53], a Shrew Neurotoxin Analogue without Paralytic Effects

Angewandte Chemie, Volume 137, Issue 27, July 1, 2025.
Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka, Yusuke Yano, Nozomi Hara, Chihiro Sadamoto, Andres D. Maturana, Masaki Kita   +5 more
wiley   +1 more source

Studies on the small neuropeptide: RPCH and ENK, their function of reproductive regulation in the mud crab, Scylla paramamosain (Estampador, 1949) [PDF]

, 2013
拟穴青蟹（Scyllaparamamosain）是我国东南沿海重要的经济蟹类。本文以拟穴青蟹为研究对象，采用动物生理学、分子生物学、生物信息学等方法和手段，研究了3种小分子神经肽即红色素聚集激素（Redpigmentconcentratinghormone，RPCH）、亮氨酸-脑啡肽（Leucineenkephalin，Leu-ENK）和甲硫氨酸-脑啡肽（Methionineenkephalin，Met-ENK）的结构、特征和生殖调控功能。主要结果如下： （1 ...
曾慧
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