Results 61 to 70 of about 180,383 (183)

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

Energetic dysregulations in psychotic disorders: Targets for new therapeutics

The FEBS Journal, EarlyView.
The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson, Kai‐Christian Sonntag, Thao Do Vy Le, Kaitlin Shannon, Chao Wang, Fei Du, Xi Chen, Donna McPhie, Dost Ongur, Bruce Cohen, Virginie‐Anne Chouinard   +10 more
wiley   +1 more source

Repair of oxidized proteins: Identification of a new methionine sulfoxide reductase

, 2001
cited By 229International audienceOxidation of methionine residues to methionine sulfoxide can lead to inactivation of proteins. Methionine sulfoxide reductase (MsrA) has been known for a long time, and its repairing function well characterized.
Mitchell, J.K., Barras, F., Briand, C., Ezraty, Benjamin, Lafitte, D., Derrick, P.J., Grimaud, R.   +6 more
core   +2 more sources

Evolutionary Conserved and Divergent Responses to Copper Zinc Superoxide Dismutase Inhibition in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn, Fabian B. Haas, Benjamin G. Chavez, Bernd H. Dreyer, Erik V. Reiss, Anne Ziplys, Heiko Weichert, Saskia Hiltemann, José M. Ugalde, Andreas J. Meyer, John C. D'Auria, Stefan A. Rensing, Jos H. M. Schippers   +12 more
wiley   +1 more source

Methionine Sulfoxide Reduction and Assimilation in Escherichia coli: New Role for the Biotin Sulfoxide Reductase BisC

, 2004
International audienceABSTRACT Methionine ranks among the amino acids most sensitive to oxidation, which converts it to a racemic mixture of methionine- S -sulfoxide (Met-S-SO) and methionine- R -sulfoxide (Met-R-SO).
B. Ezraty, J. Bos, Bos, Julia, Ezraty, Benjamin, F. Barras, L. Aussel, Aussel, Laurent, Barras, Frédéric   +7 more
core   +1 more source

Leishmania major methionine sulfoxide reductase A is required for resistance to oxidative stress and efficient replication in macrophages. [PDF]

PLoS ONE, 2013
Leishmania are protozoan parasites that proliferate within the phagolysome of mammalian macrophages. While a number of anti-oxidant systems in these parasites have been shown to protect against endogenous as well as host-generated reactive oxygen species,
Fiona M Sansom, Leonie Tang, Julie E Ralton, Eleanor C Saunders, Thomas Naderer, Malcolm J McConville   +5 more
doaj   +1 more source

Multiplexed Nanosensors for Real‐Time Monitoring of VOC‐Mediated Signalling Response in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT To enhance crop performance, intercropping strategies leverage volatile organic compound (VOC)‐driven interactions with companion plants that constitutively emit VOCs. Despite the agricultural importance, the mechanisms and kinetics of VOC‐mediated sensory transduction in receiver plants eavesdropping on neighbouring non‐kin emitters remain ...
Mervin Chun‐Yi Ang, Jolly Madathiparambil Saju, Sayyid Mohaideen, Niha Dhar, Sarangapani Sreelatha, Sayuj Koyyappurath, Thomas K. Porter, Gabriel Sánchez‐Velázquez, Vaishnavi Reddy Amarr, Song Wang, Duc Thinh Khong, Suh In Loh, Michael S. Strano, Sarojam Rajani   +13 more
wiley   +1 more source

Methionine sulfoxide reductase regulates brain catechol-O-methyl transferase activity [PDF]

, 2014
This is the published version. Copyright 2014 Oxford University PressCatechol-O-methyl transferase (COMT) plays a key role in the degradation of brain dopamine (DA).
Moskovitz, Jackob, Cruz, Dianne A., Bortolato, Marco, Walss-Bass, Consuelo, Thompson, Peter M.   +4 more
core   +1 more source

The Methionine Sulfoxide Reduction System: Selenium Utilization and Methionine Sulfoxide Reductase Enzymes and Their Functions [PDF]

Antioxidants & Redox Signaling, 2013
Selenium is utilized in the methionine sulfoxide reduction system that occurs in most organisms. Methionine sulfoxide reductases (Msrs), MsrA and MsrB, are the enzymes responsible for this system. Msrs repair oxidatively damaged proteins, protect against oxidative stress, and regulate protein function, and have also been implicated in the aging process.
openaire   +2 more sources

Substrate Binding in Free Methionine-R-sulfoxide Reductase [PDF]

Journal of Biological Chemistry, 2010
Recently, the group of Chi and co-workers published the crystal structures of the reduced, substrate-bound, and oxidized forms of fRMsr from Staphylococcus aureus (1). In parallel, our group proposed a catalytic mechanism of free methionine-R-sulfoxide (Met-R-O) reductase (fRMsr) from Neisseria meningitidis based on crystal structure and biochemical ...
Gruez, Arnaud, Libiad, Marouane, Boschi-Muller, Sandrine, Branlant, Guy   +3 more
openaire   +2 more sources