Results 81 to 90 of about 1,892,546 (315)
Estimating the Number of Clusters Using Cross-Validation [PDF]
, 2019 Many clustering methods, including k-means, require the user to specify the number of clusters as an input parameter. A variety of methods have been devised to choose the number of clusters automatically, but they often rely on strong modeling ...
Patrick O. Perry (7036736) +1 more
core +1 more source
Scientia Pharmaceutica, 2019 An isocratic high-performance liquid chromatographic method using electrochemical detection (HPLC-ECD) for the quantitation of clarithromycin (CLA) was developed using Response Surface Methodology (RSM) based on a Central Composite Design (CCD).
Pedzisai A. Makoni +3 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Numerical validation of the delaunay normalization and the Krylov-Bogoliubov-Mitropolsky method [PDF]
, 2014 A scalable second-order analytical orbit propagator programme based on modern and classical perturbation methods is being developed. As a first step in the validation and verification of part of our orbit propagator programme, we only consider the ...
Pérez, I. [0000-0003-2916-1150] +3 more
core +1 more source
Multicenter Analytical Validation of Aβ40 Immunoassays
Frontiers in Neurology, 2017 BackgroundBefore implementation in clinical practice, biomarker assays need to be thoroughly analytically validated. There is currently a strong interest in implementation of the ratio of amyloid-β peptide 1-42 and 1-40 (Aβ42/Aβ40) in clinical routine ...
Linda J. C. van Waalwijk van Doorn +17 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Evaluation and Application of Best Practice in Analytical Method Validation [PDF]
The coherent body of research described in the existing published work is concerned with new assay method development and validation using novel systematic approaches for pharmaceutical and diagnostic compounds.
Shabir, Ghulam
core
UV derivative spectrophotometric method for determination of estradiol valerate in tablets
Química Nova, 2010 A derivative UV spectrophotometric method for determination of estradiol valerate in tablets was validated. The parameters specificity, linearity, precision, accuracy, limit of detection and limit of quantitation were studied according to validation ...
Andreas S. L. Mendez +2 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
clValid: An R Package for Cluster Validation [PDF]
The R package clValid contains functions for validating the results of a clustering analysis. There are three main types of cluster validation measures available, "internal", "stability", and "biological".
Susmita Datta +3 more
core +1 more source