Results 71 to 80 of about 180,383 (183)

Identification of a truncated form of methionine sulfoxide reductase a expressed in mouse embryonic stem cells

Journal of Biomedical Science, 2011
Background Methionine Sulfoxide Reductase A (MsrA), an enzyme in the Msr gene family, is important in the cellular anti-oxidative stress defense mechanism.
Lemanski Sharon L, Kochegarov Andrei A, Huang Xupei, Jia Yuanyuan, Webster Keith A, Zhang Chi, Jia Pingping, Lemanski Larry F   +7 more
doaj   +1 more source

Excessive training does not induce mitochondrial dysfunction or impair insulin signalling within skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of overtraining in trained endurance athletes reduced exercise performance without impairing glucose tolerance. In skeletal muscle, overtraining was associated with increased expression of lipid metabolism‐related proteins, enhanced mitochondrial biogenesis and preserved insulin signalling, despite elevated oxidative ...
Geneviève J. DesOrmeaux, Henver S. Brunetta, Pierre‐Andre Barbeau, Alexandra M. Coates, Christopher Pignanelli, Fasih A. Rahman, Jamie F. Burr, Graham P. Holloway   +7 more
wiley   +1 more source

Hepatic overexpression of methionine sulfoxide reductase A reduces atherosclerosis in apolipoprotein E-deficient mice

Journal of Lipid Research, 2015
Methionine sulfoxide reductase A (MsrA), a specific enzyme that converts methionine-S-sulfoxide to methionine, plays an important role in the regulation of protein function and the maintenance of redox homeostasis.
Yan-Yong Xu, Fen Du, Bing Meng, Guang-Hui Xie, Jia Cao, Daping Fan, Hong Yu   +6 more
doaj   +1 more source

Drought and salinity stress remodel Asian rice (Oryza sativa) leaf development through cell‐type‐specific regulatory programs

New Phytologist, Volume 252, Issue 4, Page 1376-1395, November 2026.
Osmotic stressors induce developmental and physiological changes in rice (Oryza sativa) seedlings, which are modulated by cell‐type‐specific gene expression and regulatory networks. We exposed plants to two levels of drought and salinity stress and measured the effects of these stressors on developing leaves by measuring physiological traits, ion ...
Sean M. Robertson, Obaid Maqsood, Chi Dang, Asher Pasha, Claudio Stasolla, Nicholas J. Provart, Olivia Wilkins   +6 more
wiley   +1 more source

Thioredoxins and Methionine Sulfoxide Reductases in the Pathophysiology of Pneumococcal Meningitis [PDF]

Journal of Infectious Diseases, 2016
Pneumococcal proteins involved in the resistance against oxidative stress are present in all strains and therefore are potential antigens that could be suitable for new therapies and/or vaccines. Their role in the pathogenesis of pneumococcal meningitis has not been addressed.We investigated the individual contributions of extracellular thioredoxin ...
Ribes, Sandra, Abdullah, Mohammed R., Saleh, Malek, Hanisch, Uwe-Karsten, Nau, Roland, Hammerschmidt, Sven   +5 more
openaire   +3 more sources

One Hundred Years of Sulfido Ligand in the Molybdenum Cofactor: New Perspectives

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
The terminal sulfido ligand in mononuclear molybdoenzymes has been appreciated for almost 125 years, with the characterization of Schardinger's enzyme in cow's milk, now known to be xanthine oxidase, that was isolated in 1902 in Vienna, Austria. The ligand is found in molybdoenzymes identified across all kingdoms of life.
Silke Leimkühler, Benjamin R. Duffus, Carola Schulzke   +2 more
wiley   +1 more source

The Role and Regulatory Mechanism of Methionine Sulfoxide Reductase (Msr) in the Process of Chilling Injury of Fruits and Vegetables: A Review

Horticulturae
The failure to promptly eliminate excessive reactive oxygen species (ROS) leads to the oxidation of biological macromolecules such as proteins, which is a key factor in chilling injury (CI) in harvested fruits and vegetables.
Feilong Yin, Liang Shuai, Mohd Termizi Yusof, Nurul Shazini Ramli, Azizah Misran, Yunfen Liu, Meiying He, Yuanli Liang, Mohd Sabri Pak Dek   +8 more
doaj   +1 more source

Genomics and X-ray microanalysis indicate that Ca2+ and thiols mediate the aggregation and adhesion of Xylella fastidiosa

Brazilian Journal of Medical and Biological Research, 2002
The availability of the genome sequence of the bacterial plant pathogen Xylella fastidiosa, the causal agent of citrus variegated chlorosis, is accelerating important investigations concerning its pathogenicity.
B. Leite, M.L. Ishida, E. Alves, H. Carrer, S.F. Pascholati, E.W. Kitajima   +5 more
doaj   +1 more source

Sacrificial Methionine Residues Protect Active‐Site Histidines From Oxidation

Angewandte Chemie Novit, Volume 2, Issue 3, September 2026.
Methionine residues near the active site of human ribonuclease 1 act as sacrificial antioxidants, protecting catalytic histidines from oxidation by reactive oxygen species (ROS). Chemoselective capping with an oxaziridine and total chemical synthesis with a sulfur‐free norleucine isostere each render the enzyme more susceptible to oxidative ...
Evans C. Wralstad, Jessica Sayers, Giulio Fittolani, David Sarabia‐Castillo, Alex J. Callahan, Bradley L. Pentelute, Ronald T. Raines   +6 more
wiley   +1 more source

Characterization and solution structure of mouse myristoylated methionine sulfoxide reductase A

, 2012
Methionine sulfoxide reductase A is an essential enzyme in the antioxidant system which scavenges reactive oxygen species through cyclic oxidation and reduction of methionine and methionine sulfoxide.
Ghesquière, Bart, Gruschus, James M, Piszczek, Gregorz, Kim, Geumsoo, Levine, Rodney L, Piszczek, Grzegorz, Tjandra, Nico, Gruschus, James M., Lim, Jung Chae, Levine, Rodney L.   +9 more
core   +1 more source