Results 91 to 100 of about 1,892,546 (315)
An Examination of a New Psychometric Method for Optimizing Multi-Faceted Assessment Instruments in the Context of Trait Emotional Intelligence. [PDF]
, 2015 Driven by the challenge of representing and measuring psychological attributes, this article outlines a psychometric method aimed at identifying problem facets.
Petrides, KV +2 more
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Analytical Method Validation Characteristics. [PDF]
, 2017 Analytical Method Validation Characteristics.
Pelagia Anastasiadou (3684904) +3 more
core +1 more source
Urinary 8-oxo-7,8-dihydroguanosine as a Potential Biomarker of Aging
Frontiers in Aging Neuroscience, 2018 Background: A molecular biomarker of physiologic age, as opposed to chronologic age, is needed in clinical medicine. 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGsn) and 8-oxo-7, 8-dihydroguanosine (8-oxoGsn) are two promising aging biomarkers.Methods: A ...
Wei Gan +9 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Química Nova, 2015 17α-methyltestosterone (17α-MT) is a hormone used in medicine and aquaculture which can be found in natural waters. It is considered an emerging organic pollutant and its accurate and precise analysis is required.
Luciane Miranda +5 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The importance of validation methods to facilitate the work of commodity laboratories [PDF]
, 2022 Globalization has increased the trade flow of regional products between countries, making nec-essary controls to guarantee the safety and authenticity of exported and imported food products.
dini irene
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A computer intensive method for choosing the ridge parameter [PDF]
In this paper we describe a computer intensive method to find the ridge parameter in a prediction oriented linear model. With the help of a factorial experimental design the method is tested and compared to a classical one.
Weihs, Claus +2 more
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