Results 111 to 120 of about 81,363 (150)
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Methionine sulfoxide cytochrome c
Biochemistry, 1976Cytochrome c has been chemically modified by methylene blue mediated photooxidation. It is established that the methionine residues of the protein have been specifically converted to methionine sulfoxide residues. No oxidation of any other amino acid residues or the cysteine thioether bridges of the molecule occurs during the photooxidation reaction ...
K M, Ivanetich +2 more
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Biochemical and Biophysical Research Communications, 2003
It is known that Escherichia coli methionine mutants can grow on both enantiomers of methionine sulfoxide (met(o)), i.e., met-R-(o) or met-S-(o), indicating the presence of enzymes in E. coli that can reduce each of these enantiomers to methionine (met).
Frantzy, Etienne +3 more
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It is known that Escherichia coli methionine mutants can grow on both enantiomers of methionine sulfoxide (met(o)), i.e., met-R-(o) or met-S-(o), indicating the presence of enzymes in E. coli that can reduce each of these enantiomers to methionine (met).
Frantzy, Etienne +3 more
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Archives of Biochemistry and Biophysics, 2012
There have been insufficient kinetic data that enable a direct comparison between free and peptide methionine sulfoxide reductase activities of either MsrB or MsrA. In this study, we determined the kinetic parameters of mammalian and yeast MsrBs and MsrAs for the reduction of both free methionine sulfoxide (Met-O) and peptidyl Met-O under the same ...
Geun-Hee, Kwak +2 more
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There have been insufficient kinetic data that enable a direct comparison between free and peptide methionine sulfoxide reductase activities of either MsrB or MsrA. In this study, we determined the kinetic parameters of mammalian and yeast MsrBs and MsrAs for the reduction of both free methionine sulfoxide (Met-O) and peptidyl Met-O under the same ...
Geun-Hee, Kwak +2 more
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Acetylation of methionine sulfoxide and methionine sulfone by the rat
Biochimica et Biophysica Acta (BBA) - General Subjects, 1972Abstract About 12% of the radioactivity of [Me-14C]methionine sulfoxide injected into rats was excreted in the urine in 24 h. N-Aceytlmethionine sulfoxide contained about 65% of the radioactivity excreted. The N-acetylcholamine sulfoxide was identified by its co-chromatography on paper with the chemically synthesized compound and its deacetylation to
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Analytical Biochemistry, 1982
Abstract A simple and rapid assay has been developed to measure the enzymatic activity of peptide methionine sulfoxide reductase. The assay is based on the reduction of labeled N-acetylmethionine sulfoxide to N-acetylmethionine. The N-acetylmethionine can be separated from the substrate by extraction into ethyl acetate.
N, Brot +3 more
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Abstract A simple and rapid assay has been developed to measure the enzymatic activity of peptide methionine sulfoxide reductase. The assay is based on the reduction of labeled N-acetylmethionine sulfoxide to N-acetylmethionine. The N-acetylmethionine can be separated from the substrate by extraction into ethyl acetate.
N, Brot +3 more
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ENZYME IMMUNOASSAY FOR METHIONINE‐ENKEPHALIN SULFOXIDE
Clinical and Experimental Pharmacology and Physiology, 1990SUMMARY1. An immunoassay technique employing an enzyme‐labelled ligand was developed for the sulfoxide derivative of the opioid peptide methionine‐enkephalin (MOE).2. The sensitivity of the enzyme immunoassay (EIA) was approximately twofold higher than that achieved in the radio‐immunoassay (RIA) using tritiated ligand.
G K, Tiong, J E, Olley
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The enzymology and biochemistry of methionine sulfoxide reductases
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2005The methionine sulfoxide reductase (Msr) family is composed of two structurally unrelated classes of monomeric enzymes named MsrA and MsrB, which display opposite stereo-selectivities towards the sulfoxide function. MsrAs and MsrBs, characterized so far, share the same chemical mechanism implying sulfenic acid chemistry.
Boschi-Muller, Sandrine +3 more
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Transport and utilization of methionine sulfoxide in the rabbit
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1982Methionine sulfoxide is transported into purified intestinal and renal brush border membrane vesicles from rabbit by an Na+-dependent mechanism and is accumulated inside the vesicles against the concentration gradient. Both in intestine and kidney, the rate of transport is enhanced with increasing concentrations of Na+ in the external medium ...
V, Ganapathy, F H, Leibach
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Reduction of methionine sulfoxides by Escherichia coli
Archives of Biochemistry and Biophysics, 1953Abstract The reduction of the sulfoxides of methionine by Escherichia coli occurs in the presence of molecular hydrogen. By comparing the rates of reduction of some of the isomers of methionine sulfoxide it has been observed that the configuration of the asymmetric sulfur atom markedly influences this rate, whereas that of the α-carbon atom is of ...
T L, SOURKES, Y, TRANO
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Drosophila Methionine sulfoxide reductase A is not a methionine oxidase
Free Radical Biology and Medicine, 2017Methionine sulfoxide reductase A (MsrA) stereospecifically catalyzes the reduction of S-methionine sulfoxide to methionine and is important in defense against oxidative stress. Recently, we reported that mammalian methionine sulfoxide reductase A stereospecifically and selectively oxidizes Met77 in calcium-bound calmodulin and can fully reduce it as ...
Sreya Tarafdar +3 more
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